Nine experts from the national pharmaceutical industry and relevant personnel from Red Star Pharmaceutical Factory gathered at the hot spring resort, where Fang Hanmin's "new hydrogenation reduction process" will be reviewed by several top domestic experts.
The appraisal meeting was chaired by Chief Hou of the Human Resources Department. According to the agenda, Fang Hanmin first introduced the background and concept of this technology, as well as what problems the process solved and what results were achieved.
In fact, these contents were elaborated in the appraisal materials, but there was a procedure in the appraisal, and Fang Hanmin had to repeat it as required.
The second procedure of the appraisal meeting is to ask questions from experts. When introducing the review members, the host specially introduced the review team leader Professor Fei, who is the vice president of the nationally renowned Shin Kong Pharmaceutical Industry Research Institute and the founder of domestic modern pharmaceutical research. Famous expert in the pharmaceutical industry, professor-level senior engineer, master's and doctoral tutor.
Before asking questions, Professor Fei made an opening statement: "I am deeply honored to be invited to participate in the technical appraisal meeting of the 'New Hydrogenation Reduction Process' of the Red Star Pharmaceutical Factory! I received the appraisal materials from the Red Star Pharmaceutical Factory and spent a few days I studied the contents in detail, and to be honest, I was very shocked by the contents of the project. I did not expect that such cutting-edge process technology could be the first to achieve breakthroughs in a local state-owned pharmaceutical factory and achieve industrial production."
Professor Fei paused and continued: "As far as I know, hydrogenation reduction technology, even in Western developed countries, has only just been initially applied in the field of petrochemical industry. In pharmaceutical engineering, this technology is still in the exploratory and experimental stage. There is still a long way to go before practical application. Chief Fang, what I want to know is, do you have a technical reference before developing the catalytic hydrogenation process?"
Although the experts on the review team do not yet know Fang Hanmin's academic background and technical titles, and their questions are completely centered around the content of the technical appraisal, Fang Hanmin must be cautious in his answers, otherwise his identity will be easily exposed.
The so-called technical reference refers to the reference to ready-made technical data. Fang Hanmin is a doctor of pharmaceutical science from Oxford University who traveled back to the 21st century. This technology is basically copied from the mature process of the 21st century, but this is his secret. , never let outsiders know.
After thinking for a moment, Fang Hanmin said calmly: "As Professor Fei said, hydrogenation reduction technology has been used in the petrochemical industry in developed countries, and in many large pharmaceutical companies in the pharmaceutical industry, such as Johnson & Johnson, DuPont, and Bayer. , Amoco, AstraZeneca-Gyrica, RGP and Takeda Pharmaceuticals, etc., have also conducted a large number of exploratory experiments and achieved some results. Our technical reference is the public publication of these large companies in various journals and magazines. research paper."
Professor Fei nodded, "It should be said that your sense of smell for capturing or tracking foreign cutting-edge technologies is sensitive enough. This makes me, a professional engaged in medical research, ashamed, because we have also seen it from foreign materials. Reporting in this regard, but our exploration in the laboratory has not yet started. You have all achieved industrialization! Chief Fang, I believe you also know that the hydrogenation process has high requirements for both equipment and operators. Considering this , many people would rather take a detour than deal with the hydrogenation process. Did you have no concerns when you developed this technology?"
In the 21st century that Fang Hanmin has experienced, the concept of environmental protection has taken root in people's minds. After graduating with his doctorate, he worked as a project manager at the New Drug Creation Center of the European RGP Company. There, no matter the working environment or people's ideas, green has long been Development comes first.
The famous Professor Fei raised a question that ordinary people are concerned about. Because this is a technical achievements appraisal meeting, Fang Hanmin has the obligation to answer no matter what the review experts ask.
After thinking about it for a while, Fang Hanmin said: "Most people don't want to deal with the hydrogenation process, mainly because they are afraid of the dangers of hydrogen. Yes, if the properties of hydrogen are not understood clearly and strict rules for use and protection are formulated, this kind of The gas is indeed dangerous, and it is very troublesome to formulate usage and protection rules based on previous experience and the properties of hydrogen. However, compared with the problems that the hydrogenation process has to solve, this is nothing!"
"In the second workshop of Hongxing Pharmaceutical Factory, the original old process has major technical problems such as serious pollution, high scrap rate, and unstable product quality. We are going to use the new hydrogenation reduction process to fundamentally solve the problems of the old process. Facts It proves that the new process not only completely eliminates environmental pollution, but also greatly improves product quality and yield. Such a result is exactly what the company wants!"
"I'll ask another question, which is also my last question, and then leave the opportunity to ask questions to other review experts. Section Chief Fang, everyone knows that hydrogen is a flammable and explosive gas. How do you provide safety education to employees? ?How to avoid safety accidents in the actual production process?"
“Since we decided to use hydrogenation reduction technology to replace the original old process, we have strengthened further safety education for our employees. All personnel related to the production line must undergo strict safety assessments before taking up their posts, and they can only take up their posts after passing the test. Strengthening safety education has resulted in The results have been very good, and there have never been any safety incidents since the new hydrogenation reduction process was put into production.”
Another review expert may be a little impatient to wait. As soon as Fang Hanmin finished speaking, he raised his hand and asked: "Chief Fang, I read your appraisal materials carefully. Compared with the original old process, the various economic and technical aspects of the new process are The indicators are perfect, and I am deeply impressed by this project. What I want to ask is, more than half a year after it was put into production, is there any difference in the service life of the palladium-carbon catalyst in actual production compared with the experimental stage? How big of a difference is it? Because palladium It is a precious metal, and the impact of catalyst ordering on product cost cannot be ignored.”
"Thank you Professor Wang for your question!" After being polite, Fang Hanmin said: "Professor Wang attaches great importance to the economics of process technology. This is worth learning, because the purpose of building a product-based enterprise without violating laws and regulations is to Create economic benefits. However, more than eight months since the new process was put into operation, the first batch of palladium-carbon catalysts loaded into the equipment have not shown signs of reduced activity and are still in normal use. The catalyst life in the experimental stage is only more than seven moon."
Professor Wang was quite surprised, "Oh, can you explain the reason for this situation?"
"I believe that the reason why the catalyst life is extended in the actual production process is mainly because the process conditions are controlled more accurately. In the experimental stage, the process was completely manual. In actual production, most of our positions adopt automatic control. After the human factors are reduced, the process indicators are more optimized and the impact on the catalyst is reduced, which is naturally conducive to extending the service life."
"Well----, your explanation is reasonable and reasonable, I am very convinced! Okay, I have no problem." Professor Wang looked satisfied.
"Chief Fang, I have a question to ask you." Another review expert asked to ask a question.
"Professor Liu, please don't say that. In front of you, I am just a primary school student, and I have to ask you for more advice." Fang Hanmin made a gesture of invitation.
"I want to know how you plan to dispose of the palladium-carbon catalyst after it reaches the end of its service life? As Professor Wang said, palladium is a precious metal. If it is not handled properly, it will affect the cost of your products."
"Thank you Professor Liu for the reminder! Yes, even if the palladium carbon catalyst has reached its service life, its value should not be ignored, and it is still a kind of solid waste. Whether from an economic point of view or to protect the environment, we must Recycling of spent catalysts not only recovers the precious metals, but also harmlessly disposes of solid waste."
"What a great idea! Is this the so-called green environmental protection concept? Chief Fang, let me ask another off-topic question. Do you have any technology for the harmless treatment of waste catalysts?"
This topic indeed has nothing to do with the results appraisal, and Fang Hanmin did not write it into the appraisal materials at the time, but when the review expert raised it, he could not avoid it, "Although we have designed a technical solution for the harmless treatment of spent catalysts, because there are still There is no waste catalyst for testing, and frankly speaking, we have not carried out harmless treatment tests yet, but I believe this link will not be missing."
"I agree with your point of view. No matter what aspect you consider, the spent catalyst should be fully recycled. If this step is done well, your new hydrogenation reduction process will be perfect!"
"Professor Liu, please rest assured that once the conditions are met, we will immediately carry out relevant experiments and will never disappoint the experts' expectations."
"Chief Fang, I have carefully read the appraisal materials of the project. You have made remarkable achievements. I am gratifying to congratulate you! But I also found a problem, that is, whether it is a small test or a pilot test, the appraisal materials provide The test information is very limited. I wonder what the consideration is? Is this a measure you have taken to keep technical secrets?"
If it were not for the fear of exposing his identity as a time traveler, Fang Hanmin would not have to hide anything when faced with such a problem. However, the new hydrogenation and reduction process is after all a technology he brought from his previous life. The small and medium trials were just for show, to deceive others. Because more than 90% of the test process was streamlined, the test data obtained was of course very little, and Fang Hanmin could only use other excuses.
"The issues mentioned by Professor Huang make me feel ashamed. Indeed, in order to reduce the length of identification materials, we only selected a few representative sets of experimental data, failing to allow experts to see enough experimental data to illustrate our We did not pay enough attention to this issue and did not do the preparation work carefully, which should be taken as a warning. As for the technical confidentiality considerations, I think it is not that serious. The main reason is that our preparation work is not good enough."
Although this question was raised, Professor Huang did not seem to care much about the reason. "I am just discussing the matter based on the requirements for identification of materials. I believe you have very detailed test data. Otherwise, such good results will not be achieved. Although it is reflected in There is not much data in the identification materials, but it does not affect the technological advancement of the new hydrogenation reduction process at all. This technology has been successfully used in industrial production, which is enough to explain everything."
"Thank you Professor Huang for your trust!"
Professor Xu from another nationally renowned medical research institution, whose reputation is well-known in the industry, has long wanted to speak. Perhaps the previous experts were too enthusiastic, but Professor Xu behaved more like a gentleman. He waited until others had asked questions before he raised his hand. Signal.
The host understood it and said, "Professor Xu, do you have any questions? Please ask."
"Red Star Pharmaceutical Factory is the first in the country to apply hydrogenation reduction technology to the pharmaceutical industry. Chief Fang, you are a pioneer in the country in this regard. Do you think there are any shortcomings in this technology?"
