Except for a few test workers from the second workshop, others may not know that Fang Hanmin is a workaholic. He doesn't like to sit around and talk and talk. No matter what he asks others to do, he must do it first.
After receiving the notice to work in the Technical Department, several young college students were very happy. When they finally learned that working in the Technical Department was not to sit in an office, but to do experiments in the laboratory, they were a little disappointed. When they learned about the organization's The leader was just a young man with neither education nor qualifications. They seemed even more disappointed, but at this point, it was impossible to ask for a return to their original job, so they had no choice but to stay.
At the first meeting of the scientific research team, several college students saw Fang Hanmin's true face in Lushan. Although he was very young, his words and deeds appeared to be very mature, especially Fang Hanmin's ideas and the quality he showed when introducing scientific research projects. His knowledge and knowledge made several young people feel that they were even better than their teachers in college.
Of course, in the eyes of several college students, Fang Hanmin might be suspected of being an armchair strategist, but at least what he said was clear-cut and made a good first impression on them. As for whether this young deputy section chief had real skills, they could only wait and see. .
The factory's laboratory for the scientific research team is located in the northeast corner of the Red Star Pharmaceutical Factory. There is a square meter here. It was initially planned to be the central laboratory of the entire factory. Later, because each workshop had its own independent laboratory, the central laboratory could not be organized. Since then, these ten bungalows have been put to no use. They were used as warehouses for a few years. The custodian of the Supply and Marketing Department thought it was too far from the office and no one wanted to go there, so he moved the warehouse away. These houses were Completely idle.
Fang Hanmin requested the factory to repair this row of houses and beautify the surrounding environment. At the same time, he proposed a purchase list of scientific research equipment and raw materials to the supply department. These requests were unconditionally supported by Director Yuan.
Half a month later, not only had the house been repaired, the surrounding environment had been beautified, and the road leading here had been widened, but the water and electricity in the laboratory had been connected, and scientific research equipment and raw materials had also arrived one after another. Fang Hanmin divided his staff into two groups. One group was headed by Jiang Guoxin, who was at level 77, and Wan Cheng, who was at level 79. The second group was headed by Xu Hui, who was at level 78, and Guo Peng, who was at level 79.
In the hydrogenation reduction process, the primary issue is catalyst preparation. If the catalyst preparation problem is solved, at least half of the technical problems of this process will be solved.
According to Fang Hanmin’s understanding of this process technology in his previous life, para-nitrophenol is used as raw material and acetaminophen is produced by hydrogenation and reduction. The best catalyst is Pd/C (palladium carbon catalyst). The performance of this catalyst The preparation process and performance evaluation process were already quite mature and standardized in Fang Hanmin's previous life. He only had to repeat the test process in the laboratory to let the scientific research team see the magic of future technology, and to give an explanation to Factory Director Yuan and Mr. Xia.
According to the professional characteristics of the four college students, Fang Hanmin asked one group to be responsible for the preparation of the catalyst. The instruments and equipment used naturally had to be installed and debugged by themselves. The second group was responsible for the performance evaluation of the catalyst, because this work could only be carried out after the catalyst preparation was completed. Therefore, the ordered equipment will arrive later.
The employees of the second group had no experiments to do for the time being. Fang Hanmin handed the pre-drawn catalyst performance evaluation process flow chart to Xu Hui and Guo Peng, the leaders of the second group, and asked them to have a perceptual understanding of the experiment based on the operating procedures.
Xu Hui is a college student in grade 7 or 8. He took the college entrance examination as a past student. He is six or seven years older than Fang Hanmin. Although he is not convinced by Fang Hanmin in his heart, on the surface he still has the older look. With the appearance of a big brother, Fang Hanmin can complete the tasks ordered by Fang Hanmin to the letter.
Guo Peng, who was in the same group, took the college entrance examination as a fresh high school student in 1979. At that time, there was no such thing as a top student, but this guy was a well-known top student in the school in high school. Otherwise, in an era when the enrollment rate was extremely low, he would It is impossible to get into a prestigious domestic school. Because he and Fang Hanmin were of the same age, he always wanted to find opportunities to test Fang Hanmin to test whether the young deputy section chief had real talent or knowledge.
One morning, Fang Hanmin passed by the second group. They were discussing the upcoming experiment. Guo Peng suddenly shouted, "Chief Fang, please stay!"
Fang Hanmin turned around and came back, "Guo Peng, what do you want?"
"I have a few questions that I need to ask you."
"We can't talk about asking for advice. Let's discuss it with each other. What's the problem? Please talk."
"The liquid phase reduction method uses hydrogen as the reducing agent. Everyone knows that the solubility of hydrogen in any solvent is very low. It has no chance of contact with the raw materials. How do you think they react? Just like when I find a girlfriend, I How can you find a girlfriend if you don't have the opportunity to meet and interact with them?" Guo Peng's words were very funny and made everyone present laugh, but the truth is really the same.
Fang Hanmin also smiled and said, "Yes, without contact, nothing will happen. However, there is a term called 'specific surface area'. I believe you must know its meaning better than me."
"Comparing surfaces? I learned it in college, so of course I know what it means."
"Let me just say, college students have a wide range of knowledge, and such small problems are not a problem for you. Back to your question just now, the palladium carbon catalyst we use has a very high specific surface area, and the metal attached to the catalyst skeleton Palladium has special adsorption capacity for hydrogen. A large amount of hydrogen adsorbed on the specific surface of the catalyst greatly increases the contact opportunities and contact time with the material. The reduction and selectivity of hydrogen to carbon-oxygen double bonds are very ideal. This is The basic principles of the hydrogenation reduction process in the presence of palladium carbon catalyst." Fang Hanmin spoke calmly.
Originally thinking that Fang Hanmin had never gone to college, Xu Hui and Guo Peng both wanted to see him embarrassed when he could not answer the questions. Unexpectedly, this peer with neither academic qualifications nor qualifications not only answered the questions satisfactorily, but also had clear concepts and logic. Clear.
Before the mid-1980s, palladium-on-carbon catalysts had just been used in industrial production abroad, and domestic research in this area had not yet started. When Xu Hui and Guo Peng were in college, although the relevant majors had courses on solid catalysts, they did not involve palladium. Preparation and application of carbon catalysts. Fang Hanmin's answer will explain the working principle of palladium carbon catalyst, which will give two college students in the new era a refreshing feeling.
However, Guo Peng, a young man who thought he was smart, did not intend to give up. He wanted to continue testing Fang Hanmin, "Chief Fang, if you have time, I would like to discuss a few more issues with you."
"That's right, let's discuss it. Let's discuss it with each other. However, it would be better if you correct the way you address me."
"Is there a problem with your title? If I don't call you Section Chief Fang, how should I call you?"
"Guo Peng, we are basically the same age. Some of us are only a few years older at most. It's a bit vulgar to call us brothers, and it's not allowed in our workplace. I think it's best to call people of the same age by their first names."
"But you are the deputy section chief after all, and my title does not elevate you. What's inappropriate?"
"It's better to call him by his first name, don't call him by title, it will appear cordial."
"Okay. My question is that hydrogenation reduction is a gas-liquid reaction. The conditions you gave are to operate under normal pressure, but textbooks and general technical information say that gas-liquid reactions are best performed under pressure. It is carried out under conditions, and the higher the pressure above the liquid, the more gas solutes will be dissolved into the liquid, which is more beneficial to the reaction. Why can't our hydrogenation reaction be carried out under pressure?" Guo Peng may have his own purpose, But he obviously used his brains to ask such a question. This kind of question has a certain technical content.
Fang Hanmin usually doesn’t talk much, but he likes to discuss technical issues with others, “Yes, according to Henry’s law, the higher the gas pressure above the solution, the greater the solubility of the gas in the solution, but this law is not applicable to liquid phase hydrogenation. It is basically not applicable in reactions. There are two reasons. First, hydrogen is different from other gases. The increase or decrease in pressure has little effect on its solubility in the solution, but the requirements for equipment are doubled because of the penetration of hydrogen. It is extremely toxic and prone to explosion hazards. It is difficult for general equipment and sealing measures to meet its requirements. The benefits of increasing pressure are not worth the loss."
"Second, the success of the hydrogenation reduction method depends on the adsorption effect of the palladium-carbon catalyst on hydrogen, not on the solubility of hydrogen in the solution. Increasing the pressure of hydrogen has almost nothing to do with the adsorption effect of the catalyst. To sum up, As stated, it is not necessary for this process to operate under pressure.”
Although Fang Hanmin was secretly surprised by Fang Hanmin's answer, Guo Peng remained silent, "I also checked some technical information. In the hydrogenation reduction reaction, the conversion rate of raw materials and the selectivity of the catalyst are both important. In actual operation, How should we balance these two indicators? Or which indicator should we focus on more?”
“Neither conversion rate nor selectivity can be neglected, but in a sense, the selectivity of the catalyst is more important. For example, a certain catalyst has a high conversion rate of raw materials, but the selectivity is not good, even though the raw materials have been converted. , but what is obtained is not the target product, and it is meaningless no matter how high the conversion rate is, or even a waste of raw materials. Fortunately, the palladium carbon catalyst we use has a selectivity close to 100%, and the conversion rate can be controlled within an appropriate range."
"Since the catalyst selectivity is so good, why not pursue a higher conversion rate?" Guo Peng asked.
"This involves the philosophical issue of quantitative change and qualitative change. Under appropriate conversion rate conditions, the selectivity of the catalyst is close to 100%. If we must pursue a higher conversion rate, the reaction time will inevitably be extended. As the contact time of the materials increases, the catalyst As a result, the selectivity decreases and by-products gradually increase. Traditional Chinese culture advocates the golden mean and pursues the ultimate in everything, which will be accompanied by unexpected consequences."
It was originally a purely technical issue. When Fang Hanmin explained the technical reasons, he not only connected it with philosophy, but also added an understanding of traditional Chinese culture. Who can believe that the young deputy section chief in front of him is just a person with neither academic qualifications nor qualifications? ordinary worker?
Regarding the series of questions raised by Guo Peng, let alone old college students from Red Star Pharmaceutical Factory including Mr.
In his previous life, Fang Hanmin was an academic leader throughout his entire academic career. Although science was his main focus, he focused on improving his overall quality. From his undergraduate degree to his PhD at Oxford, his elective courses focused on literature, history and philosophy. He has always been involved, so he can interpret a purely technical issue from different angles.
Guo Peng stopped asking questions. He knew that his questions would not trouble Fang Hanmin. What neither he nor Xu Hui understood was that the person in front of him of the same age had either academic qualifications or qualifications. Where did this knowledge come from? of? After all, I was a top student in my studies back then, but now compared to others, there is a huge difference!
