Zhao Yuan saw Xu Qin in the office in the evening.
It had been a while since I had seen my senior sister, and Xu Qin had lost a lot of weight.
It's not that I'm sickly thin, but that through long-term fitness, my whole person's temperament has become more sunny and confident, and my body line has become smooth and soft.
Xu Qin took out a paper from his bag and handed it to Zhao Yuan.
"I discussed the idea you proposed last time with Master Zhu and then revised it. This is the final draft. Take a look at it. If there are no problems, I will submit it tomorrow."
Zhao Yuan took the manuscript in his hand and read it carefully. There were many changes. In addition to the core points, the entire structure was revised, which made it appear more professional and rigorous, and enhanced its persuasiveness.
Sometimes whether a paper can impress the judges depends on its rigor.
Zhao Yuan’s advantage lies in his forward thinking, but he wrote relatively few papers and the structure must be adjusted.
"It's very well written. Why didn't you and Master Zhu's names be signed?" Zhao Yuan was a little surprised.
Xu Qin said with a smile, "I just did the polishing work, the article doesn't have anything of mine in it. For Master Zhu, she thinks her participation in the entire article is too low. In addition, this is your first article Articles in foreign core journals signed with her name will reduce your contribution."
Zhao Yuan secretly thought that Zhu Haixia was careful enough.
Many tutors see the students below writing good papers and want to take advantage of them.
Zhu Haixia is obviously much more advanced, and she values the growth of her students more.
This paper by Zhao Yuan mainly describes CAR-T technology.
CAR-T is called chimeric antigen T cell immunotherapy.
By culturing T cells that can kill cancer cells in vitro, the T cells are infused
Returned to the patient's body to achieve therapeutic effect.
Clinically, this technology is used to treat blood diseases such as multiple myeloma, acute lymphoblastic leukemia, and refractory malignant lymphoma.
In addition, it also has certain therapeutic effects on some solid cancer diseases such as neuroblastoma and glioma.
This concept was proposed at the end of the last century, and its development process in this world is very slow.
If we count the time, in the past five years, there has been a major breakthrough in another world.
However, in this world, there has never been a breakthrough point.
Many blood teams across the country are working to capture the breakthrough.
This paper by Zhao Yuan mainly provides a breakthrough idea on how to prepare CAR-T cells on a large scale!
Currently, the cells approved for CAR-T cell therapy and used in clinical trials are all from autologous sources.
That is, T cells are collected from the patient, modified outside the body to recognize targets on the surface of cancer cells, and then reinjected into the patient.
However, this personalization process is complex, time-consuming and expensive, greatly limiting the number of patients who can benefit from CAR-T therapy.
In his paper, Zhao Yuan proposed using allogeneic cells to produce "off-the-shelf" CAR-T cells, eliminating the need for personalized preparation processes.
This enables ready-made cell therapies to be delivered to more patients faster, more reliably and at a larger scale.
To put it simply and straightforwardly.
In the laboratory, it has been proven that CAR-T can treat diseases, but it cannot be mass-produced.
Zhao Principle gave ideas for mass production.
To directly transform the theoretical knowledge in the laboratory into results, you can use
operate in the market.
It's like a serum for treating snake venom.
Initially in the laboratory, there was a way to create a one-to-one snake venom serum, but there was no way to create a serum that could treat many snake venoms.
The manufacturing cost of one-to-one snake venom serum is too high and cannot be mass-produced.
But with the advancement of technology, the laboratory has developed a serum that can treat many snake venoms, which can be mass-produced. Once produced, it will have market value.
Because Zhao Yuan knew that in another world, the mass production idea he proposed was feasible, he felt more confident in writing the paper.
When Xu Qin first came into contact with Zhao Yuan's idea, he was immediately shocked.
Zhao Yuan has only recently come into contact with the relevant knowledge of hematology.
Everyone knows that his advantage lies in clinical surgery.
Although hematology also involves surgery, it is completely different from the system that Zhao Yuan is good at.
Facts have proved that Zhao Yuan has extraordinary imagination and creativity in research on blood diseases.
Zhao Yuan’s entry point is linked to practicality.
This paper can provide accurate ideas to many teams.
Zhu Haixia already intends to carry out fruitful research on Zhao Yuan's point of view.
Zhao Yuan actually didn't have much confidence in this paper, mainly due to his lack of understanding of blood diseases.
However, with the improvement of Xu Qin and Zhu Haixia, the paper showed a unique effect.
Xu Qin said with a smile, "Master Zhu told me privately that with your thesis, you can directly graduate with a Ph.D."
Zhao Yuan was surprised, "Don't lie to me. Master Zhu is just giving me encouragement. Don't you still know what I have in my stomach?"
Xu Qin said in a sincere tone, "Don't be humble. I have only been in this field for more than a year."
With practice, I can write such an in-depth paper. To be honest, I am really a genius in scientific research. If you hadn't done a particularly good job in the surgery, Master Zhu would definitely drag you into the laboratory every day to squeeze more things out of your brain. "
Zhao Yuan's scalp went numb when he heard this, and he said with a guilty conscience, "I'm really not good at scientific research. Master Zhu must have noticed that I had a sudden flash of inspiration."
Xu Qin looked at Zhao Yuan with a smile, "By the way, I'm hungry."
Zhao Yuan patted his forehead and said, "I'll treat you to dinner! Tell me, what do you want to eat?"
Xu Qin frowned, "There is no sincerity at all. Do you know what is the most correct way to treat guests? You should not ask what to eat, but choose a place and take me directly."
Zhao Yuan laughed dumbly, "Let's eat our own food!"
Xu Qin stood up, her beautiful eyes moving, "Well, this attitude is pretty much the same."
Zhao Yuan didn't know where Senior Sister Xu was from, but he felt that Senior Sister Xu's temperament was like that of a girl from the south of the Yangtze River. She was somewhat refined and fashionable, soft on the outside but strong on the inside, and loved to compete in everything she did.
If you are in a relationship, this kind of personality is a must. If you make a small mistake, she will be in a cold war with you for half a month.
But when it comes to scientific research, this personality is very suitable. When encountering tough problems, you will have enough toughness.
Xu Qin's personality is similar to Zhu Haixia's when they were young, so they have a very good relationship, not only as master and apprentice, but more like mother and daughter.
The decoration of the restaurant is good, and with the elegant melody, it feels like being on the Bund.
The vegetables are stir-fried in a light and refreshing way, and the fish is cooked in heavy oil and red sauce.
Halfway through the meal, Xu Qin finally explained another reason for looking for Zhao Yuan.
"Junior brother, I have something to ask you for help."
Zhao Yuan put down his chopsticks and said with a smile, "It's your business."
, it’s my business, no need to be polite, just give me orders! "
