Parkinson's disease is a common degenerative disease of the nervous system that mostly occurs in the elderly, with the average age of onset being around 60 years old.
As industry experts, Li Weijian and others understand that the prevalence of this disease in Daxia is extremely frightening. The approximate probability of people over 65 years old suffering from this disease in Daxia is 1.7%...
An expert from Xishu and West China frowned and said: "The main pathological change of Parkinson's disease is the degeneration and death of dopaminergic neurons in the substantia nigra of the midbrain, which results in a significant reduction in DA content in the striatum and Pathogenic.
At present, major research institutions at home and abroad have not grasped the exact cause of this pathological change. However, based on clinical cases and years of analysis, most of us believe that this disease is related to genetic factors, environmental factors, aging, oxidative stress, etc. May be involved in the degeneration and death process of PD dopaminergic neurons. "
"Brain trauma, smoking and other factors may also increase the probability. However, at our previous research conference, most data showed that smoking is negatively correlated with the probability of getting this disease." An expert from Yanjing added.
"Yes, if the patient cannot control the symptoms through medication and psychological treatment, we need to consider DBS surgery, deep brain stimulation, and destruction of the globus pallidus or subthalamic nucleus to relieve symptoms."
A group of experts discussed with serious expressions. If Gu Qing and others were patients, they would probably be half-hearted.
Unfortunately there is no if.
Professor Chen held the scrutinizing gaze of these industry leaders, nodded slightly to Gu Qing, and then said in a calm voice: "Yes, Parkinson's disease is a long-standing problem. The Global Burden of Disease Research Report once pointed out that our country has The number of Parkinson's disease patients in China accounts for about 23% of the global Parkinson's disease population. According to model projections, by 2030, it is very likely that about half of the world's patients with the disease will be middle-aged and elderly people in China.
And in addition to tremors, another important symptom of Parkinson's disease is slowness of movement. In the late stages of Parkinson's disease, due to the inexorable loss of dopamine-releasing neurons, the drug levodopa becomes less effective in treating symptoms.
And our starting point is not medicine.
In a paper report in the journal Nature, foreign scientists discovered that by selectively destroying the function of mitochondrial complexes in dopaminergic neurons in mice, they found that the dysfunction was sufficient to cause progressive Parkinson's disease-related motor deficits, and was different. Correlation between types of motor function impairment and dopamine release at different sites.
This discovery gives us a breakthrough in our research.
Together with other departments, while sharing resources, we will conduct more in-depth research on the neural transmission mechanism and the sensitivity of animal and human nerves to equipment, coordination frequency, and synchronization of some confidential data.
Our Applied Neurotechnology Laboratory of the Institute of Brain Science had some special achievements three years ago. In recent years, thanks to the sharing of resources from several major projects of the company, we have achieved minimally invasive implantation of brain-computer interfaces, allowing patients to It can communicate stably even if you have hemiplegia or Parkinson's disease.
Even if the patient's special nerve activity is high enough and the patient's physical fitness can support the operation, then we can perform more advanced treatments and replace the necrotic parts with mechanical parts. "
Professor Chen's calmness surprised all the medical leaders.
What is this kid talking about? Are you ready for surgery?
Three years? Such rapid progress?
"I have been paying attention to this field, why haven't I seen your application documents?"
A professor with a stern expression walked quickly to Professor Chen and asked in a questioning tone.
When hospitals conduct certain clinical medical experiments, they need to submit all clinical plans including preclinical test materials, planned test sites, sponsors, instructions for conducting clinical trials, all conditions found in animal tests, etc. to the official agency. It must be reviewed and approved by the Institutional Review Board, and the progress and results of the clinical trial must be reported to the official agency once a year.
The professor who asked this question is not only a medical expert at the Medical University, but also works in related institutions.
Therefore, when this kind of problem occurs in his field, his first reaction is to get to the bottom of it.
Professor Chen looked at the old teacher walking towards him. The menacing look on the old teacher looked like two different people from the one who used to teach in the department.
However, he did not back down, but explained very naturally: "Our clinical trials are all conducted under the full supervision of special departments, and these documents do not need to pass normal agency review.
If you have any objections, you can use your own authority channels to learn about the specific situation.
Of course, my personal suggestion is that you'd better investigate the specifics of this project in a safe environment, because this project is still under extremely high confidentiality for the time being. "
This set of words immediately tied the old professor to the spot.
Then Professor Chen, the head of the laboratory, continued: "Next we can see a patient with advanced Parkinson's disease who has been treated by us. He has been diagnosed and treated at the Medical University Affiliated and West China, so some of you should be familiar with it. He still has an impression."
Seeing that Professor Chen had been able to guide these great masters in the medical field in Daxia, Gu Qing retired with confidence.
At present, the brain-computer interface of the Applied Neurotechnology Laboratory of the Institute of Brain Science can display quite a few functions for this part. In addition to decoding working memory, emotion and movement integration, it can also provide feedback through special nerves. , perform adaptive adjustment and sensory feedback to achieve stable improvement of brain function.
After the survey, will these professors ask the classic question "If neurotechnology can decode consciousness and two-way regulation, is it possible to intervene and change people's free will in the future?"
Gu Qing didn't intend to continue arguing with them.
After all, the clinical application of this innovative neurotechnology in neurosurgery will not only bring about these problems, but more importantly, it will save lives and heal the wounded, giving those who desperately desire health and freedom a better future.
In this case, whoever dares to block the implementation of the technology will become the mortal enemy of all patients who pursue a better life.
Even if this person is a Western leftist or a top player in some industry...
In the following days, this group of research teams composed of professors from major top hospitals, from the initial surprise and discomfort, gradually began to catch up in a very short period of time.
I get up at 6:30 every day, and at 7:30, I start to learn about the application and development of technology under the leadership of several leaders in the laboratory. In the afternoon, I start to read a medical book and a brief research report. They study harder than senior high school students until late at night.
Then he went to the cafeteria to finish dinner, and then continued to study overtime voluntarily.
During this period, Li Weijian, as a prominent figure and senior figure who established the first multidisciplinary ischemic cerebrovascular disease treatment team in China, had already learned about Professor Chen, the head of the Applied Neurotechnology Laboratory, through communication identity of.
Chen Qinghai, one of his favorite students many years ago, but this student became invisible after entering a major hospital and experiencing some dirty things.
Now it seems that this student is indeed better than his predecessor, and he is doing very well in Jiuzhou Science and Technology.
Li Weijian also realized later why he had not contacted this student when he was looking for him in the past two years.
The results of these trillion-dollar investment projects of the Jiuzhou Science and Technology Titanium Star Department, even if they are said to be shared, cannot really be taken for free. The extremely strict confidentiality work must be stricter than that of my old army.
However, as the investigation deepened, even though Li Weijian considered himself a materialist warrior who was enlightened and had seen strong winds and waves, he still felt emotional many times.
"Why is Jiuzhou Technology so focused on these experimental projects? The results of projects worth trillions of investments not only share data, but also share R&D personnel.
Those teams of scientists and engineers can create huge value even if they focus on one project for a week, but how high is the cost of doing so?
Moreover, the semiconductor department of Jiuzhou Technology will actually customize the chip price, system architecture, and algorithm for a small experimental chip. "
In the dead of night, Li Weijian closed his eyes and counted what he had seen and heard recently. He felt that Jiuzhou Technology was not like a private enterprise pursuing profit at all, but more like the great projects he had treated. The unit to which the soldiers belong.
The young man named Gu has unknowingly mastered huge resources that ordinary developed Guo Jia does not have.
Tens of thousands of graduate students, engineers, scientists, and an unknown number of trillions of project resources are all under the management of this young man, and are reasonably arranged and coordinated.
In the military field, such people are generally handsome talents that are rare to see in thousands of years.
Li Weijian's emotion gave him the urge to write a separate investigation report on Gu Qing after the mission.
It stands to reason that apart from him, a large number of people in the officially organized research team have this idea.
What's more, some already want to resign from their original employer and join Jiuzhou Technology Company.
It’s hard not to be attracted by this kind of scientific research environment with massive resources, responsiveness, and simple interpersonal interactions.
When people are immersed in something, they will ignore the passage of time.
November 29th suddenly arrived.
On this day, Li Weijian got up early. At noon at five o'clock in the morning, he had already gone to the laboratory base to check medical and research reports.
But when he just finished eating two steamed buns, changed into his lab coat and entered the core laboratory of the experimental base, he found that his student was already busy on the workbench.
Judging from the working status of the assistants beside him, they should have been working for a while.
Li Weijian did not disturb the other party's work. He stood outside the isolation window like a student, watching Chen Qinghai's every move with concentration.
Twenty years ago, he was a teacher, imparting knowledge without reservation on the podium and in the ward.
Twenty years later, he is a student, studying and exploring seriously outside the laboratory.
This morning self-study started very early, but there were not many students coming.
Daxia Junfang General Hospital, Neurological Medicine Research Institute of a hospital affiliated to Yanjing Medical University, the First Affiliated Hospital of Daxia Medical University, Tongji University Affiliated Hospital, Fudan University Affiliated Hospital, West China Hospital of Xishu University and other hospitals and institutions The experts came to this experimental base very early as if they had made an appointment.
As usual, they were in the observation room observing the operations and experiments that the laboratory could display to the outside world.
This was followed by the exploration of pharmaceutical medicine, the study of biological nerve signal transmission, and the working principle of neural converters.
It's just that they didn't go to the cafeteria to eat at meal time as usual. They just ate some compressed biscuits at noon and continued to study non-stop.
Even if they learned the programming knowledge of Kyushu compiler in the afternoon...
But as one of the basic knowledge of Kyushu Technology's neural application technology, these old men and women are still unwilling to let go of any learning opportunities.
It wasn't until the sun finally set that the official staff who had accompanied them throughout the whole process informed these old students with a blank face to pack their luggage, sort out their materials, and go to another place for the next mission.
In fact, no official staff needed to tell Li Weijian that the next task would not be easy.
But when he was drafting the manuscript, every time he summarized a knowledge point, he would feel a sense of emotion.
This former student of mine is already too far ahead in the professional field. If we follow their research and development ideas, in the future, humans may really be able to achieve immortality in their bodies even if their consciousness does not die.
Other medical professors also had similar sentiments.
So a few days later, a bunch of research reports that attracted the attention of countless people, but were destined to be seen by only a few people, were presented to a few people.
"Research Report on the Latest Scientific Research Results of the Applied Neurotechnology Laboratory of the Jiuzhou Institute of Science and Technology Brain Science"
The name of this report is the most normal, but it has not been placed at the top because the person who wrote this report has little experience and is not a professional. He is just someone placed by the government with this knowledge and experience. senior staff.
The top document bag contained Li Weijian's investigation report.
A pair of hands took it out and placed it on the head of the eucalyptus.
He opened it calmly and turned to the first page of the report. The text that came into view made this man's hand tremble subconsciously.
Of course, this is not an attack of Parkinson's disease, but a manifestation of subconscious shock to one's own nerves.
"Feasibility Investigation Report on the Human Immortality Project"
These words made this person's breathing become tense.
