After hearing Yang Fan's words, everyone couldn't help but nodded.
Yang Fan is right. Indeed, this is an issue that deserves great attention and is also a key to measuring the value of this project.
Otherwise, even if research makes progress and they successfully cultivate viruses or bacteria specifically targeting Helicobacter pylori in the stomach, they will not be able to be put into clinical treatment, let alone marketed.
So everyone couldn't help but turn to look at Fang Renzheng, waiting for his answer.
Fang Renzheng smiled and nodded when he heard this: "Your concern is right, this is indeed an important problem we face during the entire project research process.
In this project, we actually faced many problems.
For example, when choosing which phage to choose, there are many types of phages, from T1, T2, to T3, T4, T5 and so on. We must find an ideal phage.
Then, targeted culture is performed to change the target of attack, from the original bacteria to Helicobacter pylori in the stomach.
This is just the first step. Then we need to stabilize the superphage we cultured against Helicobacter pylori in the stomach so that it has stable DNA.
Therefore, it is not easy to cause mutation in the process of many reproduction splits, or even eliminate mutation. Even if it mutates, its variants will not cause harm to the human body.
In layman's terms, we need to cultivate a new type of super phage that specifically targets Helicobacter pylori in the stomach. This phage specifically targets Helicobacter pylori in the stomach.
If the Helicobacter pylori in the stomach is completely eliminated, then the Helicobacter pylori in the stomach will die quickly after losing its ability to attack its parasitic target, and will be excreted through human metabolism.
And this new type of super phage is safe enough. It will only attack Helicobacter pylori in the stomach, not other bacteria, let alone human cells and tissues.
During the process of reproduction, mutation will not occur, or it is not easy to mutate, and even if it mutates, it will not cause harm to the human body. "
After hearing Fang Renzheng's introduction, everyone couldn't help but nodded, agreeing with his statement.
Seeing this, Fang Renzheng smiled slightly, and then continued: "At present, we have found a suitable phage, and after cultivating and inducing it, we successfully changed its attack target and then attacked Helicobacter pylori in the stomach.
Please take a look, this is our relevant experimental picture. "
Under Fang Renzheng's guidance, everyone looked at the big screen in front of them. Relevant experimental pictures were immediately played on the big screen. Some were electron microscope pictures, and some were demonstration videos.
Through the electron microscope picture, you can see that in the petri dish, a dropper dropped a drop of light blue liquid into the petri dish, and then the electron microscope magnified the magnification. I saw that among these blue liquids were some strange-looking, even scary viruses, or phages that were spreading out very actively and rapidly.
These phages spread out in the petri dish and quickly attacked the Helicobacter pylori in the stomach. It was seen that these new super phages, after contacting the Helicobacter pylori in the stomach, quickly grabbed the Helicobacter pylori cells in the stomach, and then inserted the very sharp needle into the bacteria.
Then after a while, the Helicobacter pylori in the stomach ruptured, and many new, slightly smaller superphages poured out. These phages wander around looking for new H. pylori bacteria in the stomach.
Fang Renzheng showed a proud look to everyone, and then introduced with a smile: "This is the new super phage we have cultured. What you see is this new super phage attacking the electrons of Helicobacter pylori in the stomach in a petri dish. Microscope picture.
In order to facilitate viewing, we have fast-forwarded the video screen, which is not so fast under normal circumstances.
As you can see, with the passage of time, these new super phages have attacked and eliminated all Helicobacter pylori in the stomach in the entire petri dish.
In addition to gastric Helicobacter pylori, we also placed other bacteria in the petri dish, such as Escherichia coli, Lactobacillus, Bifidobacterium, Bacteroides, Peptostreptococcus, Veillonella, etc.
As you can see, most of these other bacteria are alive. In other words, while our new super phage attacks Helicobacter pylori in the stomach, it does not attack other bacteria.
Even after all Helicobacter pylori in the stomach were eliminated, these new super phages that multiplied in large numbers lost their target and began to die rapidly without attacking other bacteria. "
After hearing Fang Renzheng's introduction, everyone couldn't help but nodded, and Wu Hao and Yang Fan also smiled.
Well done, it's really remarkable that you have achieved such great results in such a short period of time. Wu Hao praised.
Thank you for the compliment. Fang Renzheng thanked him with a smile, and then smiled at Wu Hao and said: "Actually, this experiment is not perfect. During the monitoring process, we also discovered that new super phages attack other bacteria, but the proportion is relatively small.
In addition, we also discovered that the new superphage mutated during its reproduction.
Therefore, for us, this is just the first step in a long journey, and we are still far from actually entering clinical trials. "
Wu Hao heard this and waved his hands with a smile: "Don't be in a hurry, don't be in a hurry, take your time, I believe you will be able to complete it, and this is already a very remarkable achievement in itself.
How's it going? Have you written the paper? "
Fang Renzheng smiled and shook his head: "I have been busy with experiments these days and have no time to write a paper."
Wu Hao heard this and shook his head with a smile: "That's not okay. I'm busy with experiments, so I can't forget to write a paper. And the paper itself is also a kind of work. This is also your academic achievement, and it should be recognized by the entire academic community. Know.
Take the time to write it and publish it as soon as possible to let the whole world know about our great achievements in this field. "
Speaking of this, Wu Hao softened his tone and said: "And you have to understand that this kind of important results should be done sooner rather than later. If it is leaked and published by others first, it will be very important to you, your entire project team, and the company." loss."
I understand, I will definitely start writing the paper as soon as possible and strive to publish it as soon as possible. Fang Renzheng nodded.
Hearing Fang Renzheng's words, Qin Yongchuan showed a happy smile: "That's right, I asked you to do it before, but if you didn't do it, you said it would affect the research work.
Now that Mr. Wu has told you, you must take it seriously.
This is not only about your personal gains and losses, but also about the interests of your entire team and even the entire company.
So you must take it seriously and not be careless. "
