"Oh, this is a good research topic." Wu Hao's eyes lit up when he heard this, and he couldn't help but admire it.
"So, you have achieved good results in this regard."
"Yes." Fang Renzheng nodded: "If there is a safer and faster treatment method, then we will save countless patients suffering from Helicobacter pylori infection. For this alone, I think there is hope Fight for the Nobel Prize.
Even if it cannot be obtained, this is a medical achievement that is enough to make all mankind excited.
Compared with its meaning, its economic value is more significant. If we develop this specific drug, it will mean that we directly or indirectly eliminate the common drugs and therapies currently on the market for gastric Helicobacter pylori infection.
With such a large number of infected people in the world, the value of this drug and therapy patent alone is already an immeasurable figure. "
Hearing Fang Renzheng's words, Wu Hao shook his head and said: "Although that is said, it is probably very difficult to develop such a specific drug. You have to know that all the major pharmaceutical giants now have plans in this field. Research.
Compared with these pharmaceutical giants, we are still just a fledgling small workshop. "
Fang Renzheng nodded and said: "Of course we know the gap between us and these pharmaceutical giants and top laboratory research teams.
However, in fact, the research in this field is basically the same, and there are no major breakthroughs. What everyone is currently studying is how to use specific drugs to directly kill Helicobacter pylori.
Although this method is direct, it is very violent. Not only is it powerful, but it can also easily harm innocent people.
So we were wondering if there was a drug specifically targeting Helicobacter pylori in the stomach. "
At this point, Fang Renzheng laughed: "Don't tell me, after careful verification, we found that there is indeed one.
This is a small molecule compound zinc linolenate developed by a team of experts and professors from Shicheng Medical University. It is said that it specifically targets Helicobacter pylori in the stomach and has good effects.
Although relevant papers have been published for several years, the drug has not yet been put into use. And there is no real report on its reliability and safety so far.
In our opinion, this small molecule compound zinc linolenate is still a chemical substance and has not yet come out of the traditional theoretical thinking system.
How to find another way to find a safer and more effective removal treatment method is a question that has been explored and researched. "
Having said this, Fang Renzheng led Wu Hao and the others into a brightly lit demonstration hall, and then continued to introduce to Wu Hao and the others.
Just when our research was at an impasse and there was no progress, a short popular science video and article inspired us, or gave us an instant inspiration.
"This is a video introducing T2 phage."
"T2 bacteriophage?" Upon hearing this name, everyone present couldn't help but become curious.
"Yes, T2 phage, which is a strain of phage, belongs to the T-series phage. It is a virus that specializes in parasitizing bacteria.
It looks like a tadpole, with an icosahedral head, a shell made of protein, and DNA wrapped in the head as genetic material. Because its appearance is so special and very different from the bacteria and viruses we see, this T2 phage was once suspected by many people to be an alien life that invaded the earth.
When it infects the host, the tail sheath shrinks, and the DNA from the head is injected into the cell through the hollow tail, thereby synthesizing progeny phages through the materials in the host.
One characteristic of this T2 phage is that it specifically selects to parasitize E. coli and reproduces very quickly.
It will actively search for the location of E. coli and actively attack. After infecting E. coli, it will use the substances in the E. coli body to synthesize its own components under the influence of its own genetic material and multiply in large quantities.
When the phages proliferate to a certain number, E. coli lyses and releases a large number of phages, which are potent phages.
Therefore, many scientists are now studying this T2 phage, hoping to use it to treat some cases of E. coli infection. "
Having said this, Fang Renzheng smiled and said, "However, we have seen infinite possibilities in it, or we have been inspired.
So, can we also cultivate such a bacteria, or virus, that specifically targets Helicobacter pylori in the stomach to kill Helicobacter pylori in the stomach?
Our research has always been limited by our own thinking, why can't we jump out and see.
Helicobacter pylori in the stomach is a kind of bacteria, so why can't we use bacteria to fight bacteria and viruses to fight viruses. "
"Use bacteria to fight bacteria, and use viruses to fight viruses. To put it bluntly, it is bacterial warfare and virus warfare in war." Wu Hao said with a smile: "It's just that you used them in the human body and transformed people into human beings." The body is treated as a battlefield.”
"You're right."
Fang Renzheng nodded: "Since animals in nature have natural enemies, don't these bacteria and viruses have natural enemies?
In this case, why don't we use their natural enemies to deal with these bacteria and viruses. Wouldn't this be greener, safer, and more effective?
In this case, why do we need to use these chemical pharmaceutical ingredients.
Our ancestors all said that medicine is three parts poison. This kind of chemical drug, even if the side effects are small, will still have side effects, which is a kind of harm and potential threat to human health.
The natural enemies of this bacteria are viruses and bacteria. They are specifically fed with bacteria and are not harmful to the human body. It can be said to be a safer and greener treatment method. "
Hearing Fang Renzheng's answer, Yang Fan couldn't help but shook his head: "The natural enemies you mentioned that kill bacteria are either bacteria or viruses.
So how do you ensure that these natural enemies and bacteria are safe and reliable enough so that they can attack harmful bacteria without causing harm to the human body.
If these bacterial viruses evolve or mutate and change their attack targets, wouldn't they cause more serious harm to the human body?
You have to know that bacteria are prokaryotes, and their DNA lacks nuclear membrane protection compared to eukaryotes, so it is more susceptible to damage and mutation.
Moreover, bacteria reproduce very quickly, and one generation can usually be produced in 20 minutes. If conditions are right, one bacterium can multiply into hundreds of billions in a day and night.
With such a high reproduction rate, DNA molecules must be copied every time they reproduce, so replication errors are more likely to occur, which greatly increases the chance of mutation.
In this way, who can guarantee that these bacteria or viruses will change the characteristics of these bacteria during the process of reproduction and mutation, causing them to change their attack targets and choose to attack other bacteria or even human body parts.
There is no effective way to target such mutated bacteria and viruses, which will cause greater harm to the human body. "
