"You are still young now. You have just entered the door of scientific research, and you are already involved in such a cutting-edge project. This is your luck and your misfortune."
"Soon you will discover the truth of scientific research."
"And I will also show you the most important thing in becoming a true scientist."
The more Huang Qin talked, the more excited he became, and his tone became extremely passionate.
"That is, the inner love for scientific research and the strong interest in exploring the unknown world."
"Scientific research is about exploring the unknown world and making scientific discoveries. There are no books to look up the answers. It's all up to you to explore in the dark and try one possible path after another."
"You have been stuck in the fog of the unknown world for a long time, and you can only rely on your intuition to find the right way out."
"You will be afraid, you will be confused, but your firm heart and eternal love will become the brightest light in the fog, illuminating your way forward."
After hearing this, everyone was silent for a long time.
After a long time, a burst of thunderous applause broke out.
Suddenly, the laboratory door creaked.
Instructor Du Biao pushed open the door and looked at everyone with a blank expression.
"What are you doing? Why is it so lively?"
He was shocked when he saw his students were all excited, their eyes glowing green, and they looked like they were following a pyramid scheme.
"Teacher Du, are you back?"
The students all turned around and looked at him with bright eyes, as if they were looking at a paper gift package.
"What's going on? I'm a little scared when you guys are like this."
Du Biao put down the briefcase in his hand and hung his coat on the hanger with a surprised expression.
Huang Qin couldn't help laughing when he saw the teacher like this.
"Teacher Du, don't be afraid. It's absolutely good news. They just found out that their paper was published, so they are all happy."
"Young people are a little excited when they publish their first paper, which is understandable."
"What? They published all eight papers? There were no rejections?"
Now Du Biao was ecstatic. He rushed into the crowd and urged.
"Quickly, take out all the emails. I want to see for myself how the reviewers responded."
"Have you pointed out any errors and suggested any corrections?"
Du Biao picked up the students' mobile phones one by one, carefully read the reply emails, and immediately beamed with joy.
"Not bad. They are all core journals, and there are three SCI area two articles. They are almost catching up with me, teacher."
"I passed it straight away without even asking you to make a small repair?"
"Haha, it seems that my manuscript review skills are still young."
"Good, good. Now you finally have a thesis. You don't have to worry about graduation. Next, you must guard against arrogance and impatience, continue to work hard, and complete the project as soon as possible before graduation."
He touched his chin and couldn't help but feel complacent, and at the same time he didn't forget to spur the students.
Huang Qin said quickly: "Don't worry, I just assigned them another task. They will be busy in the next few months."
"Everyone needs to write at least four more papers to be worthy of your teachings."
Du Biao's eyes widened instantly: "No, four articles per person? Is it such a heavy workload? Isn't it too tiring?"
Unexpectedly, the students all shook their heads at the same time, as if they were swaying with a rattle.
"I'm not tired, I'm not tired. I'm working with my teacher and senior brother. I feel comfortable. I'm not tired at all."
Du Biao suddenly became speechless and swallowed back the words "Do you want to take a few days off?"
He waved his hand as if resigned to his fate.
"That's alright, you can just give me whatever you want. Don't ask for too much. Journals from the third and fourth districts are fine, as long as they can be distributed."
"Anyway, Huang Qin is watching in the laboratory, so I feel relieved."
"I'm going on a business trip to Haishi in the afternoon to attend a biology academic conference at Jiaotong University. It may take three days to come back."
"This conference is very important. The special guests include Academician Chang Sanwei and several leading figures in cell biology. I have to go and get familiar with it and get to know a few more big names."
“If you have any questions, feel free to ask me on WeChat.”
Huang Qin immediately cast an appreciative look: "Teacher, you learn very quickly. You have already started running for outstanding students."
"You really need to get to know more big shots. When the time comes to vote for you, you have to rely on them."
"The field of xenogeneic organ transplantation is still very unpopular in China. As long as you talk about our project, it will definitely leave a deep impression on the bosses."
"Teacher, as the hope of the whole village, you have to stand up. Our laboratory relies on you to go out and become famous socially."
Du Biao smiled awkwardly: "Am I that important? Why didn't I feel it?"
"I'm out here every day, either attending meetings in the hospital or participating in various academic conferences. I don't have much time to do research. I don't know if it's a good thing or a bad thing."
"Don't let your reputation be ruined by then. It's better not to do it."
Huang Qin consoled him: "Teacher, you were just a nobody before, how could you have any reputation?"
"You know, writing articles takes more time than poetry, and doing scientific research is the same."
"If you are selected as an outstanding youth, we will be proud of it. When we graduate and go out to find jobs, everyone will look down upon us."
"This situation is only temporary. Anyway, you have no hope of academicians and Yangtze River. From now on, you will have no desires and desires. You can concentrate on the research you like."
When he heard these words, Du Biao couldn't help but twitch the corner of his mouth and could only show a wry smile.
"It's strange that you think so highly of me."
Outstanding Youth, Outstanding Youth, although everyone said that the project he was working on was very cutting-edge and very sophisticated, as long as he produced results, he had a high chance of being rated high.
But he was still a little unsure. After all, he didn't know what others really thought, but he knew his true abilities very well.
If Huang Qin hadn't brought money to join the group, given research directions, and designed various experiments.
He would never be able to make such a big fuss, and he would have no shame in going to an academic conference to eat and drink.
He knew very well that he could hold such a large project, talk nonsense at various meetings, and receive a large number of unidentified admiring glances from his colleagues.
It’s all driven by the students!
If a disciple is like this, what more can a master ask for?
When Du Biao thought of this, he nodded gratefully and showed a kind smile.
"Since you said so, I will definitely not let you down as a teacher."
"You guys have a good job in the lab and I won't disturb you anymore. I have a meeting at one o'clock in the afternoon and I have to leave now."
Everyone applauded to see the teacher off. The atmosphere was so warm and the words were so heart-warming, it was like seeing off the teacher on the battlefield.
"Teacher, you must live up to your expectations."
"Teacher, you are not a good drinker. I have prepared anti-alcohol medicine here. Remember to take some with you."
"Teacher, get to know more people and wait until you come back to chat with us about academician gossip."
"Teacher, you must perform well in the afternoon meeting."
Du Biao scratched his head, feeling that something was wrong, but he didn't say much.
In this way, everyone sent Du Biao out of the laboratory with sincere expressions and enthusiasm.
Then, the next round of water thesis began.
With this first experience, everyone got started quickly.
The current gene editing technology is so simple that even high school students can do it, so it is no problem for them.
The students skillfully removed the relevant genome from the pig cells and transferred it into the corresponding humanized genome.
It is then fused with pig egg cells that have had their nuclei removed.
The fertilization process of mammals in nature is actually just to provide chromosomes for egg cells.
Because there are only half the number of chromosomes in the egg cell, it cannot make up for itself.
All chromosomes need to be supplemented through fertilization in order to divide and develop into a normal fetus.
When the egg cell's nucleus is removed, the nucleus of an adult cell with all of its chromosomes is implanted.
Then, no fertilization is required, it also has all the chromosomes complemented and can develop into a normal embryo.
This is the clone.
This technology of mature cell nuclei + egg cells is also called cloning technology and is widely used in various cloned animals.
However, they do not need to actually clone the pig. They just develop the egg cell into a blastocyst and observe the physical development of the genetically modified pig embryo.
In about a few weeks, after the observation is completed, the pig embryos will be destroyed directly.
On the one hand, it is to study the expression levels of relevant signaling molecules during the development of pig fetuses. On the other hand, it is to see whether the pigs can develop normally and whether there will be any malformations or mutations after gene knockout or introduction of humanized genes.
This will lay an experimental foundation for the subsequent construction of a genetically modified pig model, and provide a certain theoretical basis for regenerating humanized organs in pigs in the future.
Once the entire process is recorded, and with appropriate language modifications, a good paper can be produced.
In fact, this is not really a water thesis.
At least the students have done experiments and provided real experimental data.
Future research on xenotransplantation will also be helpful.
It's just that they were all single-genome experiments, and limited by their level, there was no in-depth discussion of the principles behind them, and no more complex multi-genome models were established.
So it seems to be of average quality and a bit watery.
The most important reason is that they publish too many papers.
Of course, those more difficult and complex studies belong to Huang Qin's work, but he needs more basic experimental data before he can proceed to the next step.
Since each of the previous 8 papers only had one to his name, they didn’t seem very conspicuous.
However, after another period of research, everyone’s papers began to pour out.
More than 30 papers flew in all directions like snowflakes.
It quickly passed the review and began to be officially published in major journals.
Half of them were published in the three area journals dedicated to novices, with an impact factor of only a few tenths, and basically no one read them.
Only some papers published in Zone 2 journals, with impact factors between 1 and 5, can attract some attention and may be cited, but that's it.
However, Huang Qin's subsequent research was based on these seemingly very basic papers, and even required a lot of citations.
These 'water' papers are like inconspicuous bricks and stones, supporting the high-rise buildings he studies.
His research is very groundbreaking for the nascent field of xenogeneic organ transplantation in China and is absolutely at the leading international level.
Of course, the specific step he can reach depends on his final results.
If you just transplant the organs of genetically modified pigs into baboons, there have been many studies abroad, and the survival rate is relatively high.
There are very few research institutions in China, not to mention none.
Just making a breakthrough in this area is enough to take Du Biao away and make him an outstanding young man.
The main reason is that there are too few people studying this area and no one is taking advantage of it. As long as Du Biao has some achievements, he can take advantage of it.
If he can conduct further research and transform pig organs that are completely harmless to the human body, he will still be considered a master and a leader in this field.
If the usability of genetically modified pig organs in the human body can be confirmed, even if the external dialysis is successful or the internal transplantation survives for a period of time, it will be regarded as a great innovation. It will belong to the founder of the sect and is definitely expected to become an academician.
As for combining stem cell research, we can actually develop pig heart and human kidney, and then transplant the human kidney to the patient to make the patient survive.
That was definitely the second revolution in organ transplantation. It was groundbreaking in this field and can be called the founder of it.
Punching the Chinese Academy of Sciences and kicking the Nobel Prize are nothing more than that.
When I walked to the academic conference, the academicians rushed to greet each other as brothers and sisters, the Yangtze River scholars toasted and carried their bags, and the outstanding young people directly kowtowed to become their disciples.
There is no way, a brand new research field is so arrogant, flowing with milk and honey, and it is in urgent need of geniuses to open up new territories, and the rewards will naturally be extremely generous.
If the field of scientific research is red in the sunset, there are carrot pits filled everywhere, and there are several academicians guarding the top of the avenue, leaving only a few small pits for the descendants of the family. Naturally, there will be no way for people to rise in the future.
****
At the same time, the well-known domestic social platform, Bihu.
A question suddenly popped up, attracted a lot of attention, and quickly hit the hot list.
"What do you think about Professor Du Biao of Suzhou University publishing more than 40 SCI papers in half a year?" 》
"Recently, I discovered a strange professor, Associate Professor Du Biao of Suzhou University. He published more than 40 papers in half a year, all of which were listed as corresponding authors. Although the first author was someone else, it was obvious that he was very involved. Shen, what is going on? What do you think?"
The comments below were mixed with a mixture of indignation and ridicule.
"Is this the legendary Buffalo Boss? Why do you publish low-quality similar papers from the second and third districts?"
"On average, it takes four and a half days to publish a paper? When does scientific research stop?"
"Don't you know? Biochemical environmental materials are so easy to dissolve, haha."
"Am I the only one who thinks this professor is pretty good? At least he didn't steal students' research results."
"It's normal for him to be the corresponding author only. Maybe he has accepted more than 20 students, and each of them has written two papers. What's wrong? Are you still not allowed to do scientific research? The scientific research dog is so angry."
"It seems that Professor Du's students are under a lot of pressure on their graduation thesis."
"I dug out all the papers written by Professor Du. They are all about research on genetically modified pig cell models. One gene can write an article, which is crazy."
"It's like adding chicken poop to graphene to prove that it can conduct electricity."
"Don't slander Professor Du. He is determined to attack outstanding young people."
"Isn't that right, relying on the Water Road to attack outstanding young people? Why didn't you say that he was going to attack academicians?"
"If such a person can be rated as an outstanding young person, our country's scientific research will be really hopeless."
"I don't want to search them one by one. It's disgusting. He published so many papers and spent hundreds of thousands on page fees. He is really rich. Who is paying for it?"
"Susu University is also a 211 after all. Are all the professors there like this?"
"I really want to ask him face to face how he cultivated so many liar students and received so much national project research funding?"
"A scientific researcher should also have a sense of social responsibility and do things that are more meaningful to society. From the titles of these papers, I can't see how in-depth research he has done and how forward-looking he is. It's all meaningless. They are pouring water, wasting the country’s money, and taking advantage of opportunities!”
"Huo Huo, this topic is so popular. Let's wait and see whether the academic flood can escape the academic world."
"There are also professors abroad who publish more than 100 papers a year, oh, more than 100 papers. What's so strange about this? Academic circles around the world are not very clean, let alone the second brother."
"I told you to stop scolding. You are scolding because it feels good. What should students do if they graduate without a thesis?"
"We are all scientific research dogs. You don't want to be stuck on a thesis after graduation, right?"
"That is, graduate students only write papers to meet graduation standards. What level of journal can you expect them to publish in? "Nature"? "Cell"? Or "Life"?"
"As long as this requirement remains unchanged, graduate students will continue to struggle to write thesis. This is the current situation of domestic scientific research."
"There are many academicians and Yangtze River bosses who have the ability to do more than Du Biao. They stare at a young teacher who thinks about his students every day. Isn't it interesting to pick on the weak?"
…
There was a heated discussion on the Internet. Du Biao never expected that he would become popular from another angle and become a well-known 'buffalo' professor on the Internet.
Netizens have polarized views on him. Those in the scientific research circle feel that a person who can make students succeed in their thesis is undoubtedly a good tutor. Some postgraduate students are quite interested and even have the idea of enrolling him as a graduate student.
Outsiders were scolding him, accusing him of wasting taxpayers' money and squandering national scientific research funds.
Such enthusiasm even alarmed Dean Lu.
