"After the rabbit experiment was a great success, my senior brother was very confident. After preparing for a while, he called me over again and started the production of human organs."
"However, the scaffolds we used for growth at that time were not artificial, but were harvested from donated organs, using a mild detergent that cleans the donor stems that does not damage the extracellular matrix. , but all the donor cells can be removed.”
"After two weeks, what's left is a collagen scaffold of an organ, onto which we implant cultured cells taken from the patient, first smooth muscle cells and then endothelial cells, which line up to form blood vessels. "
"It took several months to cultivate the cells, and then experienced several failures. In total, it took more than a year to create the main body of the human organ under laboratory conditions."
"In addition, cultured patient skin cells were used as the outer skin, and veins harvested from the thigh were used to replace the urethra."
"The final product is very complete and has everything it needs, but the size is relatively mini, about the size of a finger."
"But during the functional verification phase, we ran into a big trouble, which was suppressing the immune response in the host patient."
"We first transplant the artificial organ to the patient's arm to see if it can get a good blood supply, and at the same time verify the congestion function of the corpus cavernosum. If everything goes well, it can be separated from the arm in about a few weeks. Come out and do subsequent transplants.”
"Unfortunately, the experiment failed at this stage. The patient's immune system destroyed the artificial organ. At the same time, we also failed to verify the hyperemia function. After the corpus cavernosum received blood supply, it did not expand automatically, let alone increase to the size we expected. .”
"After the experiment failed, we realized that we still have a long way to go. Human organs are far more complex than those of animals. Even if you make a structure that is exactly the same as a real organ, it is difficult to guarantee its functionality."
A trace of regret flashed in Ding Mian's eyes, and he sighed and said: "I later left this experiment and went to work on other things. I don't know what happened to my senior brother or whether he is still continuing. In the past few years, there has been no clinical success. news, maybe he also gave up research in this area."
"It's really scary. We are very close to success. We are just a few small steps away. If it is really done at that time, it will be a sensation in the world. Maybe I will join his laboratory and be forced to stay." It’s over there.”
Ding Mian was obviously a little scared when he thought of this, he patted his chest and said.
"What a risk. In this experiment, I got a little carried away and forgot to hide my strength. I almost couldn't control the ancient power in my body. I exposed my true talent and attracted the attention of the mysterious organization of Eagle Country."
"As soon as the experiment ended, another team immediately invited me to join their project. Damn, I came to the door so quickly. There must be a conspiracy. They must tie this genius like me to a chariot and stay in the Eagle Country completely. I will never be able to return to my country in this life.”
"I was so shocked that I broke out in a cold sweat. I was so careless and forgot to hide my clumsiness, so I made an excuse and flatly rejected their invitation."
"Hey, the success of the animal experiment is all due to my carelessness. Fortunately, when I was doing human organs, I realized this and didn't do much. Although it was a little exposed, it was not completely exposed."
"Later, the experiment failed, and Eagle Country turned its attention away from me. I was able to successfully graduate and return to China without being accused of stealing confidential technology and being detained in prison for the rest of my life."
Hearing this, Xue Shen couldn't help but look at Wen Renlong and conveyed a vague look: "Has he always been like this?"
Wen Renlong shook his head and made a gesture calmly: "It doesn't happen often. I only get sick when this topic comes up."
Xue Shen nodded heavily, then felt relieved and quietly gave a thumbs up to Wen Renlong.
The two communicated tacitly, and Ding Mian finally completed his introspection.
He looked at Wen Renlong with a look of compassion on his face and sighed.
"Brother Long, just because I want to protect myself wisely, this technology has not been available for a long time. Over the years, although I have never regretted it, I always feel that I can't help those patients."
"Think about men who have lost their confidence due to reproductive defects, traumatic injuries or previous cancer surgeries, as well as transgender men who have hope that this technology could completely change their lives."
"Because of my selfishness, I made them suffer for a few more years. Fortunately, I have you, Brother Long." He looked at Wen Renlong affectionately: "I fought hard and won this new project from President Wei. I On behalf of these patients, I want to say thank you."
Wen Renlong got goosebumps when he saw him like this. His butt slid on the sofa and he immediately backed away a meter away.
"Don't look at me like that, it's creepy. Come on, stop giving your speech and focus on the project."
"According to what you said, didn't the previous experiment fail? The most you can do is conduct an animal experiment, and it seems that the success rate is not very high."
Ding Mian didn't take it seriously, and said with a chuckle: "It will be very difficult to make a complete human organ. I'm not sure yet, but you are not, no, your friend is going to have enlargement surgery, isn't he? Then This is much simpler.”
"Oh, tell me in detail." Wen Renlong looked at him with burning eyes, his face full of dissatisfaction with the desire for knowledge.
"There are currently three ways in the medical community to change the size. One is to lengthen through ligamentoplasty, one is to implant a prosthesis, and the other is to fill it with the body's own fat."
Ding Mian calmly picked up the coffee, took a sip, and immediately frowned: "The coffee is cold, it tastes really bad."
Wen Renlong snapped his fingers at the speed of light: "Waiter, another cup of hot Americano."
Ding Mian put down the cup and explained in detail: "Ligament lengthening surgery requires very high qualifications of the hospital. If the technique is not superb, it will cause damage. Needless to say, implanting a prosthesis is common. Fat is extracted from the patient's abdomen and put into it. If injected into the organ, it can probably be extended by two or three centimeters, which is better than nothing."
Wen Renlong shook his head quickly: "Oh, you kids don't understand what is better than nothing. It is already very good to be able to extend it by two or three centimeters. It is of great use."
He looked at the two people turning their gazes and couldn't help but blush: "I'll just say it casually. Continue!"
Ding Mian coughed lightly and said: "Maybe I didn't make it clear enough. In fact, the length and circumference are increased by two or three centimeters respectively. However, this method also has shortcomings, that is, some fat cells will be broken down over time. But it’s not a big deal because the surgery can be repeated and it just costs some money.”
"Just like breast augmentation surgery for women, there is actually a huge demand for men's breast augmentation surgery."
"In short, if your friend wants to do this surgery, he can find a qualified doctor in China to do it. It is a normal plastic surgery. There is no need to be a clinical guinea pig. After all, there are still relatively high risks here."
Wen Renlong nodded thoughtfully: "Okay, I will advise him to try his best to do a Londin surgery first."
"However, if it is really small or the function is damaged, the operation will not make much sense."
"Yes, then we can only pray that our project will succeed as soon as possible."
Ding Mian reached for the coffee handed by the waiter, took a sip, and added with a trace of satisfaction on his face.
"Back to artificial organs, this is indeed a potential scientific research project. Artificial blood vessels, artificial bladders, artificial tracheas, artificial urethras, etc. are actually similar in structure. As long as one is done, the others will not matter much. Great technical difficulty."
"It's really difficult to create an artificial penis because it has certain functionality, and its reproductive function is also very important."
"Fortunately, it is only a part of the reproductive system. It is much less difficult than artificial uterus and main functional parts such as artificial testicles."
"Understood, understood!" Wen Renlong picked up the coffee and touched the cup: "Then I wish you immediate success and rescue the suffering brothers as soon as possible."
The three chatted for a while, then returned to the laboratory one after another to continue their work.
As soon as Xue Shen returned to the office, he learned good news.
"Great, the clinical trial application for artificial blood vessels has been approved."
"The fast track for innovation results is not bad. As long as the clinical trial results come out, the success of the project is certain."
He rubbed his hands together excitedly: "It's really exciting to think about it."
As soon as these words came out, he stopped and looked at his hands in astonishment, feeling at a loss of whether to laugh or cry.
"Gan, this action of rubbing hands is really like a big green-headed fly. It is also very obscene. How could I be infected by such an obscene gesture from him? It's really fatal."
****
"When I walk into Kunming First People's Hospital, why can I always see confidence on the faces of doctors and nurses?"
"Why do they always have unwavering faith when facing difficult, difficult and critically ill patients?"
“Why are technologies that fill domestic gaps successfully completed here?”
"Next, let's go into the cardiac surgery operating room at two in the morning and find out the answer to the question."
A female reporter appeared in front of the camera, introduced the program with a smile, and then walked into the brightly lit cardiac surgery room surrounded by photographers.
This is a special report by Kunming TV Station on the First People's Hospital. In order to highlight the hard work and dedication of medical staff, the special time in the early morning was specially chosen to film the program.
Generally speaking, most surgeries in hospitals are scheduled to be performed during the day.
Unless they are critically ill patients who are transferred to another hospital and need emergency surgery, it is usually late in the afternoon when they arrive. After preoperative examination and preparation, most of the time the surgery starts in the evening.
If it was delivered later, he would have to have surgery in the early morning and overnight.
When the female reporter came to the cardiac surgery department, she was mainly attracted by the brightly lit operating room.
There are no major surgeries in other departments tonight, only the cardiac surgery room has been lit for 24 hours.
"Wow, the surgery you were doing at 2 a.m. must be a very important major surgery."
The female reporter turned the camera to the lounge and whispered: "Lying on the sofa is Dr. Yunfeng from the great vascular medical team. He is taking a nap with his eyes closed. It is said that he will have surgery later, so we should take advantage of this gap. Take a break and gather your mental strength.”
"I heard from the nurse that his team had been in the hospital for a whole day and rescued five patients with type A aortic dissection on the operating table. This spirit of selfless dedication is really touching."
"The cardiac surgery team, from the director to everyone, has always demonstrated their mission of dedication to the cause of medicine and the treatment of patients."
"They are just like Dr. Yunfeng. Seven days a week, there are always days when surgery is required until two or three in the morning."
"Okay, after seeing their dedicated work attitude, let's take a look at their professional skills."
The camera changed and the female reporter walked out of the lounge and came to the bright white corridor.
Suddenly, her voice rose a little higher, her breathing became rapid, and she couldn't hide her excitement.
"Viewers, you must be curious, in such a busy department, where is the director?"
"In fact, we have just received news that Director Li from the Cardiac Surgery Department is leading a professional team to perform a thrilling major surgery."
"This operation uses technology that can be called the 'top of the cardiac and macrovascular surgery pyramid' and will complete a one-time replacement of the entire human aorta for a female patient."
"The patient was found to have an aortic tear, which also affected the main blood vessels nearby. The aorta in the chest, abdomen, and thighs were not only torn by dissection, but also stretched, like a balloon that could burst at any time. Life is in danger.”
"The only way is to replace the aorta throughout the body and replace it with an artificial blood vessel."
"Aortic replacement surgery is a major cardiac surgery operation and is very difficult. However, the hospital has performed it many times and it has been very successful."
"However, what is different from ordinary aortic replacement surgery is that this time the patient needs to replace systemic arteries, including renal arteries, lower limb arteries, almost a major blood transfusion from the heart to the thighs."
"In the words of doctors, this is definitely the ceiling for cardiac surgery."
"You know, replacing the entire aorta at one time is equivalent to building a new channel throughout the body."
"From the heart to the thigh, all blood vessels with a total length of nearly 1 meter must be replaced with artificial blood vessels."
"This is definitely the most difficult and technically demanding heart surgery in history. It is simply a miracle."
"There is even more amazing news, that is, the artificial blood vessels replaced by the patients are all from Sanqing Group. It is the first and only self-developed high-end artificial blood vessel in my country, and it is also the first clinical application. .”
The female reporter became more and more excited as she talked, with curiosity and shock written all over her face.
"Next, let's go into the cardiac surgery operating room and watch this pinnacle operation that makes history."
(End of chapter)
