Although I often hear about drug trials, this is the first time for Li Qing to participate in a clinical trial.
He picked up the "Informed Consent Form" and read it carefully as a habit.
The above content is very detailed, including the purpose of this clinical study, drug information, selection requirements, project procedures, precautions and research compensation, etc., and is explained very clearly.
"Clinical study of new drugs for antioxidant enzyme promoters... Candidates must have been exposed to ionizing radiation in a short period of time..."
"The blood volume collected in the entire trial is about 180 ml for men... The time of admission, taking medicine and leaving the hospital are respectively... dietary, tobacco and alcohol taboos..."
"Food and accommodation in the hospital for 6 days will be provided, and a compensation of 5,000 yuan will be provided."
Li Qing was immediately happy when he saw this.
"Hey, it's a good way to make extra money by taking a vacation. No wonder there are so many professional drug testers."
"It's not bad. If you get money, it's much better than a lab rat."
The doctor next to him also saw this and came over happily: "Lao Li, it's not bad. The bonus is higher than that of our department."
Another doctor was a little worried: "Isn't it true that the greater the risk of a drug, the higher the compensation for trial medicine? It's 5,000 yuan for 6 days. Is this money so easy to get? I feel a little scared."
Li Qing pondered for a moment, then shook his head and said, "There shouldn't be any problem. Sanqing's medicine has always had less side effects. Logically speaking, the risk is not great, and the price is high. It should be because it is a new medicine and there are no similar medicines, so the compensation for trial medicine is not high." As low as generic drugs."
"Haha, you're here, why are you worried? There's no risk in trying medicine, right? Don't think too much, just sign for the physical examination."
He was an optimist. He turned to the last page without even looking, signed the consent form, and went straight to the medical examination room.
The routine physical examination ended soon, and all the people in the interventional department met the recruitment conditions and were successfully selected.
After breakfast, everyone lined up and waited for check-in.
The pre-check-in inspection is very strict. Everyone has to take off their clothes and check their whole bodies. Even their shoes have to be taken off to check whether there is anything inside.
As for personal items such as cigarettes, lighters, and water bottles, they are kept in the clinical building and can only be returned when you leave.
After putting on gray pajamas and arriving on the second floor, Li Qing went directly to bed, feeling relaxed and comfortable.
He had not taken a vacation for more than a year, and this feeling of leisure was strange and comfortable to him.
"I can finally stay away from those endless surgeries for a while."
Li Qing enjoyed most of the time here. The air-conditioning temperature was neither too hot nor too cold, and each meal consisted of three meat and two vegetarian dishes. He could spend as much time as he wanted when he was not collecting blood.
Whether it's watching a drama, playing games, or even gathering people to play cards in public areas, no one cares.
Some colleagues used their own laptops to watch movies, and directly used up all the inventory accumulated in the hard drive over the years.
Some are obsessed with improving scores in the fifth row, and it is said that they have ranked first in the community.
Li Qing did not participate in any of these activities. His schedule was very regular. He watched the news and played short videos in the morning, played Landlords with a few poker friends in the afternoon, watched the news and TV series in the evening, talked to his family for half an hour before going to bed, and then hit the clock at ten o'clock. sleep.
Except that there is an indwelling needle in the arm and blood needs to be collected three times a day, which makes people feel a little uncomfortable, it is no different from being on vacation at home.
From the next day, his energy recovered a lot and he was not as tired as before he checked in.
Because his life was so healthy, he didn't know who to attribute it to for a while.
Is it because of good sleep or the effectiveness of the medicine?
Li Qing thought for a while and felt that the medicine he had just taken for a day should not have such an immediate effect. It seemed that it was because he slept well and was not stressed.
But on the third day, when he looked in the mirror and brushed his teeth, he found that the redness and blisters on his forehead and chin had disappeared.
"No way, a regular schedule is only so effective." Li Qing couldn't help but mutter to himself.
After collecting blood, he couldn't help but ask the staff.
"Well, I want to ask how the SOD level is? Have the white blood cells increased?"
The staff member didn't even raise his head and said casually: "Where are we now? It's only the third day. It's not so obvious. Besides, so what if I know, you can't understand."
Li Qing still wanted to try harder: "Well, actually, I am also a doctor in this hospital, so I can understand it."
The staff member raised his head and glanced at him, seeming to remember something, with a look of embarrassment on his face: "This is a double-blind trial, I can't say anything about the relevant information casually."
Li Qing persisted and said, "That's right. I've been feeling particularly good these past two days, so I'm a little curious. Just tell me the white blood cell count. I'll naturally know what's going on."
The staff member nodded: "Okay, let me see, is it Li Qing?"
After operating the computer with both hands, Li Qing's daily test results soon appeared on the screen.
"Well, the SOD value is 145 and the white blood cells are 4280. Although it is not high, it is within the normal range."
"Wait a minute, let me take a look at the values when you checked in so that we can compare."
"What? Your SOD was less than 100 before, but your white blood cells were 2,800?"
The staff suddenly exclaimed and stared at the screen with an expression of disbelief.
After a while, he stammered: "Your value rose so fast. It returned from a low value to normal in two days. No wonder you feel in good condition."
"I can't wait to see the results of your blood test today."
Li Qing was also surprised, but he was more delighted. Anyone who could regain health in a short period of time would be overjoyed.
The staff member had regained his composure at this time, adjusted his glasses, and explained: "The main reason is that your foundation is poor, so the improvement is obvious. If you are a normal person, the change may not be so big."
Li Qing couldn't help but smile bitterly: "My radiation dose pen exploded at 120 sieverts, and I almost died. Is my condition not bad?"
The staff looked sympathetic: "That's true. You are in the interventional department, right? It's really not easy."
Li Qing recalled that value and felt a little scared, but after thinking about it, he asked again.
"I know that radiation sickness depends on internal or external radiation. Mine is caused by small doses of external radiation. As long as I no longer receive radiation, it will slowly heal little by little."
"But returning to normal values within three days is too exaggerated. Is it the result of taking drugs?"
"Look at it this way, I should be in the experimental group, not the control group?"
Having said this, he suddenly became very happy and started to praise:
"The new drug Sanqing is really effective and it works so quickly. It's amazing."
"Shhhh~" The staff member was shocked for a moment and almost covered his mouth: "My Director Li, what we are saying is that this is a double-blind trial. Don't make it public. Do you know that?"
Li Qing showed an "I understand" smile and nodded repeatedly: "Don't worry, I will definitely keep my mouth shut. I won't say anything until I'm discharged from the hospital."
Walking all the way back to the ward, his steps were extremely brisk and he couldn't help humming a song.
Colleagues marveled at his condition: "Old Li, are you showing your second youth as a middle-aged man?"
"Your face is shining brightly. What's going on? Did you find someone outside behind your sister-in-law's back?"
"Where are you thinking?" Li Qing's eyes widened, and he immediately showed the dignity of the deputy chief: "Just test the medicine carefully, don't think about it here and there."
However, some people immediately guessed: "Lao Li, your condition is indeed a bit too good. Are you lucky enough to be in the experimental group? Those of us who don't feel it are just taking a placebo."
Li Qing glared angrily and said: "Okay, okay, you guys are eating and drinking well here. If you sleep enough for 8 hours a day, even if you take a placebo, your health should be better."
But then, he changed the subject and admitted directly: "If you don't tell me, I know that I must have taken medicine to get better so quickly."
"I'm just telling you, don't spread the word. This is a double-blind trial."
Everyone nodded in unison, just like a row of chickens pecking at the rice at the same time, with uniform movements.
A smug smile appeared on Li Qing's face, he was both satisfied and contented as he spoke slowly.
"You all know that before I came in, my radiation dose was the highest, it was 120, and my white blood cells dropped below 4,000. And I am the oldest, so I am really weak."
"However, now that I have rested for three days, I feel that I have almost recovered. I think this must have something to do with sleep, but it is not major."
"So, I ran to the staff and revealed my identity as the deputy director of the interventional department, and then I got the results of my blood tests in the past few days."
"It turns out that my SOD and white blood cell values have risen to the normal range."
"Although it's still a little low and just crossed the line, you know, it's fine now. To put it bluntly, even if our Director Yao falls down from exhaustion and passes out in the operating room, I can go over immediately, brush my hands, and replace him. He went on stage to do surgery.”
"Oh! The value has returned to normal?" Everyone gasped at the same time and looked at him in shock.
After a silence, it was like a hornet's nest exploding, and the crowd became excited.
"Director, this can't be possible. I remember that when you first came in, the radiation dose was so high that the staff didn't dare to stay around you for fear of being radiated by you."
"Even if you rest for a few days and your body will slowly recover, it won't be so fast."
"Is this the scary thing about the experimental group? Damn it, I hate it so much. Why am I in the comfort group?"
"The effect is so obvious, even a blind person can see it. Why do we need to be double-blind? We can just let us all take the medicine together."
"No, I have to go find the staff to make sure. I think I'm in good condition these days. I can't be taking a placebo."
"I also want to know my test results, otherwise I will feel like there are ants crawling around in my heart, and I will always feel itchy and uncomfortable."
"Let's go together."
I don't know who shouted, and everyone immediately ran away, leaving Li Qing alone in the entire ward.
He opened his mouth, wanting to say something, but nothing came out.
All I know is that I feel good for a while, but when I take the blood collection in the afternoon, I will probably have a headache.
The experiments that followed were no longer secret.
Because the performance of the subjects who took the medicine was so obvious, their physical fitness has been greatly improved, and they are extremely healthy.
The medical staff in these interventional departments are very tired from working overtime all year round. They are all in a sub-healthy state and have more or less minor ailments.
Due to long-term exposure to rays, skin is prone to allergies and hair loss is easy. No matter how thick my hair was when I was young, hair would fall out all over the place when I took a shower at night. Now my hair has fallen out less.
In addition, due to long-term weight bearing and standing, they also have problems such as varicose veins and intervertebral disc herniation.
These are the injuries caused to the body over many years. Even if you take a break for a week or two, it is difficult to fully recover.
But now, these little problems are gradually disappearing.
Whether it is the test results or the doctors' own feelings, they all feel that they are refreshed, their waists are no longer sore, their backs are no longer painful, their faces are no longer prone to acne, new hair has grown on their foreheads, and their skin has become smooth. Much better, not as rough as before.
Although the trial subjects who did not take the medicine but only took the placebo rested well and regained their energy, they still had a lot of backaches from lying down or sitting every day.
In this way, the contrast between the two is too sharp, and the experimental group and the control group completely lose their meaning.
The Sanqing clinical research team is also very happy.
The previous clinical phases were all done on healthy people. They also selected young college students, all of whom were vigorous and vigorous. Except for the difference in SOD detection data, it was really impossible to see that the drug had any special effect.
Although there are some patients in the second clinical phase, there are more elderly people, and the rise and fall of SOD values are also measured. Even if the elderly are healthy, their performance will be limited.
Who would have thought that if it were these traumatized middle-aged people, the effect would be so good.
It's like taking a shot of chicken blood, all kinds of physical data are rising steadily, and the contrast is full.
Now, statistics is much easier, and the experimental results become particularly beautiful.
The days passed quickly, and after a few days, the subjects left the clinical building one after another.
They will return to the interventional department and do some daily work. As long as they do not enter the operating room, the possibility of being exposed to radiation in the department is still relatively small and will not have much impact on the body.
One week later, the second cycle of drug testing will continue.
In this way, after the two cycles of drug trials are over and the patient has completely recovered, he can come back and continue the surgery to replace Director Yao, a hard-working old scalper.
During the middle week, Director Yao had already heard about the miraculous effects of antioxidant drugs, and his mouth watered with envy.
After he was replaced, he didn't even return home and went straight from the operating room to the clinical building.
However, the number of people was much smaller this time. The registration staff already had experience and directly handed over an information letter.
Director Yao didn't even look at it. He just signed and went for a physical examination.
After the physical examination, I found some familiar faces.
"Director Yao, are you there?" A strong, bald man strode towards him.
Director Yao took a closer look, suddenly smiled, stretched out his hand from a distance, and greeted him.
"Hey, isn't this Director Fang from the Interventional Department of the City Hospital of Traditional Chinese Medicine? Why, are these people from your department?"
"That's right, the results of your department's drug trials are so good that word has spread all over the place." Lao Fang laughed boldly: "I quickly brought these bastards in the department over."
"I estimate that in a few days, brothers from other city hospitals' interventional departments will also come, and there may also be some radiation sickness patients from the province who will have to come. By then, there will be even more people."
Director Yao rubbed his hands together excitedly: "Oh, the more you talk about it, the more I look forward to it."
Lao Fang suddenly lowered his voice, pointed to his bright forehead, and said mysteriously: "Old Yao, to be honest, my hair has been bald for several years and has never grown back. This time it's just for this reason. Come."
"Haha, me too." Director Yao raised his eyebrows and nodded in sympathy.
The two looked at each other and smiled, saying nothing.
(End of chapter)
