"The patients are all awake," the nurse said in surprise.
As the third injection of nano pills entered the bodies of the two patients, it didn't take long for them to wake up one by one and regain consciousness.
The patient in bed No. 1 started coughing violently as soon as he opened his eyes, and spit out a large mouthful of white phlegm for a while.
The nurse was overjoyed when she saw it: "Director, the patient's sputum has become clearer and the airway has become unobstructed, which shows that the treatment effect is very good and the lung infection has been reduced a lot."
Director Cui stood aside, nodded, and a smile appeared on his face.
"The patient's condition is gradually improving, which is not easy."
At this time, the attending doctor hurried in with a stack of imaging data.
As soon as he saw Director Cui, he beamed with joy and said, "Director, these are lung CT scans of two patients. They are no longer white lungs."
Director Cui took a look at the CT image and saw that the lungs on it were no longer white, but returned to normal black, in sharp contrast to the surrounding white edges.
He couldn't help but admire loudly.
"It's amazing. In just three days, the CT lungs no longer appear white."
"The relevant inflammatory index has also been reduced a lot, and other organs such as the heart have no signs of infection or damage."
He pondered for a moment and told the attending doctor: "The main thing now is to design a follow-up ventilator weaning plan and a rehabilitation plan."
"The patient is still relatively weak due to bed rest for more than 20 days. After eating for a few days, nutrition and energy are replenished, and the strength is restored to a certain level, he should be able to wean himself off the ventilator and breathe normally."
"Okay, I will design a plan later and show it to you." The attending doctor nodded in agreement, then smiled at Xue Kun beside him and said.
"Although the sputum turns white and the symptoms are relieved, it does not mean that the patient is completely cured. I am afraid that I will have to continue to inject nano-pills and take antibiotics for a sufficient amount and for a full course of treatment to achieve the best therapeutic effect and avoid a rebound of the disease."
Xue Kun smiled slightly: "Yes, it must be used in sufficient amount according to the course of treatment. Antibiotics are all like this, I understand."
The use of antibiotics is all about treating the disease less and not more. Once used, it must be used in sufficient amount to completely eliminate the germs. Otherwise, if you stop using it halfway, it will easily lead to drug resistance.
Director Cui looked at Xue Kun with a smile and gave a thumbs up: "Xiao Xue, Sanqing's nano pills have done a great job this time and cured the last two patients infected with MRSA."
"This super bacteria, which is a headache in any hospital, was easily eradicated like this. Thank you so much."
"The biggest headache for hospitals is nosocomial infections caused by various super bacteria. Nanopills are a big killer for us."
At this point, he seemed to think of something and slapped his forehead: "Such an awesome clinical trial result, I have to publish a paper. Those old men with high eyes in the tertiary hospitals in Haishi and Beijing will see it. I’m not jealous to death.”
He casually stuffed the case information into the arms of the attending doctor and urged: "What are you still doing? Hurry up and write a paper. Once you write it, you should have a core article this year."
The attending doctor was instantly overjoyed: "Okay, director, I'll go right away."
Director Cui carefully checked the patient's condition and found that his physical condition was very stable, so he took Xue Kun out of the ICU.
As soon as he went out, he patted Xue Kun on the shoulder and said with a fearful expression: "This nosocomial infection is a big deal. If there were no nano-pills, if the patient had any shortcomings, it would be a major medical accident, and the consequences would be simply disastrous. Imagine.”
"This time I really thank you."
Director Cui's thank you seemed particularly sincere even when no one was around.
Xue Shen was about to say something when suddenly, a tall, thin, middle-aged male doctor walked towards him.
He originally had a straight face, but after seeing Director Cui, his expression became more gloomy.
"Old Cui, I heard that the patient's lung infection is under control?"
As soon as Director Cui saw him, the smile on his face froze, and he immediately became serious. He nodded and said, "Yes, thanks to the nano pills provided by Sanqing, the patient's condition is gradually improving. It is estimated that he will be fine in two days." Breathe offline.”
The tall, thin male doctor said coldly: "Old Cui, you have to bear a lot of responsibility for this nosocomial infection. Fortunately, the patient was rescued, otherwise it would have been a major medical accident."
"The dean has given the Infectious Diseases Department of our hospital the full responsibility to handle this matter. I have already reported it to the health department and the Centers for Disease Control and Prevention."
"According to the results of the on-site epidemiological investigation, through sanitation testing, related specimen collection, etiological examination and other work, the cause has been found out. The main reason is the negligence of our ICU and non-standard hand hygiene, so management must be strengthened. .”
"I will come here every day to check the sanitation and disinfection situation. Everyone must wash their hands frequently and disinfection must be done properly. I hope you won't let me down."
Director Cui's face suddenly fell, but he knew that the other party was right. Since nosocomial infection occurred in the ICU, he was the one who took the blame and no one could take it away.
Seeing that he had a sad face, the other party continued: "Don't look like that. Although the patient was rescued, he also suffered a lot of extra suffering. I think the family members are angry in their hearts. Maybe they want to find someone." The hospital wants compensation.”
Director Cui couldn't help but was stunned: "No way, haven't all the patients been rescued and they are all well?"
The tall, thin male doctor sneered and said, "Isn't it a small amount of money to pay hundreds of thousands of dollars because of hospital sickness?"
"Luckily you were rescued. What if you weren't?"
"A few years ago, five infants and young children died in Shunde Hospital due to a pediatric hospital infection. The hospital's top three hospital brand was removed, and the president and a bunch of directors were dismissed. You don't know this, right?"
"This..." Director Cui was speechless. The matter of hospital feeling is either a big deal or a small matter.
If it is big enough, it can knock down all the senior officials of the hospital, and even take off the top three A brand.
Even if it is small, it can be calm and make no waves. It can even be treated as if it never happened at all.
As for how to evaluate the size, it naturally depends on whether the patient has been injured or not.
Thinking of this, he felt a little more grateful to Sanqing.
If two patients died due to this hospital infection, then he would definitely not be able to continue being the director of the ICU, and his career prospects would be ruined.
Director Cui mused: "The patient in bed No. 1 has had chronic obstructive pulmonary disease for many years and has been taking antibiotics all year round. He has never had any invasive surgery since he came to our hospital. So the blame can only be on the patient's poor immunity, which has nothing to do with the hospital."
"Only the patient in bed 2 is in trouble because he has just had a craniotomy for cerebral hemorrhage, which is a bit troublesome."
The tall, thin male doctor frowned and said, "Then this is a hidden danger. Who is responsible for this patient?"
Hearing this, the expression on Director Cui's face suddenly became a little strange: "You don't want to hold someone accountable, do you?"
"Why not? I just had an invasive surgery and got MRSA in the general ward. There must be something wrong with this, and the relevant doctors must take responsibility."
Director Cui put his hand on his forehead and said speechlessly: "Then you might as well ask me, Old Cui, to hold you accountable. This is Dr. Jian's patient. She went to heaven after the operation. She had just come off the space station when the patient was admitted to the ICU."
The tall, thin male doctor's face became serious: "Is he her patient? It seems that the doctor in charge of the bed didn't take good care of her."
Director Cui said angrily: "Come on, the situation in the inpatient department is like that. The staff is complicated and family members are wandering around. If you have nothing to do, you might as well go there and clean your hands."
"Haha, after all, your ICU disinfection was not done properly. You'd better pray that the family members don't sue."
The tall, thin male doctor snorted coldly, passed Director Cui, and walked slowly towards the ICU ward.
"What bad luck!" Director Cui was suddenly in a bad mood and couldn't help but utter a curse word.
Xue Kun watched the whole process from the side. He rarely saw people from the hospital's infectious disease department. He was very curious about this mysterious department and couldn't help but ask: "Is this the legendary hospital's infectious disease department?"
"Who else could it be? It's the Department of Infectious Diseases in the hospital that controls the weather."
Director Cui was angry, and his wrinkled face was squeezed into a ball, like a broken flower that had been blown by the rain and wind all night.
He stumbled and sighed: "This is terrible. If the patient sues for compensation, I, Lao Cui, will probably be raped."
"Xiao Xue, I'm leaving first. You can go about your business. If you need anything, come see me."
He didn't want to talk anymore, so he waved his hand and left in a hurry.
Xue Kun shook his head. He was just a scientific research tool man. These disputes between hospitals and patients had nothing to do with him.
However, depending on the patient's condition, it is estimated that the infection will be completely cured with just two more injections of nano-pills.
This human clinical trial was very successful. He recorded all the details of the treatment. It seems that the clinical trial can be continued.
Nanopills have powerful therapeutic capabilities against superbugs, which is undoubtedly a good thing for major hospitals.
You know, superbugs only exist in major hospitals in most cases.
Because there are so many patients in the hospital and various antibiotics are widely used, the bacteria here have strong multi-drug resistance and are difficult to cure with ordinary antibiotics.
Nosocomial infection accidents in hospitals occur in endlessly every year, and it has become a common public problem.
The hospital has set up a special infectious disease department to manage this matter, which shows how serious the situation is.
But most of the time, superbugs are contained by advanced antibiotics, and no major medical accidents result in patient death.
Moreover, infected patients generally use a lot of antibiotics and develop drug resistance in their bodies. As long as they have not had any surgery, they can only blame themselves for being in poor health and not blame the hospital.
Only if a patient is infected by bacteria after surgery and multiple people die at one time can it be considered a major medical accident. This is also very rare in the industry.
Every discovery is news-worthy.
A few days later, the ICU patients continued to improve, were weaned off the ventilator, and were quickly transferred to the general ward.
At this point, the first human clinical trial of nanopills has come to a successful conclusion.
After waiving treatment costs for the patient, the family members did not pursue anything further.
Director Cui's career was finally saved.
In fact, the patient's family members come to the hospital for health reasons. If the patient had not had a serious problem, the family members would not sue the hospital.
Therefore, hospital infection is a lose-lose situation. Neither the patient nor the hospital wants to see such a thing happen.
Even if it happens, it is best to treat it as soon as possible, calm it down quickly, and control the damage to a smaller range.
The medical circle is small, and news spreads extremely fast. The fact that nanopills showed their talents in Kunming Hospital quickly spread to other tertiary hospitals, causing a sensation.
Nanopills can treat patient infections at a dose of one thousandth and reduce antibiotic resistance caused by overuse of antibiotics, which is undoubtedly very attractive to hospitals.
Any hospital that has patients infected with superbugs is willing to try the novelty of nanopills.
This undoubtedly accelerated the progress of clinical trials.
In addition, there are some special patients in the hospital who also see hope of cure.
These patients, for various reasons, are long-term users of broad-spectrum antibiotics, and their bodies have already developed resistance to most antibiotics.
Even if they try new antibiotics, because the dosage is large, they need to be used for a long time, and they have certain toxic side effects on the body, so after a period of time, the bacteria often develop resistance and come back again.
In fact, the development of drug resistance is inevitable.
Antibiotics are weapons used by bacteria to kill other bacteria.
Bacteria are living organisms and can easily mutate, making commonly used antibiotics ineffective.
For example, under long-term exposure, bacteria adapt to the efficacy of antibiotics, produce enzymes that inactivate drugs, or change the permeability of cell membranes, thereby preventing the entry of drugs, or even changing the original metabolic process, which will cause resistance. Medicinal properties.
The longer an antibiotic is used in society, the more times pathogenic bacteria come into contact with it, and the easier it is to develop resistance.
Moreover, drug resistance genes in bacteria can be passed between bacteria of the same species and different species through genetic materials such as plasmid DNA.
It can be said that as long as one type of bacteria develops a drug-resistant gene mutation, most bacteria will soon have this resistance.
Bacteria evolve in a very clever way. After using penicillin on a bacterial colony, most of the bacteria are killed, but occasionally a very small number of bacteria develop resistance mutations.
In this way, they were lucky enough to survive.
Then, the bacterial variant will pass on its resistance genes to its offspring. What's even more sinister is that it can easily pass its resistance genes to unrelated microorganisms.
During transmission, one microbe emits an attractant that attracts another.
When two bacteria come into contact, they open pores and exchange rings of DNA called cytoplasmic genes.
This process is called unsafe bacterial sex.
Through this mating, the cholera bacterium acquires resistance to tetracycline from the ancient common E. coli in the human gut.
This kind of spread is often carried out through the general environment and is difficult to prevent.
Especially now that antibiotics are being abused, rivers, soil, and animals are full of drug-resistant genes.
For bacteria, this has become part of the environment and is literally available everywhere.
For example, Staphylococcus aureus, which is widely found in nature, is originally a harmless microorganism for humans and animals and can be easily killed.
For humans with normal immunity, it can coexist peacefully with humans. If the resistance is reduced, it will cause some common infections, causing acne, food poisoning and diarrhea.
But when Staphylococcus aureus receives resistance genes from other bacteria, it will grow into a notorious superbug-MRSA, which is multi-resistant to many antibiotics and becomes a frequent cause of nosocomial infections.
Many patients were fine, but after only being admitted to the hospital and without any surgery, they were infected with superbugs and turned from a common cold into pneumonia.
It is very likely that the Staphylococcus aureus carried in the body transferred genes with other bacteria in the hospital, acquired drug resistance, and mutated into MRSA.
This is an arms war between bacteria, and humans have just cleverly used the arsenal of bacteria.
Only by taking adequate foot therapy and taking the medicine on time can the medicine in the body always be maintained at a reasonable concentration, and the possibility of drug resistance can be reduced by trying to kill pathogenic bacteria while minimizing side effects.
That's what it means to accomplish everything in one battle.
Nano-pills that can eliminate germs with only a small dose will undoubtedly play a powerful role in reducing the use of antibiotics and reducing widespread drug resistance.
Almost instantly, nanopills became famous and popular.
(End of chapter)
