"What kind of rare blood group alliance sent Sanqing a "Recommendation for the Development of RH-Negative Artificial Blood"?"
As soon as Wei Kang arrived at the office, he learned a piece of news that made him laugh or cry.
"The Rare Blood Group Alliance has branches in various provinces and cities with many members. There are more than 80,000 members across the country. They are very active in participating in various blood donation and charity activities, so they have a great influence on society."
The director of the administrative department respectfully handed over a document in his hand and said: "Supervisors from Haishi, Jiangsu Province, Zhejiang Province, Kunming City and other regions came together to submit proposals to Sanqing. This public opinion The power cannot be underestimated.”
Wei Kang took it, put it on the table casually, frowned and said: "They think well, but our artificial blood project is very tight in time, and I'm afraid it will be difficult to meet their needs."
"Of course, they are also willing to pay the price. If Sanqing is willing, tens of thousands of members of rare blood types across the country will voluntarily participate in clinical trials for free and provide all conveniences for research and development, such as extracting hematopoietic stem cells," the administrative director added.
"Well, since they are so sincere, they might consider it." When Wei Kang heard this, his heart suddenly moved and he quickly changed his words.
He thought of the thousands of volunteers needed for human blood clinical trials.
Generally speaking, when pharmaceutical companies conduct drug clinical trials, only terminally ill patients have the strongest willingness to participate, and they do not require any financial incentives.
For other diseases, more or less money is required to recruit drug testers.
Some impoverished people even regard drug testing as a job that allows them to make ends meet.
Projects such as artificial blood do not treat diseases in the first place, but are just to test the safety of the human body. Therefore, Sanqing had to pay each drug tester 5,000 yuan in order to recruit enough people.
In this way, the compliance of many experimenters is not very good. After receiving money for the first blood transfusion, they are not very active in subsequent reexaminations and often push back and forth.
As for asking them to cooperate with other inspections, it will be even more difficult.
Therefore, if it is replaced by volunteers with rare blood types who have a positive attitude and participate for free, it will naturally be easier to use than ordinary people.
Not only can tens of millions of dollars be saved, but there is no need to worry about patients refusing to come back after blood transfusions.
“In addition, this research and development proposal has also received the attention of the Provincial Blood Center.”
"Director Huang also called to express his support for the research and development of RH-negative blood and his willingness to provide all conveniences for clinical trials."
"That's it." Wei Kang was silent for a moment. It seems that this rare blood type alliance must meet to see what their specific needs are.
The next day, he met a group of people from the Rare Blood Type Alliance in the conference room, accompanied by Director Huang.
"Director Huang, nice to meet you!"
"Haha, I met Mr. Wei today. He is indeed young and promising, and his reputation is well-deserved!"
"Hello, Mr. Wei, I am Xie Tianyin, the director of the Haishi branch."
"I am Chang Hao from the Jiangsu Province Branch."
"I am Lin Xi from the Zhejiang Branch."
"Hello everyone, please take a seat."
The three parties exchanged greetings with each other for a moment and then sat down.
Wei Kang looked at the other side and couldn't help but asked curiously: "Can you tell me about donation? This way I can know more about RH-negative blood."
"Haha, that's what I meant." Xie Tianyin laughed. He looked at the other two people, exchanged glances with each other, and then spoke first.
"Actually, we all learned that we were born with panda blood by extremely accidental circumstances, and when we first found out about it, we were all in a state of 'bewilderment'."
"However, many of us are lucky because we learned about our situation before the danger occurred and found the organization in advance, but luck does not favor everyone."
"In fact, I have seen many tragedies in the more than ten years I have participated in rescue operations." Xie Tianyin said with some emotion: "In fact, panda blood is the same as that of normal people. The only dilemma is the lack of blood sources. As long as there is sufficient blood, There won’t be any tragedy.”
“Donating blood twice a year has become a habit that I have insisted on for twelve years. This blood flows in my body every day. It is ordinary, but for those who need it, it is worth a thousand dollars and is better than countless elixirs. "
Xie Tianyin recalled: "Years ago, I once saw a child who had just undergone chemotherapy for leukemia and was waiting for a blood transfusion. He was so weak that he had no strength to move his arms. But as long as the blood transfusion was completed, he would be able to be alive and kicking that night, just like ordinary people."
He smiled sheepishly: "I don't have much professional knowledge. At that moment, I felt particularly magical. I felt that blood is the most sacred thing in the human body. If I can devote myself to such a cause, I will die without regrets."
"There isn't much story behind it. The first time or two I was still very excited and felt that I was doing something special to save people. But as time went by, it became like eating and sleeping, and I really didn't feel anything at all."
The other two people immediately laughed heartily, nodded in agreement, and joined the discussion.
"In fact, the rescue over the years has been very successful. New people continue to join every year. They come from all walks of life, and many of them are volunteers who have received rescue and joined the team after recovery."
"We know very clearly that the abilities of individuals and even collectives are very limited. We will age and get sick. The only way to keep the blood source alive is to let young 'panda blood' join in."
"Love can be passed on, it can influence, and it can spread. When enough people have this awareness of blood donation, panda blood will no longer be in trouble."
"Human beings are animals that are born in trouble and die in happiness. It is the scarcity of panda blood that makes us awaken to mutual aid."
"Many of us are aware of the possible suffering in the future, and choose to organize, join forces, donate, and spontaneously form a mutual aid group, which solves part of the problem. This is the power of human wisdom."
Wei Kang couldn't help but nodded and said: "So now that you see artificial blood coming to your door, it is also based on this sense of worry."
"That's right." The three of them said in unison: "In fact, when I saw the news about artificial blood, I knew that the road of free donation would probably never go on again, because humans have found a better way. Method."
"I just said that new volunteers join every year, but there is also another point: old volunteers also leave every year."
"It's a good thing they haven't joined this circle. Once they join, they will inevitably encounter information about paid donations, and many people can't resist this temptation."
"'Panda blood' is both scarce and scarce. Because it is so precious, the price in the market is much more expensive than ordinary blood. It is beyond the imagination of ordinary people. It is difficult for ordinary people to refuse this temptation."
"After some volunteers have donated blood for a fee, it is difficult for them to accept unpaid blood donations, and they often choose to leave."
"Maybe you can't see it now, but as time goes by, there will be fewer and fewer donors. So we have to find new ways out."
Wei Kang asked: "How much does panda blood cost through illegal channels?"
Xie Tianyin smiled bitterly and said: "Generally, 400 ml of RH-negative blood costs about 20,000 yuan. If it is RH-AB, the rarest blood, 400 ml can be sold for 50,000 yuan. No one can ignore such a price and resist the temptation purely by relying on conscience. , because there will always be times when you need money.”
"You know, 200 ml of ordinary ABO blood type only costs a thousand yuan at most."
"It can be said that people with panda blood are walking ATM machines."
"When our members travel abroad, I tell them to be careful and never reveal that they have RH negative blood, otherwise they may be in danger."
Wei Kang frowned. This phenomenon of buying and selling blood as a resource made him feel deeply uncomfortable.
A surge of anger instantly surged into his heart: "They actually treat human blood as a resource. These traffickers have gone too far."
He has never had a strong desire to end this chaos like at this moment.
For humans, whether it is blood or organs, they should not be treated as a resource under any circumstances.
The sale of panda blood completely triggered his reverse scale.
At this moment, he had decided that even if artificial blood was to be mass-produced, rare blood types should be prioritized.
"Blood is being traded as a resource. This is unacceptable to me. I am willing to pay any price to eliminate this chaos."
Wei Kang said in a deep voice: "So no matter what the purpose of your coming, I will agree to it. This is not a difficult problem for Sanqing."
"In fact, if you are willing to provide hematopoietic stem cells directly, the manufacturing process will be simpler and faster than ordinary artificial blood."
"Before it is officially launched, Sanqing will provide a batch of fresh RH-negative blood every month at the market price of ordinary blood, which will be kept in the blood center for backup. What do you think?"
"In this case, plus your donation, we should be able to achieve double the protection effect."
"I hope that after artificial blood is officially launched, the underground blood black market can be completely eliminated."
Xie Tianyin and the others said happily: "Thank you very much. If there is no demand, there will naturally be no business. President Wei, your goal will be achieved as soon as possible."
"The three of us can each draw a tube of hematopoietic stem cells, and then we can leave." Lin Xi rolled up his sleeves, looking impatient.
Director Huang finally spoke up: "I would like to thank the General Health Minister on behalf of the blood center. As long as artificial blood is popularized and blood shortages no longer occur in blood banks, I can guarantee that illegal blood trading will disappear completely."
He represented the attitude from above, and his words were loud and convincing.
Wei Kang couldn't help but laugh: "Well, without further ado, it's better to choose a different day. You three go to the laboratory to draw blood first."
"Okay!" The three of them stood up one after another without asking any questions.
Seeing that things were going very smoothly, Director Huang immediately waved goodbye.
Xie Tianyin and the other three were left in the conference room, continuing to discuss with excitement.
Wei Kang called the stem cell laboratory and arranged for a blood draw, and then explained with a smile.
"You don't have to be afraid. Now to donate hematopoietic stem cells, you only need to draw blood. It is very convenient and does not have to be as painful as drawing bone marrow in the past."
"It is mainly carried out by extracting venous blood. First, granulocyte colony-stimulating factor is injected to concentrate the hematopoietic stem cells into the peripheral blood. Then, venipuncture is performed to extract the venous blood for processing and isolate the hematopoietic stem cells."
"Of course, the separation step will take a little longer, about 3-5 hours, but you don't have to worry. The whole process feels similar to blood donation, but it takes a little longer. Remember to take more rest and strengthen nutrition after you go back."
Xie Tianyin nodded and said, "It's okay. I'm already familiar with donating blood. Fortunately, the last time I donated blood was 6 months ago, so collecting hematopoietic stem cells this time will not have any impact."
Chang Hao hesitated for a moment and said, "The last time I donated blood was not more than 6 months ago. How about I contact my group friends and ask someone else to come over?"
Lin Xi also said worriedly: "Should we gather enough four people to get all four RH negatives, A, B, O, and AB, so that we are not afraid of missing any blood type?"
Wei Kang chuckled: "ABO blood type is not important. Our technology can remove this restriction, as long as it is RH negative. Sanqing's employees only have RH positive, so the previous artificial blood cannot produce RH negative." , if genetic modification is to be performed to remove the D antigen on red blood cells, unnecessary steps will be added and the success rate will be reduced."
"So it's best to use your hematopoietic stem cells, complete the predetermined genetic modifications, and then multiply them in vitro to produce artificial blood."
In fact, there are more than 30 antigen-related depressions on the red blood cell membrane, and hundreds of blood group-related antigens are inserted into them. It is impossible to remove them all. Only the antigens with the greatest impact, namely A and B, can be removed. and H antigen.
Even if the D antigen needs to be genetically modified and removed, it is not as convenient and quick as using RH-negative blood directly from the source.
"No problem." The three of them breathed a sigh of relief. If Rh-negative artificial blood could be used regardless of ABO blood type, it would definitely be a great event for them.
About ten minutes later, a young man wearing glasses hurried in.
"Ding Mian," Wei Kang waved, "This is the client I told you about. You just take him to the laboratory to extract some hematopoietic stem cells, and then do as I said."
"Mr. Wei, okay, I'll take them over right now. The granulocyte colony-stimulating factor is ready." Ding Mian walked over with a bright smile on his face.
"This is Ding Mian, he is in charge of the artificial blood project." Wei Kang introduced Ding Mian to the three visitors.
"Wow, so young and promising? He looks like he is in his early 20s." Xie Tianyin and others were stunned.
They never expected that the so-called head of the laboratory was actually a young man. According to their assumptions, he should be a kind-faced expert in his fifties.
Suddenly, I had a new understanding of the age of Sanqing Group from top to bottom.
"You three, please come with me." Ding Mian smiled and stretched out his hand in the direction of the door.
Soon, he brought Xie Tianyin and three others to the laboratory, extracted two tubes of hematopoietic stem cells according to the procedure, and put them in the refrigerator.
"Within three days, the genetic modification can be completed, and then it will proliferate in large quantities outside the body, which takes about a week, and finally it will be officially converted into blood, which will take another week."
"RH negative blood can be provided in up to 18 days." Ding Mian explained: "I will contact you at that time and provide the blood to the blood station."
The three of them were shocked again: "Is it so fast? No need for us to do anything else?"
"Nothing else is necessary, but the clinical trial for RH-negative blood requires more active participation of your members."
The three of them nodded repeatedly: "That's right. Thank you so much. Brother, you are so young. Do you have a girlfriend? There are many beauties in our group. I can introduce you to you. You are so young and handsome, you must be very popular with girls. welcome."
Ding Mian's face suddenly darkened: "I gave you blood, but you actually covet my body."
He quickly shook his head and said: "I am only 20 years old, still too young. As a man, I must first establish a career and then start a family. Besides, I am usually too busy with work and have no time to fall in love."
"Oh, that's right. It won't affect your work."
Upon hearing this, the three people stopped insisting and asked some questions related to artificial blood before leaving one after another.
Recently, I have been coughing every day, so much that the tubes in my lungs are about to come out, and then I have severe chest pain, and I still feel weak, so I am sorry for the lack of updates!
It is said that it takes two or three weeks for the cough to subside. I hope it will get better after New Year's Day.
(End of chapter)
