Chapter 360: The Power of Helicobacter Pylori

Style: Science Author: Riding a pig to dig a holeWords: 4344Update Time: 24/01/12 20:04:28
Wei Kang was surprised when he received a call from Sun Chengren.

"What? You went back to your hometown and had a drink, and the whole family was infected with Helicobacter pylori?"

"Have you been diagnosed with gastric ulcer? Let me go. I know that the bacterial infection rate is very high, but I didn't expect it to be so high."

"Okay, no problem. You and your family of three can apply on the Longtu APP and join the Phase III clinical trial. It should be no problem."

"Our Helicobacter pylori has a very good bactericidal effect. It is a narrow-spectrum antibiotic that only inhibits Helicobacter pylori. Unlike broad-spectrum antibiotics like amoxicillin, which can cause damage to intestinal flora and affect the digestive tract healthy."

Sun Chengren was very happy after hearing this: "That's great. I heard that quadruple medicine has strong side effects, so I don't want to take it. I haven't thought about intestinal flora yet. In this case, of course it is developed by us. The medicine helps."

Wei Kang reminded: "But if you participate in the trial, you will probably be assigned to the control group. You'd better be mentally prepared."

"It's okay, I understand. Besides, I think my luck isn't that bad, haha." Sun Chengren said nonchalantly.

He suddenly became a little curious and asked: "Xiao Kang, did you spend the Chinese New Year at Jian's house? How did it feel?"

Wei Kang hesitated instantly: "That's it. I had a New Year's Eve dinner and stayed for two days. I went back to the company on the second day of the new year. They were very polite, so I should be quite satisfied."

Sun Chengren chuckled: "Who can be dissatisfied with a son-in-law like you? Seeing that you are developing so smoothly, then I will be relieved."

"By the way, when you get engaged later, you have to go back to your hometown in Gan Province to recognize your relatives. Although your grandparents are gone, there are still some uncles and uncles here. You must notify us when the time comes."

Wei Kang was silent for a while and said calmly: "I know."

After hanging up the phone, he couldn't help but think of some past events.

My father's hometown is in Yushan County, Gan Province. He came out to work early. After saving up, he started a pharmaceutical company.

Because the Sanqing Mountain in my hometown is famous for its beautiful scenery, it was named after Sanqing. As for my mother, she was married outside. It is said that she has a bad relationship with her natal family and rarely goes back.

He grew up in Kuncheng since he was a child. His parents were busy with work and only went back to his hometown to visit relatives during the Chinese New Year. He rarely went back during the week, so he rarely interacted with relatives in his hometown. name.

Later, my grandparents passed away one after another, my parents also left, and all my immediate family members were gone.

Only my uncles and uncles on my father's side remain in contact with me occasionally, and they also joined the family WeChat group.

Whenever there is a festival, he will scatter red envelopes wildly in the group, but other than that, he doesn't have much else to do.

He still has a good impression of his father's relatives. Knowing that he is so rich, he didn't come to borrow money for the autumn breeze, which shows that he is a good character and worth dealing with.

As for the relatives on his mother's side, he has no contact with them for a long time. He has no impression of any relatives other than his grandparents.

I vaguely heard my mother say that her natal family seemed to favor boys over girls and treated her very poorly. Later, when she saw that she was getting married well, she always found various reasons to borrow money and was often shady. So after her grandparents left, they immediately severed the relationship.

Therefore, Wei Kang didn't even have any contact information for his relatives on his maternal side, and he also made up his mind that if he got married in the future, he would only invite relatives on his father's side.

In fact, based on his original intention, he didn't really want to go back to his hometown, mainly because he was too lazy to do it, but for such a big event as getting married, it couldn't be justified not to go back to his hometown.

According to traditional customs, when a new member of the family is born, he has to visit the graves of his grandparents to pay homage to his ancestors, to appease the spirits of his elders in heaven, and to take his wife to meet relatives, all of which he has to do in person.

"Hey, these trivial matters of family dealings are really troublesome. Fortunately, we just got married this time, otherwise it would be too annoying."

Wei Kang pinched his eyebrows and couldn't help but sigh.

He really missed the days when his parents were still alive and he never had to worry about these trivial matters.

But now that he is a proud figure in the Lao Wei family, these trivial matters of welcoming and sending him off will probably be inevitable in the future.

****

Sun Xiaoshi opened her address book and searched through it from beginning to end, and finally found Gao Yuan's WeChat ID among her new friends.

After the wedding banquet, the two of them hadn't chatted much, so she had no impression of this number.

"Now I remember you." Sun Xiaoshi thought bitterly and labeled him as the 'bad breath boy'.

She thought about it for a long time before sending a message.

"Hello, I am Sun Xiaoshi, who was sitting next to you at the wedding banquet. After we came back, our family went to the hospital for a check-up and found that we were infected with Helicobacter pylori. We may have gotten it from a dinner party in my hometown, so I wanted to kindly remind you to get tested as soon as possible. examine."

As soon as the message was sent, it was replied within seconds.

"What the hell?"

Immediately afterwards, messages came one after another, like a barrage of firecrackers.

"Did you infect it to me?"

"No wonder I've been feeling sick to my stomach since I came back. It turns out I got the infection from eating with you."

"Just wait, I'll go to the hospital for a checkup tomorrow. If something happens, I won't spare you."

"???" Sun Xiaoshi was stunned for a moment, and her liver ached from the anger of the other party's slap.

She took a deep breath, suppressed the anger in her heart, and replied: "Don't slander anyone. There's no telling who will infect who."

"I always remind you with good intentions. If you don't believe it, just pull it. I wish you good luck!"

After saying that, he threw away his phone and ran to complain angrily.

When Sun Chengren learned about this, he was also a little unhappy: "What did this man say? Forget it, we have already been notified anyway. Even if he really has a stomach bug, it is none of our business."

Soon, Sun Chengren applied for a clinical quota for pylorispirin and took his family to the hospital again.

It's just that this time he came to test the drug. After some examination, he was randomly assigned to the positive drug control group, and he will take the quadruple drug that has been on the market for comparison.

My daughter and wife were assigned to Sanqing’s drug team.

Sun Chengren couldn't help but smile bitterly. He thought he could escape the poison of Quadruple Drugs and directly use Sanqing's new drugs. He never expected that he would come back after going around in a circle. It was really bad luck.

"It's okay. When the control experiment is over, I will be given pylorispirin." He comforted himself, raised his head and swallowed the pill.

Not long after, he felt a headache. As soon as he lay down on the bed, he felt nauseous and had a metallic taste in his mouth.

"Damn, I'm so unlucky." Sun Chengren looked at his energetic wife and daughter, and couldn't help feeling depressed, and immediately closed his eyes in anger.

When eating, there was still a metallic taste in his mouth, and nothing he ate tasted good or tasted at all.

And because he took too much medicine, he was half full after eating it, causing him to have no appetite for food.

A few days passed, and Sun Chengren lost weight visibly. He couldn't eat or sleep every day, and he was very haggard.

Both his wife and Sun Xiaoshi realized something was wrong with him, and they were all extremely anxious.

"Dad, how did you become like this? Why are the adverse reactions so serious?" Sun Xiaoshi was not idle during this period. She probably learned some knowledge about clinical trials and knew that this was a manifestation of side effects.

Sun Chengren was lying on the bed, squinting his eyes, and said feebly: "Hey, just survive one cycle. It's all about treating diseases anyway. As long as it can be cured, it doesn't matter what kind of adverse reactions it is, the results are important. .”

The wife couldn't help complaining: "It seems that the medicine you took is not good. You see, the medicine Xiaoshi and I took didn't have any reaction. We just had a little acid reflux in the first two days, but then it was fine. I don't have any pain here either." I feel like nothing is wrong.”

"If I had known, I would have changed with you. Anyway, I am young and recover quickly. It doesn't matter if I feel uncomfortable. I can also lose weight. You are already old and you will definitely not be able to bear it."

Sun Xiaoshi couldn't help but shake her head when she saw her father's miserable state.

Sun Chengren sighed, pitifully and helplessly, and began to close his eyes to rest.

The experiment of a course of treatment ended quickly, and the doctor began to test the effects of the treatment on the three people.

After Sun Chengren took the C-13 test, he asked with a worried look on his face: "It should be fine. I feel that the effect of this medicine is quite strong, and it knocked me down directly."

The doctor looked at the test results and couldn't help but frowned: "Well, the metronidazole you took has developed resistance. Although the treatment has a certain effect, it has not been completely cured, and remedial treatment may be necessary."

"What?" Sun Chengren was stunned for a moment and couldn't believe his ears.

He suffered a week and lost ten pounds, but he got this result?

It's really unacceptable.

He couldn't help but trembled: "What kind of remedial treatment?"

The doctor didn't even raise his head, thinking as he replied: "You are already resistant to metronidazole. If you use rescue treatment, you have to increase the dose to overcome the resistance. However, the efficacy has improved and the adverse reaction rate has also increased." It will increase accordingly.”

"Either you can change to a non-resistant antibiotic, such as furazolidone, but the side effects of this drug are quite high. Considering your age, it may be more painful and may not be bearable."

Sun Chengren shivered instantly and almost cried.

"Doctor, can I not take this medicine? No, if I don't want it, just treat it. Can't you just give me the new medicine of Sanqing? I beg you, look at my old bones. I really can't stand the trouble anymore."

The doctor looked up at him, nodded and said, "Indeed, if you were a young man, I might still continue to give you remedial treatment, but you are like this. If you continue, it will be inhumane."

He waved his hand and said: "Okay, you can end the clinical trial. We will give you Sanqing antibiotics for treatment soon."

Sun Chengren was immediately overjoyed and thanked him repeatedly.

The test results of my wife and Sun Xiaoshi also came out. The new drug was very effective. After a week of treatment, the Helicobacter pylori in their bodies was completely eliminated.

The two breathed a sigh of relief and left happily.

Before leaving, Sun Xiaoshi comforted her father and said, "Dad, don't worry. You can see how effective I am. I only need to take it for a few days and everything will be fine. You must be the same. Mom and I are waiting for you to come back healthy." "

Sun Chengren also became energetic and full of expectations for the results of the next drug test.

Soon, he was taken aside by the nurse and took a white pill.

Although high-dose quadruple broad-spectrum antibiotics can kill Helicobacter pylori, they also cost the body a heavy price.

That is a complete reshuffling of the body's microbial environment. All flora, good and bad, are eliminated, which is equivalent to washing away the talent.

However, after the body is washed away, the bacteria are also washed away. There are always some drug-resistant bacteria that will be screened out and become survivors. If they are good drug-resistant bacteria, then congratulations, the patient will most likely be able to recover almost as well as before the treatment. Maybe It should be better.

If bad drug-resistant bacteria survive, or if Helicobacter pylori itself develops drug-resistant strains and survives, then the patient will most likely have to take antibiotics several more times. If a vicious cycle is formed, it means that the body is hit by GG.

Faced with such a bacteria that has coexisted with humans for many years and evolved to be so tenacious, the best treatment option is to use targeted narrow-spectrum antibiotics to avoid damage to other flora in the body and to avoid destroying the normal microbial balance of the human body.

Therefore, only Sanqing’s Helicobacter pylori is a truly symptomatic medicine.

After Sun Chengren took the medicine this time, he felt very good. Except for a little nausea and gastric acid reflux, there was no discomfort at all.

Compared with the previous adverse reactions, this is nothing at all, it is simply a piece of cake.

By lunch time, the unpleasant metallic taste in his mouth was no longer there, and his appetite was much better. In addition, he had been hungry for so long, and his mouth watered when he smelled the aroma of food. He ate a big bowl of rice and was very satisfied. Burping.

"That's great. As expected, when it comes to which company is better at developing new drugs, it still depends on Sanqing."

Sun Chengren thought smugly while picking his teeth.

If the damn germs hadn't multiplied in large numbers and made his stomach problems so serious, he would rather wait until the new medicine came on the market and buy it directly instead of taking those damn quadruple antibiotics.

He had always heard that patients would have various adverse reactions after taking medicines. He used to be a bit dismissive of this, thinking that patients were too pretentious. As long as the disease was cured, it would be good. What's the discomfort? Can it be compared with life?

Unexpectedly, I finally tasted the bitter pill now, and instantly understood what this painful side effect was all about.

Sure enough, you wouldn't know how uncomfortable it would be if this didn't happen to you.

As the saying goes, if you compare yourself with others, you will die, but if you compare goods, you will throw them away.

After taking Sanqing's medicine, he could no longer tolerate the adverse reactions of other medicines.

He immediately swore that when he got sick in the future, he would only take medicine from his own company.

If there is no such drug, the company will be forced to develop it as soon as possible.

Anyway, don't let him suffer anymore.

Next, after he took the medicine for five days, when he was checked again, he found that the Helicobacter pylori in his body had been completely eliminated.

Although the previous quadruple antibiotic treatment developed drug resistance and had a moderate effect, it also had a certain inhibitory effect.

Coupled with Sanqing's special antibiotics, a two-pronged approach, the originally serious bacterial infection was quickly cured.

The next step is to treat gastric ulcers.

After the main cause of the disease is removed, I believe that as long as you take medicine step by step, you will make a complete recovery soon.

Sun Chengren happily left the clinical building and turned into the outpatient building.

I found a doctor and prescribed some medicine to treat gastric ulcers, and immediately returned home.

He has fully realized the power of this new narrow-spectrum antibiotic.

It is foreseeable that when a new drug is launched, it will definitely set off a storm and cause a sensation.

(End of chapter)