Wei Kang also saw news about NASA on the Internet, but he didn't take it to heart. He just found it a bit ridiculous.
He suddenly had the feeling that his eyes were opened. It turned out that bureaucrats all over the world had similar faces when they cheated on funds.
It is not news that many institutions in Eagle Country purchase equipment from the East, directly change their appearance, put on the appearance and branding of compliance, and then use it blatantly.
Unexpectedly, NASA, which claims to be the temple of science and technology, has also fallen. It is no different from other agencies. It still engages in this kind of business of selling dogs over sheep's heads, and falsely promotes it as its own technology, which makes people laugh out loud.
Thinking of this, he couldn't help but shake his head in disappointment. Compared with the China Space Center, this kind of NASA is simply too far behind. It can't even seek truth from facts. How can it gallop in the ocean of science and technology, and how can it go towards the sea of stars? .
At this moment, the phone suddenly rang.
At first glance, it was Fang Heng from the space center.
Fang Heng came here to announce the good news: "Mr. Wei, good news. The portable universal monitor is very successful. The space center wants to reach a long-term strategic partnership with Sanqing. In the future, in the space medical field, whether it is drugs or equipment, we must Strengthen cooperation."
Weikang was very happy to hear this. This is indeed good news. In this way, any medical devices developed in the future can be directly displayed and promoted on the space station. At the same time, it will be more closely tied to the country's aerospace field. As far as the Three Purities are concerned, it is true that there are hundreds of benefits and no harm.
It is not obvious when there is only one device now. When more medical devices are developed in the future, especially some high-end large-scale equipment, it will be much more powerful to be tried in a place like the space station than in a hospital.
If the results are good, it is equivalent to a layer of endorsement. When it is promoted to other public hospitals in the future, it will definitely be more convincing.
So he immediately agreed, and then the two sides talked about in-depth cooperation in medicine.
Due to the influence of a series of factors such as strong radiation in space, weightless environment, storage conditions, etc., the efficacy of many drugs will decrease significantly after traveling in space, and many drugs will not meet the prescribed efficacy requirements.
Correspondingly, the shelf life has also been greatly reduced, generally 6-12 months, which is much shorter than the two or three years of ordinary drugs.
In the space station, the activity of many bacteria and viruses can often be greatly improved, and even mutate to a certain extent.
Therefore, the space center wants to conduct medical and genetic research with Sanqing.
Not only can the efficacy and shelf life of some common drugs be extended, but the space environment can also be used to study the genetic variation of organisms.
Sanqing Group has an excellent reputation in the manufacturing and research and development of original drugs and generic drugs, making it the best partner to seek cooperation with. Not to mention that many of the drugs themselves are produced by Sanqing.
As for the biological field, brand-new gene editing technology and gene therapy are Sanqing’s strengths.
"Due to the needs of space travel, such as the three-year journey to Mars and the construction of a lunar base in the future, our current frequent supply model of drugs is not realistic. The long-term demand for drugs must be taken into consideration and reach space as far as possible. Be self-sufficient.”
"Currently, the shelf life of most drugs on the market cannot meet the requirements of space travel. Producing drugs on demand in space may be the best solution to this challenge."
"So we plan to start with some of the simplest drugs and study the effects of microgravity and space radiation on the stability of tablet formulations. Radiation protection will be incorporated into the design of the tablets."
Fang Heng talked eloquently and told everything about the space center's plans.
"The first batch of drugs not only contain active ingredients such as ibuprofen and vitamin C, but also excipients such as silica, magnesium silicate and calcium phosphate, which can be found on the lunar surface."
"Our plan is to alter the interactions between ingredients and drugs to understand the impact of these changes on drug stability."
“If data on drug stability can be collected for long-duration space missions, it will help future on-demand production of drugs in orbit.”
"This is an 'automated airborne pharmaceutical' project. It has just been established and has not officially started yet. However, with your participation, it will surely become even more powerful and progress rapidly."
Wei Kang couldn't help but feel excited. The unique microgravity environment in the space station can enable some scientific research that is limited by the earth's gravity to develop and achieve new breakthroughs.
This is also very important for the life sciences and biotechnology fields.
During the more than 20 years since the International Space Station was in orbit, a total of more than 3,000 scientific research projects in various disciplines have been conducted, with the highest proportion being biological sciences.
It is a pity that China in the past was completely isolated from this research field.
There is neither a space station nor a pharmaceutical giant, and there is no condition to carry out research in the field of space medical and biological fields.
Now, with Sanqing Pharmaceutical and the Tiangong Space Station, the conditions are very mature and we can catch up and accelerate research in the field of life sciences in space.
Not only is it worth trying in the biological field, but even some star-level blockbuster new drugs have contributions from space experiments.
Many large molecule drugs face many technical difficulties in manufacturing, delivery and storage, which are expected to be solved by improving crystallization and purification technology.
Merck researchers have cooperated with the International Space Station and conducted crystallization experiments using macromolecular drugs during space missions of commercial supply services.
They used microgravity experiments to study the effects of sedimentation rate and temperature gradient on crystallization purification.
It was found that under microgravity conditions, settling and convection are reduced, resulting in a crystalline suspension that has a lower viscosity and is more homogeneous than controls on the ground.
Later, the team used a rotating mixer to control variables such as sedimentation rate and temperature gradient to induce nucleation and control crystallization, successfully replicating uniform crystalline suspensions in space in ground experiments.
This is of great significance to the purification and storage of macromolecular drugs. If it can be widely used, macromolecular drugs will be converted from intravenous injection to subcutaneous injection, which can greatly improve the quality of life of patients.
In addition, the space environment can also provide meaningful data for clinical trials and provide a comparison for trials on the ground, becoming a perfect reference.
Now, he has a ready-made new drug that is perfect for physical problems caused by the space environment.
Thinking of this, Wei Kang glanced at the table and picked up a laboratory report.
This is a clinical phase I experimental report of a bone resorption inhibitor.
Data show that this new drug can inhibit bone resorption and has a strong therapeutic effect on osteoporosis and other related diseases.
As for the disease of osteoporosis, no one has experienced it more deeply than astronauts.
In space, astronauts are exposed to microgravity conditions for a long time, and their bodies will undergo a series of changes, which can induce some potential diseases. The most prominent problem is osteoporosis.
Under normal circumstances, bones maintain a balance of bone mass through the interaction of bone formation and bone resorption.
However, in a microgravity environment, because bones no longer need to resist the action of gravity, the reduced load will lead to increased bone resorption, leading to osteoporosis.
While physical activity can provide relief, it does not completely eliminate the risk.
The whole process is very fast, and it often takes a few weeks to cause osteoporosis in astronauts. Unlike on the ground, osteoporosis is rare in young people and more common in the elderly.
There is no doubt that astronauts who are strong and resilient will be very suitable candidates for drug testing.
And the space environment is also a perfect place for clinical trials.
Healthy people will develop symptoms of osteoporosis within a few weeks of treatment. They can test the effectiveness of the medicine while taking it.
You can recover quickly after you get it off, so you don’t have to worry about the sequelae.
Isn’t this better than what old ladies in their 60s can do?
The moment this idea came up, Wei Kang said it directly to his phone.
He can be sure that the other party will definitely be interested.
"There is a new drug, a bone resorption inhibitor for osteoporosis. I think you should use it."
"I wonder if your astronauts are willing to give it a try?"
