Kunming City, Sanqing Headquarters.
The office door was knocked open with a bang.
Wen Renlong rushed in with an indignant look on his face and shouted loudly.
"Old Tang, have you heard about the Nobel Prize? These grandsons are really bullying people. They dare to block the scientific researchers of Sanqing. They are just being rogue. It's really a pity for Old Chen this time. He is obviously a A man who is known as a king will be humiliated by a bunch of pigs."
He was so angry that he was trembling all over: "If I were in Carolinian College, I would grab those dog pens and kick them one by one, so that they would have no descendants."
Tang Que turned his head and looked at him expressionlessly: "Are you done?"
"Brother Que, didn't you even respond?"
Tang Que sneered: "Are you still too naive? Haven't you seen through the academia in all these years? They have spent hundreds of years cooking a big pot of fat. How can you eat it without wagging your tail vigorously?"
Wen Renlong sat down opposite him angrily: "Brother Que, I understand the truth. I'm not angry."
Tang Que turned his gaze to the computer and said calmly.
"If you care about the Nobel Prize, you should just stay abroad. Just like that Zheng Feng, wouldn't it be good to gain both fame and fortune?"
"By the way, that Zheng Feng has done so much and yet he didn't win the Nobel Prize."
"You see, we are not allowed to eat anyway, so there is nothing to be angry about. The only way is to start a new business and play our own game like the boss said."
Wen Renlong's eyes lit up and he said, "Is the boss going to make a big move? What did he tell you?"
"It's nothing, I guessed it myself." Tang Que said calmly: "By the way, have you received the results of your anti-AIDS drug CCR5 antagonist?"
Wen Renlong said proudly: "I, Aaron, will succeed immediately if I take action. The CCR5 antagonist has been developed, but I have a new idea."
"Isn't cocktail therapy popular for AIDS now? I am currently developing several other viral inhibitors, and plan to combine reverse transcriptase inhibitors, protease inhibitors, and fusion inhibitors to inhibit viral replication to the greatest extent. Achieve 100% success rate.”
A playful smile suddenly appeared on Tang Que's face.
"It sounds like your CCR5 antagonist drug binding rate is not very high. How much is it? Is it 60%? Judging from your shit-eating expression, it can't be only 50%."
Wen Renlong slapped the table and said angrily: "You underestimate me too much. At present, the new drug molecules have reached more than 80% CCR5 protein inhibition rate, but it is just lower than what I promised to my boss, and the adverse reactions are also a bit serious. I'm still continuing to improve the molecular structure, so..."
The more he spoke, the lower his voice became, until finally, it was almost inaudible.
Tang Que rolled up his sleeves and said with a serious face: "If you didn't tell me earlier, I will teach you. Have you only considered small molecule antagonists now? Have you tried biological macromolecule drugs? Combining the two should be able to achieve More than 95% CCR5 protein inhibition rate."
"Macromolecule antagonist?" Wen Renlong's eyes flickered and he said, "This is relatively unstable and easily degraded in the body. It also requires injection, which is very inconvenient. I haven't reached this step yet."
"But it is safe and has no toxic side effects. Small molecule antagonists have good stability, but are easy to become drug-resistant and have high adverse reactions. If we combine the two drugs, we can achieve the effect of 1+1>2. "
Tang Que calmly analyzed: "The administration method of macromolecular drugs is also very flexible. If small molecule absorption enhancers are added to them, it can increase the pH value of the stomach, making the peptide antagonists immune to the influence of gastric acid. On the other hand, it can also promote rapid absorption in the stomach and greatly enhance bioavailability."
"We can try oral administration first and add some small molecule functional excipients to enhance absorption. If that doesn't work, we can use transdermal administration like insulin. I believe there are more solutions than difficulties and it can definitely be solved."
"If both large and small molecule drugs can be administered at the same time, with large molecule peptide antagonists taking the lead and small molecule antagonists supplementing, the efficacy can be maintained for a long time. Not only can the CCR5 protein inhibition rate be greatly improved, but the dosage of small molecule antagonists can also be improved. can reduce adverse reactions and drug resistance.”
Wen Renlong slapped his thigh and said, "That's great, Brother Que, you know more about biology than I do. We brothers work together and are as sharp as gold. With you joining us, we will definitely be able to produce results immediately."
Tang Duo nodded: "I'll put aside the work I'm doing and let's research anti-AIDS drugs together."
A chill flashed in his eyes: "This disease is very popular abroad. With this medicine in hand, I am not afraid that they will come to me without asking. Thinking about it, I am really looking forward to it."
****
Meanwhile, the Neuroscience Lab.
Zhang Li looked at the chat history on the screen and was stunned.
The fact that Sanqing's R&D team was blacklisted by the Nobel Committee and Chen Yiqing was expelled from the Nobel Prize has been widely spread within the company.
Although it was all gossip, everyone told it as if it were true.
When she first saw it, she thought it was incredible. How could the Nobel Prize be so dark?
Being expelled at every turn is for such unfounded reasons. This is something only academic hooligans would do.
How could the dignified Nobel Prize Committee do such a thing?
It's unbelievable.
But her colleagues talked a lot, and she was a little hesitant.
After thinking about it, she couldn't help but think of her teacher, Professor Du Lun at Wudu University.
Professor Duren’s mentor is also a Nobel Prize winner. He is highly respected and participates in Nobel Prize nominations every year.
I think the teacher should know the inside information about the Nobel Prize nomination.
Some real inside information, not the gossip and rumors flying around.
She hesitated for a while, then got up and walked to the corridor, dialing Professor Duren's number.
There is an eight-hour time difference between Fog City and Kunming City. It was afternoon here, and Professor Duren must have just woken up.
The call was quickly connected, and Professor Duren's loud and cheerful voice came from inside.
"Dear Lily, long time no see. I miss you very much. How are you doing?"
"Hello, Dr. Duren, I've been very busy at work recently, but I'm very happy working here. Thank you for your concern."
The two exchanged a few words, and Zhang Li got straight to the point.
"Teacher, I have something to ask you. Well, there is a rumor about the Nobel Prize recently. Have you heard of it?"
"Is it the rumor about Dr. Sanqing Chen's Nobel Prize? Of course I have heard of it."
Zhang Li felt nervous and asked quickly: "I heard that Dr. Chen was removed from the Nobel Prize Committee? Is this true? Isn't someone spreading rumors?"
"Oh, dear Lily, of course it's true. Who would make a rumor about the Nobel Prize? If you make a rumor, it's also a rumor about an entertainment star. You really know how to joke." Professor Duren laughed happily. He admitted the authenticity of the rumors.
Zhang Li was stunned and couldn't move her tongue when speaking English.
"Is this actually true? Why? Aren't Nobel Prizes always fair?"
Professor Du Lun chuckled and said: "I can't tell you the specific reason. The teacher didn't reveal much to me, but I can assure you that it is true. What, I told you before that you have no future in Sanqing. "
"Do you want to consider coming back to study for my Ph.D.? With your excellence, you will soon be able to publish several of your own "Cells" under my guidance. Then you can stay in my laboratory and study together in the field of neuroscience. Show off your skills..."
Before he could finish speaking, he was interrupted by Zhang Li.
"Then is it possible for me to win the Nobel Prize?"
Professor Du Lun was stunned for a moment and then said with a smile: "If you leave Sanqing and come to my laboratory, and you can really make such high achievements, your instructor will definitely nominate you for the award."
"Haha, I understand." Zhang Li already got the answer she wanted, so she stopped asking any more questions and directly changed the topic.
However, after hanging up the phone, her face was gloomy and her brows were furrowed.
"Sure enough, I was too naive to think that the rumors were rumors. Fortunately, I got confirmation from the teacher today."
"From what the teacher said, this Nobel Prize is just like the one awarded by his family. How is this different from an academic monopoly?"
"Only those in your own circle who have made achievements can be recognized. Otherwise, they will be suppressed, denied, and blacklisted."
"I am ashamed to be associated with such a circle of academic hooligans. My decision to leave was very correct."
"In the future, I will continue to stay in Sanqing, keep working hard, and continue to make achievements, so that I can be worthy of my choice."
Zhang Li clenched her fists and secretly made up her mind.
The only trace of respect and admiration for the teacher in my heart has completely disappeared.
****
Yanhe Vegetative Care Center in the suburbs of Haishi.
Xiang Yong stood in front of the office building and looked out the window, looking complacent.
Not far across from him, a six-story I-shaped building was rising from the ground and was almost completed.
Since receiving the investment from Sanqing Group, Xiang Yong bought the entire nursery center he rented before and started building a new ward.
In the past few months, he has received thousands of applications for admission from vegetative patients.
Therefore, the construction of new wards is imperative.
The construction of the new ward is going very smoothly. It is estimated that it will be completed next month and patients with appointments will be notified to move in.
As a result, the number of patients that the care center can treat has increased from more than 200 to thousands.
Although it is far from being able to meet the needs of patients across the country, it should be able to greatly alleviate the needs of the Yangtze River Delta.
Of course, he was not idle during this period. He also inspected several inland provinces and opened several branches in provincial capital cities.
Fortunately, he has rich experience and is a Sanqing cooperative enterprise, so the medical qualifications were obtained fairly smoothly.
According to his plan, branches will be opened in five cities including Yangcheng, Shashi, Chengshi, Jingcheng and Xijing this year.
In the next few years, we will strive to have a branch hospital in every provincial capital city. Of course, some more remote cities will not be counted. It must be calculated by region.
The addresses of these branches are all located in the suburbs, and the monthly care prices are several thousand yuan. They can also introduce medical insurance, and Sanqing will also provide drugs at discounted prices.
Generally speaking, the cost of treatment will be kept at an approachable price and try not to cause too much financial burden to the patient.
In this regard, Xiang Yong is still very confident. Backed by Sanqing Group and located in the suburbs, it has a great cost advantage.
There is no need to worry about the source of customers. Since Yanhe Day Care Center has become famous, Haishi Headquarters receives a huge number of consultation calls every day, which is a steady stream.
Vegetative patients from all over the country are gathering here if they have the conditions.
Mainly due to the hard-core propaganda of car god Schumatz and the too loud brand of Sanqing Group’s official cooperative unit.
Wei Kang was also very satisfied with Xiang Yong's speed and felt that he had indeed seen the right person.
In a short period of time, not only can we expand the main hospital, but we can also set up several branches. This ability is quite outstanding.
He is quite confident about the chain of daycare centers in the future.
Making money or not is secondary, the main thing is being able to treat more and more patients.
In this way, Sanqing's hard work in developing drugs also makes sense.
****
Shenzhen City, Ritz-Carlton Hotel.
In a luxurious banquet hall, investment elites in suits and leather shoes gathered together, drinking glasses, and the atmosphere was extremely warm.
This is a celebration dinner held by Penguin Investment Department, and some big names in the investment circle are invited.
Liu Ping was sitting at a table where colleagues from Sequoia Capital and many other investment institutions were chatting animatedly.
At this moment, after three rounds of drinking, he was so drunk that his ears were hot and his face was flushed.
A colleague came over with a glass of wine and said: "Mr. Liu, your project is very big this year and the profits are high. Many people are envious of you."
Liu Ping said with a smile: "What the hell, our project investment is small, how can we compare with you? I heard that you don't even look at projects worth hundreds of millions."
My colleague came over with a smile and asked, "Don't try to beat me. It's a project invested by the VPs, not a general like me."
"I heard that there is a dark horse among the projects you invested in this year. That vegetative care center project made a lot of money in the first year. The prospects are very good, and the news has spread in the circle. Our company is also very impressed. Interested, I wonder if there are any cooperation opportunities for the second round of investment?”
Liu Ping glanced at the other party meaningfully and said with a smile: "Of course, but it also depends on whether you have the resources. The most important thing for this project is to bring funds into the group. There is no shortage of money."
Colleagues got closer: "We have an overseas background and have cooperated with some of the world's top medical institutions, so we can attract a large number of high-quality high-end customers."
"As you know, people with brain diseases now have to come to China for medical treatment. This is a huge market, and it is also a blue ocean with a promising future. There are basically no strong competitors. How much can be grabbed depends on quick eyes and quick hands."
"Everyone has reached a consensus. It is estimated that exports will be difficult to liberalize in the past few years, so medical treatment in China is a hot topic, and everyone is gearing up. Since we are all very interested, we have the money and strength to contribute. , let’s make money together.”
Liu Ping said thoughtfully: "We also have overseas investors in the first phase of investment. They have medical resources in Europa. Please tell us more carefully and see if we can complement each other."
The colleague whispered: "We are mainly resources from the Eagle Country. In fact, the demand for patients is huge, but it is severely restricted. The black market prices have reached sky-high prices. Only the rich can afford it. So the middle class and some high net worth People are very excited to come to China for treatment, there is a lot of potential in this field."
"Of course, we also have resources in Maple Leaf Country, Tianzhu Country, and Latin America."
Liu Ping nodded with a deep expression, raised his glass and said, "It sounds very attractive. Let's exchange business cards and come to the office tomorrow to discuss it in detail."
The glasses collided with each other, making a crisp sound.
The two looked at each other and smiled, instantly reaching a tacit understanding.
