Chapter 137 Clinical Results of Male Contraceptives

Style: Science Author: Riding a pig to dig a holeWords: 3859Update Time: 24/01/12 20:04:28
Regarding contraceptive pills, Wei Kang also did some research and understanding before being willing to develop the project of male oral contraceptive pills.

Contraception has always been an old topic. Before the invention of birth control pills, although condoms could also prevent women from getting pregnant, the right to use condoms was more in the hands of men. Therefore, women still endure the consequences of repeated pregnancies.

It was not until the invention of norethindrone, a female oral contraceptive, that women truly took the initiative in controlling their fertility and changed the family and career choices of modern women.

Nearly 60 years have passed since oral contraceptive pills for women were approved for sale.

However, female contraceptive pills have many side effects, such as headache, dizziness, breast pain, abdominal pain, nausea, etc., and are also contraindicated in some patients with other diseases.

Moreover, although there are a variety of female contraceptive methods available today, there are still as many as 85 million unintended pregnancies in women around the world every year, about 50% of which end in artificial abortion. The number of induced abortions in my country is as high as 9.6 million every year.

Therefore, it is also of great significance for men to take contraceptive measures to prevent miscarriage caused by unwanted pregnancy.

Condoms and vasectomy are currently commonly used on the market for male contraception.

However, the reversibility of vasectomy is poor, and although condoms are very reversible, their use requires self-discipline, and it is easy to ignore this step when the passion is intense.

Therefore, for men who do not wish to use condoms or vasectomy, male contraceptive pills undoubtedly have an important role.

The research and development of male contraceptive pills has been going on for decades.

Male contraceptives mainly include hormonal contraceptives and non-hormonal contraceptives.

Hormonal contraceptives mainly act on the pituitary gland and hypothalamus, thereby inhibiting the production of sperm in the body, reducing the number of sperm, resulting in oligospermia or even no sperm and inability to conceive.

This is a rather troublesome thing. After all, men have a lot of sperm. It seems very difficult to kill thousands of sperm without any side effects and to restore fertility quickly after stopping the medication. Something difficult to do.

Therefore, hormonal contraceptives are generally expensive and inconvenient to use, and due to problems with their mechanism of action, they are prone to decreased ejaculation or sexual dysfunction, so further research is still needed.

Non-hormonal contraceptives may inhibit any part of the sperm production process, or they may target sperm maturation, motility or release. Because of its advantages such as high specificity, low side effects, and reversibility, it is favored by researchers.

There are currently several non-hormonal contraceptives under research around the world, such as triptolide and gossypol, which are very promising, but they still need the support of large-scale clinical trials and have not been officially launched.

Some surveys on the acceptability of male contraceptive pills at home and abroad show that as long as they are safe and effective, more than half of the respondents expressed their willingness to accept and use oral contraceptives, and even more men hope to control their sperm.

Therefore, if male contraceptive pills can be developed successfully, the market prospects are quite broad.

So far, there are 18 officially recommended contraceptive methods, but none of them can completely achieve 100% contraceptive effect.

Contraceptive pills should meet three basic conditions: safe, effective, reversible, affordable, and easy to use.

This male oral contraceptive pill from Sanqing perfectly meets the above requirements.

It mainly acts in the early stages of sperm production. Its components can remove a key protein in sperm, so although the sperm can still reach the female uterus, it cannot fertilize the egg.

Moreover, its side effects are very small, except for slight weight gain, it does not affect hormone levels, nor does it affect men's sexual function and sexual function.

What is even more surprising is that it is highly reversible and convenient. If you want to restore your fertilization ability, you only need to stop taking the medicine and it will return to normal after two weeks.

The effectiveness can reach 99%, and the remaining 1% is attributed to the legendary force majeure.

According to animal experiments, after taking the new drug, the mice continued eating and mating as usual without any side effects.

The clinical phase I and II experimental reports also confirmed the safety and effectiveness of the drug.

This new drug is an oral tablet that can be taken once a week for adult men. It is simpler and easier to use than injections, patches, subcutaneous implants and other methods.

Since it does not protect against sexually transmitted diseases, it is targeted at men with regular partners.

However, before male contraceptive pills really enter the public eye, are men really ready?

Wei Kang is not sure about this either.

The results can only be obtained after the male contraceptive pill is actually launched.

After all, no matter how good the words are, if you want to know what men really choose, you have to look at sales.

Wei Kang looked at the clinical trial report and nodded with satisfaction.

"It's great. These drug testers must have spent a lot of money to hire them."

Wen Renlong chuckled: "Actually, it's not bad. Most of them are middle-aged couples who are married and have children. They are the target customer group of this drug, so it doesn't cost much to find them to try the drug."

"There are also young people who have just gotten married and do not want to have children for the time being. These young couples are really concerned about safety, so the cost of asking them to test the medicine is indeed a bit higher."

"But our Sanqing's reputation is here, and we also signed a high compensation treaty. Even though it took a while, we finally got the number of people together."

He was in high spirits, his face was shining, and there was a kind of contentment in his expression, as if he was wagging his tail crazily and shouting, boss, look at how good I am, praise me.

Wei Kang smiled slightly and praised: "Well done, you are the smartest person I have ever met in my life. This task was originally very difficult, but I didn't expect it to progress so quickly in your hands. It's amazing. You are really born with it." the scientist."

Wen Renlong waved his hands repeatedly: "No, no, boss, you've praised me. I'm not as good as you said. Both Lao Chen and Lao Tang are better than me."

But his bright smile, his hands clasped behind his back, and his head raised and chest raised, revealed his immense confidence.

Wei Kang showed a playful smile and started browsing the report again.

"Why don't I see your drug test data here?"

Wen Renlong's face froze, his eyes rolled, he touched his nose and replied: "My data is ordinary, there is no difference, so it is not specially marked."

Wei Kang laughed and continued to ask with interest.

"It's rare to have a drug tester in front of you, so I'd like to ask you, did you have any special feelings after taking it?"

"Is there anything uncomfortable? Will it have any psychological implications? Will it affect your performance in bed?"

"If it was a voluntary choice, would you rather take birth control pills yourself or let your partner take them? And what are the reasons for doing so?"

"By the way, there is a crucial question I haven't asked yet."

"Do you have a regular partner?"

This series of questions caught Wen Renlong off guard. In his impression, Wei Kang was the kind of person who rarely talked about personal matters. He never expected that he would suddenly burst out of curiosity and ask so many questions in one breath.

It doesn't matter if he answers or doesn't answer. Even if he answers, it's hard to go into too much detail.

Suddenly he said with a sad face: "Boss, do you have so many questions? How about I go back and write you a drug test report?"

Wei Kang shook his head: "Forget it, I'll just ask you a random question. If you don't want to answer, forget it."

"It's just that I heard that you have always been single, so I was a little curious."

Wen Renlong smiled awkwardly: "Well, boss, a man as clean and self-sufficient as you is really rare. You are worthy of being a role model for our generation. Unfortunately, I have been corrupted by the sugar-coated bullets of capitalism for too long, and I really can't be like you."

Wei Kang suddenly understood and said with a smile: "Then please be careful, this contraceptive pill cannot prevent the spread of diseases."

Wen Renlong scratched his head: "Don't worry, I, Aaron, have been in love for many years and I haven't had any trouble yet."

Wei Kang asked no more questions. After reading the report, he found that he had indeed done a good job and was impeccable in all aspects.

"The third clinical phase requires thousands of people to test the drug, which is more difficult and takes longer. Are you confident?"

Wen Renlong said seriously: "I have also asked people who came to test the medicine about this, and their feedback results are all very positive."

"It is not only convenient to take, but also effective and has no side effects. It is not troublesome to restore fertility, as long as you stop taking the medicine."

"The contraceptive measures they used before basically required the woman to take the medicine. Now that the man is taking the medicine, the man is very motivated. The most important thing is that the woman is very motivated. She has been urging the man to take the medicine on time and even wants to continue. Participate in subsequent clinical trials.”

"So this medicine is very attractive to both husband and wife. To persuade people to try the medicine, I think that in addition to starting with the man, we can also try to persuade the woman, so that the effect can be achieved faster. I am still very confident in this aspect. of."

Wei Kang showed appreciation in his eyes: "Yes, let's do it this way. I'm waiting for your Phase III clinical report."

Wen Renlongzhi left with great satisfaction and returned to his office.

I just sat down and took a drink of water but haven't swallowed it yet.

The door was pushed open violently and hit the wall with a clang.

Wen Renlong bulged his mouth, looked up, was stunned, and secretly screamed.

Sheng Changya walked in angrily and slammed the door.

She put her hands on her hips, stared at Wen Renlong with wide eyes, and sneered.

"Tsk, tsk, Brother Aaron, you did a good job, but you made me miserable."

Wen Renlong rolled his eyes and looked confused: "What's going on? Sister Changya, why are you angry?"

He stood up quickly and poured tea and water for Sheng Changya: "Don't be angry. Brother, did I do something wrong to make you angry?"

Sheng Changya rolled his eyes: "Don't do this to me. Didn't you two have a good relationship with the girl I introduced to you last time? Why did you suddenly dump her?"

The more she talked, the angrier she became: "Why don't you pick up girls and deal with the aftermath yourself? It's so annoying that she comes to me and cries to me every day. I don't want to take care of this mess of yours, so you can deal with her yourself."

Wen Renlong looked embarrassed and complained: "I didn't expect it. I already gave him enough money, so I thought everything would be fine."

He laughed dryly: "I really didn't expect that she would come to you. It's my fault. I'll treat you to dinner later and apologize."

Sheng Changya spat: "Bah, you scumbag, why did you just give up after all?"

Wen Renlong spread his hands and said: "When you fall in love, it's normal to have separation and reunion. Besides, I agreed from the beginning that I couldn't have a heart-to-heart relationship with her, so I had to have a kidney transplant. In the end, she couldn't afford it. It's my fault." Really?"

Sheng Changya gritted his teeth and said, "You are such a scumbag and so confident."

Wen Renlong sighed and said: "I didn't lie to her. I could tell at a glance that I wasn't suitable for her, so I made an agreement from the beginning. And I didn't treat her badly. I gave her a lot of bags and gifts. It's her. I think too much and can’t bear the result.”

"I don't even think about it, can a woman be able to tie up such a charming man like Aaron? Haha."

Sheng Changya said curiously: "You have quite high standards. After all, I am also a small star. I have to have good looks, good figure, good temperament and conversation, and I am very obedient to you. Why do you dislike me like this?" Already?"

Wenrenlong said proudly: "You don't understand. What you said are all superficial, and they are just clouds to me."

"Only a woman with a mind as sexy as mine can have the honor of conquering me."

Sheng Changya looked like she was vomiting: "Ugh, I can't stand this narcissist like you. Why don't you look more handsome and have a higher income, and you act like a prodigal in love?"

She suddenly sneered and said: "Fortunately, I already knew your character. It's not a waste of money to introduce this girl to you. You two are really a scumbag and a prodigal, a perfect match. Don't worry, I'll take care of this for you." .”

Wen Renlong's face turned dark instantly: "What do you mean? This girl is not a good girl even if she is with you?"

Sheng Changya suddenly burst into laughter: "What do you think, with your reputation as a wanderer, I dare to introduce you to a good girl? Isn't that a scam?"

"I originally thought that this girl had some tricks up her sleeve and could win over this golden bachelor like you, but it turned out that she was a bit shallow. What a pity." She shook her head, as if she was very regretful.

Wen Renlong said with a straight face: "Then you are just acting when you come to settle accounts with me in anger?"

Sheng Changya smiled and said, "Hey, it's not acting, it's watching a show. Sister, I just play. Okay, enough playing, I'm leaving now."