When Wei Kang first saw the FDA ban notice, he was completely confused.
What the hell?
I haven't applied to FDA yet?
Why did you ban my medicine first?
In order to prevent the abuse of painkillers, hasn't your FDA always encouraged the development and marketing of non-opioid painkillers?
What's going on with this duplicity? Sure enough, it is an old and famous double standard.
At first, he thought that foreign pharmaceutical giants were secretly obstructing it. After all, the market for painkillers was so huge that it was normal and reasonable for this kind of attack on competitors to happen.
However, when he saw Du Cheng's clinical trial report on drug treatment, he suddenly understood and came back to his senses.
"Haha, then give up the Eagle Country painkiller market. You asked for this."
The only country in the world where opioid painkillers are abused is because doctors are prescribing painkillers for any disease in order to make money.
Other countries have stricter controls in this regard, so the abuse is not serious and there is a huge demand for non-addictive analgesics.
Like the European nation of Gaul, which is the country with the lowest consumption of heavy opioids, access to these drugs is not easy for patients. All opioids have long been banned from free sale and can only be used with a prescription, and prescriptions for severe opioids are only valid for 28 days.
Some Gauls even went so far as to forge prescriptions or order them online to get the dose of painkillers they wanted. Studies show that more and more people are getting these opioids from veterinarians by harming small animals.
The drug regulatory agencies of the European countries are obviously relatively clear-headed, and it is only in the weird Eagle country that addictive painkillers are rampant.
These countries have a strong demand for non-addictive analgesics, and the market is large enough. Sanqing's new analgesics will certainly not be bad in sales.
Overall, in the global pharmaceutical product market, Eagle Country accounts for 40% of the market share, Europa accounts for 22%, Sakura Country accounts for 8%, while China accounts for 20% of the global market share, and other countries together account for the remaining 10%.
Although it is a pity to give up the largest market in Eagle Country, other global market shares also account for 50%.
Europa, in particular, is the second largest pharmaceutical market in the world, and its relationship with Eagle Country is relatively subtle.
Faced with the strong demand for painkillers, it’s hard to say whether they will pay the FDA’s bill.
When Wei Kang thought about it this way, he didn't mind too much about the lost Eagle Country market.
Moreover, this time, in order to open up the markets in Europe and other countries as soon as possible, he decided not to sell high prices overseas.
Although the price will still be more expensive than in China, compared with anti-cancer drugs and the like, the price gap is already very small.
This is because the medical system in Europa is completely different from that in Eagle Country.
Most developed countries in Europe have free medical systems, and in most cases the government finances pay for them.
In this case, the drug price of the pharmaceutical company will be an important consideration. If the price is too high, it will obviously be difficult to enter the free medical system and will only be sought after by wealthy patients in private hospitals.
Free medical care sounds beautiful, but in fact there are many unsatisfactory qualities. The biggest problem is that medical resources are extremely polarized.
Just like the Germanic countries, their free medical care is indeed free, but different levels of medical resources have been split, with public social insurance on one side and private commercial insurance on the other.
There is no doubt that the best doctors in various fields have actively gathered on the side of private insurance.
Many patients have reported that when they make an appointment with a doctor's clinic with the best reputation in a certain field by phone, the first answer they get is that the fastest appointment is already half a year or even a year away. Got a consultation appointment for a week later.
Not to mention those famous celebrity doctors. Their clinics even explicitly stipulate that they only accept patients with private insurance.
In this case, patients go to private hospitals to get the best and latest drugs, while going to public hospitals can only get inferior cheaper drugs.
Therefore, for analgesics, Wei Kang plans to follow the route of small profits but quick turnover, which can greatly recover the loss of the Eagle Country market and at the same time seize the analgesic market as soon as possible.
And when the whole world uses Sanqing's pain relief, patients in Eagle Country can only pitifully endure the ravages of opioids. What will they think when they see this situation?
No matter what they think, it's none of Wei Kang's business anyway.
****
In Germany, the Charlotte School of Medicine at Berlin University is the largest and best hospital in Europe and is ranked among the top five in the world.
The hospital has a history of more than 300 years. More than half of the German Nobel Prize winners in medicine are from here. It can be called the Taishan Beidou in the German medical field.
The director of neurology, Hasman, happily convened a meeting of a group of subordinate doctors.
"Look at this issue of The Lancet and the scientific journal Translational Medicine. They all have clinical trial reports on a non-addictive painkiller."
"The clinical reporting data are perfect and this is the holy grail of pain relief that we want for our patients suffering from a variety of neuropathic pain conditions."
A doctor raised his hand: "We can contact the manufacturer of this drug for clinical cooperation, and they will definitely agree."
Hasman nodded: "Very good, this task is left to you."
"Hopefully, this drug has already started applying for approval from the European Medicines Agency, so that we can see its miraculous effects in Germany soon."
A doctor hesitated and said: "I heard that the FDA seemed to have banned the sale of this drug due to uncertainty about its addictive properties."
Hassman's eyes widened angrily and he shook his gray beard: "What does the FDA have to do with us? Everyone, you are all medical experts. You have to rely on clinical data to speak, don't follow what others say, especially don't listen to the opinions of bureaucrats. Okay, My children, get to work."
The same scene happened in well-known hospitals in Gaul, Bull and other countries.
There is no room for FDA to dictate here, so experts in the medical circle are gearing up and eager to try it. They want to get this magical painkiller as soon as possible and try it on patients.
The overseas branch of Sanqing also quickly submitted a centralized review application for drugs to the European Medicines Agency (EMA).
As long as it passes the centralized review of this scientific review committee, painkillers will be able to be marketed in European countries.
The EMA was very interested in the opioid painkiller replacement program and it was quickly expedited.
Hassman got his wish and used this painkiller on clinical patients.
The magical effect made him pull his beard straight.
"Sure enough, it has the same effect as written in the paper, which is shocking!"
He quickly started using the drug on his patients with chronic neuropathic pain and received unanimous praise.
So, with a mixture of surprises and emotions, a eloquent paper flew to top medical journals such as The Lancet.
A more lively discussion soon ensued.
Because this is the first clinical paper on painkillers by overseas medical experts.
Unlike several previously published papers, all of which were by doctors from China, they were not as authoritative as Hussman.
When the global medical circle saw Hussman's paper, they were completely convinced of the clinical effectiveness of Sanqing analgesics.
With the publication of clinical papers from other top hospitals in Europe, the last remaining doubts about the new painkiller have disappeared.
The doctors in Eagle Country are angry inside at this time. They are not stupid. They have seen the truth hidden under the high-sounding excuses of the FDA.
Therefore, doctors made their own choices after communicating in professional doctor communities on the Internet.
Mayo Clinic, Cleveland Clinic, Massachusetts General Hospital, and Johns Hopkins Hospital have all sent applications for clinical cooperation projects to top hospitals in China.
Haishi, Ruiji Hospital.
Jian Guohua looked at the email on his computer with an expression of shock and disbelief.
"What? The director of the oncology department of the Mayo Clinic wants to bring a team here for exchanges? They also hope to reach long-term cooperation. If appropriate, they also want to introduce some patients to Ruiji Hospital for treatment?"
"Didn't we introduce patients to Mayo in the past? For some difficult and complicated diseases, if patients want to go abroad for treatment, I help them contact people at Mayo."
"Why is it the other way around this time? I really can't understand."
When the doctors from the Mayo Clinic arrived in Haishi, Jian Guohua looked at the team of more than a dozen people and was instantly stunned.
"Am I dazzled? In addition to the director of the oncology department, there is also the director of the neurology department. There are a few others I can't recognize, but they look familiar. I must have met them at some medical industry conference."
After the two sides exchanged pleasantries, they quickly got down to business.
Only then did Jian Guohua find out that it turned out that the sale of Sanqing's painkillers was banned in Eagle Country, so all major hospitals in Eagle Country sent people to China for friendly exchanges and to deepen clinical cooperation.
The most important thing is that many patients with chronic diseases have long-term pain problems, and they are in great need of the treatment of Sanqing analgesic.
The two parties quickly reached a friendly cooperation, and the Mayo Clinic returned home satisfied.
Eagle Country, Cleveland Clinic.
Dr. Joseph looked at the patient in front of him, frowned and remained silent.
The patient panicked: "Dear Joseph, old man, what's wrong with you? Has my condition gotten worse?"
Joseph shook his head: "I can't prescribe you any more painkillers. If you keep taking them, you might become addicted. I've been an old friend for many years, and I can't watch you jump into the fire pit."
The patient suddenly became anxious: "No, please give me some more painkillers. I need them for my headache, otherwise I won't be able to work and live at all. You don't want to see me lose my job and become a homeless person."
There was a look of struggle on Joseph's face, and he said after a while: "Old friend, do you have any vacation plans recently?"
A bright smile appeared on the patient's face: "Hey, how did you know that I recently took a month's leave? By the way, it must be because summer is coming. Our vacation is about to start. Let me tell you, I plan to go to the beach to have a good time. Stay for a month and get a nice tan before coming back.”
Joseph said solemnly: "Don't go to the seaside. Go to China. Only there is the panacea that can relieve you of pain. I just hope you haven't booked a flight or hotel yet, otherwise you will suffer great losses."
The patient looked shocked and said, "Oh my god, why can't I understand what you are saying?"
Joseph explained patiently: "China has a very good painkiller that is not only very effective, but also non-addictive. It can replace drugs like morphine and is very suitable for your headaches."
"Your neurological headache is already being treated. It will take some time to recover slowly. During this period, headaches are inevitable, but I can't prescribe you those addictive painkillers, so you have to go to China to get new ones. painkiller."
"Ruiji Hospital in Haishi is our cooperative hospital. I will pass your case there, where you can get good follow-up treatment. At the same time, we will pay your bill. Don't worry about the cost. The insurance company will pay for it. , everything is perfect, don’t worry, you can still enjoy your vacation in China, I heard it is a beautiful country, your trip will be worthwhile.”
The patient looked confused: "Ah? Really? Do I have to go? Is there a sea in the sea? It sounds like it should be a beautiful coastal city. Okay, I agreed."
Joseph quickly finished everything and sent the confused patient away before he breathed a sigh of relief.
He cursed bitterly in his heart and wiped the sweat from his forehead, feeling exhausted both physically and mentally.
"Damn FDA, you know how to cause trouble for us!"
"I really wish the FDA bureaucrats could understand what it feels like to be in pain all over your body but not be able to take painkillers."
The same scene happened at the Mayo Clinic, the Cleveland Clinic, and so on.
Soon, countless people from the Eagle Country traveled across the ocean to China, taking painkillers and starting follow-up treatment.
The hospitals in China welcomed this pie from the sky very much, and everyone was smiling from ear to ear.
In the past, when domestic patients received medical treatment here, they often felt that their medical skills were not as good as those of foreign doctors, and that many imported medicines were not available, so they went to Eagle Country for treatment. They were even proud of it, thinking it was an achievement in life.
Now, top overseas hospitals are recommending patients to China for treatment.
Not only are the charges high, but the cases are detailed and the follow-up treatment plans are prepared well in advance.
As long as overseas patients come over, lie down in the ward and take painkillers for treatment.
These overseas patients are really willing to do anything for pain relief.
is it necessary? It's just a little painful, but it's not intolerable.
He actually came all this way just to take painkillers. How squeamish!
The Chinese doctors thought this in their hearts and shook their heads, feeling like they had re-recognized the world.
At the same time, I also gained a deeper understanding of the power of Sanqing’s painkillers.
Just when patients in Eagle Country were going abroad for treatment because of unbearable pain.
Davis, the head of the FDA, is in a crazy dilemma.
He suddenly sprained his ankle while running recently, but he was cured quickly after being sent to the hospital.
But after I was discharged from the hospital, maybe because of my old age, my knees started to hurt and became more and more severe.
The doctor told me that it was osteoarthritis of the knee joint, which is a common chronic disease among middle-aged and elderly people. It can only be treated but cannot be completely cured.
He was so angry that he immediately threw his phone down.
Later, I was prescribed some analgesics such as tramadol, but after taking it, it only relieved the pain for a few hours. After that, the pain was still there, and the knee joint was painful, itchy, and swollen, especially when walking, it was almost like walking. It was the same as on the knife, the pain was excruciating.
He had no choice but to go see the doctor again, but what the doctor said after reading it almost made him mad.
"There is nothing you can do about your pain. Only Sanqing's painkillers can be effective. Unfortunately, Eagle Country has banned its sale."
"Have you had a vacation recently? I recommend you go to a hospital in Huaxia for treatment. You can buy Sanqing painkillers there."
