Chapter 222: The perfect thrombolytic drug: RSCA

Style: Science Author: Chief designerWords: 2931Update Time: 24/01/12 13:34:48
BSL-4 laboratory is the highest level laboratory among biological laboratories.

It is generally used to study bacteria or viruses that can cause large-scale serious or even fatal diseases in humans. Well-known ones, such as Ebola virus, smallpox virus, and Vibrio cholerae.

Even more awesome, T-virus and G-virus can be studied here.

Just doing a blood vessel analysis in such a laboratory will definitely be criticized as a waste of resources in reality. After all, there are only about fifty completed and under construction in the world, and only in mainland China. Two seats.

However, in the simulation of the real universe environment, this problem is not a problem at all.

As the scene in his mind changed, Li Mu felt that his perspective had entered a laboratory that looked extremely clean.

The floor is spotless and very hygienic.

In addition to being able to avoid leakage accidents to the greatest extent, the cleanliness here has also reached level 100 - of course, Li Mu can even adjust it to level 0, which means that the air does not contain any dust particles larger than or equal to 0.5 microns.

"It is indeed a level four biological laboratory!"

After Li Mu sighed for a while, he stopped thinking about it and entered the formal experiment.

With a thought, a person appeared directly on the dissecting table next to him.

And with another movement of his mind, the man's body became transparent, and in the end, only the blood vessels remained.

The blood in the blood vessels is still flowing, and the heart is beating.

This is the most perfect blood vessel specimen - probably all medical scientists in the world will be excited after seeing such a specimen.

But now, only Li Mu can see it.

Looking at the complicated blood vessels in front of him, Li Mu groped his chin, "Such a fluid mechanics analysis... is really troublesome."

Even he had a slight headache at this time.

The total length of human blood vessels is about 96,000 kilometers, which is equivalent to two and a half weeks of the circumference of the earth. Analysis of 96,000 kilometers of tiny pipes...

Li Mu must admit that this is indeed very troublesome.

Fortunately, with the help of his brain computer, he already had a deep understanding of the details of this blood vessel specimen.

Because all kinds of data have been calculated by the brain computer and placed in his head.

"Next, let's get started..."

Li Mu raised his eyebrows and then began to analyze.

It must be admitted that different people and different individuals have different blood vessel distribution in the body, so he needs to find a fluid dynamics model that can describe the blood flow of blood vessels in all people through approximate methods.

And this is his ultimate goal.

In the process, these data will in turn help him conduct research on the Navier-Stokes equation.

The combination of actual data will help his research on theory.

In this way, time gradually passed.

If someone were here and saw Li Mu sitting quietly in front of the computer with his eyes closed, they would probably think that he had fallen asleep.

But in fact, he was conducting scientific research in another "real" world in his mind.

With the help of the brain computer, Li Mu's research progressed extremely quickly.

Here, he has unlimited trial and error costs, and can simulate any experimental conditions. For example, he can make the blood of experimental vascular specimens produce various vascular diseases, such as atherosclerosis, or It directly produces problems such as cerebral infarction, hemangioma, etc., in order to observe the changes in blood fluid.

In reality, there are not so many suitable patients for scientists to conduct research experiments.

Therefore, from a certain perspective, only Li Mu can do this.

In this way, he gradually got closer to success.



A month passed quietly.

Germany, in Kingsley Weir's laboratory.

"Finally...it's confirmed!"

There was a burst of joy in the laboratory system, and Kingsley Weir and his assistants all looked happy.

After Li Mu's data analysis and guidance to them more than a month ago, they began to research the possible unknown ingredient.

And now, they have discovered the unknown ingredient and determined its molecular structure. At the same time, they also understand the composition principle of this new ingredient!

"...It can directly promote the rapid increase in plasminogen activator levels, and more importantly, it can also reduce the viscosity of fibrin, thereby improving blood flow!"

After observing such results from various experimental data, Kingsley Weir couldn't help but exclaimed.

In the past, the principle of action of thrombolytic drugs from the first to the fourth generation was basically to increase the level of plasminogen activator, thereby stimulating the activity level of fresh plasmin to increase, and then through the The dissolution of fibrin in the thrombus makes the thrombus disappear.

Thrombus is composed of platelets, fibrin, red blood cells and white blood cells.

Among them, fibrin is the main culprit of most thrombosis. Because it is unfavorable, it can easily combine with activated platelets to block blood vessels.

Therefore, for the vast majority of thrombus, as long as fibrinolysis is allowed, the thrombus can be dissolved.

This is the role of plasmin.

But now, Kingsley Weir is amazed to find that the new ingredient they discovered can not only promote the level of plasminogen activator, but also react with fibrin, which can attach to the fiber. The surface of the protein, thereby making the surface of the fibrin smoother, naturally makes it less likely for fibrin and platelets to agglomerate, causing thrombus formation.

The most important thing is that it can maintain the smoothness of fibrin in blood vessels for a long time, according to their estimates, for at least two years, which means that for at least two years, the chance of recurrence of thrombus will be reduced. For those who For people who are prone to blood clots, this is obviously good news.

Therefore, by virtue of increasing the level of plasminogen activator and making the fibrin surface smoother, this new ingredient will directly become the best thrombolytic drug.

After all, it can not only cure the symptoms, but also prevent recurrence for two years!

"This is simply the most perfect thrombolytic drug given by God!"

One of the researchers said with great excitement.

However, Kingsley Weir corrected him at this time: "No, don't thank God, we want to thank our boss."

"Don't forget, if it weren't for our boss's magical data analysis, whether we could find RSCA so accurately is still a question."

RSCA, is their name for this new ingredient.

R stands for Rehmannia glutinosa, S stands for Salvia miltiorrhiza, C stands for Turmeric, and A stands for Anti-thrombotic.

The extracts of three traditional Chinese medicines: rehmannia glutinosa, salvia miltiorrhiza and turmeric are the main sources of this new ingredient, so they directly named it RSCA.

Hearing Kingsley Weir's words, the researcher was stunned for a moment, and then nodded with deep understanding: "Oh! Yes! The boss is the real God! The God of Mathematics!"

Although it's a bit exaggerated, looking back on Li Mu's data analysis more than a month ago, it was indeed like God's guidance to them.

Kingsley Weir nodded with satisfaction.

It's not that he is licking his boss, but he is actually thanking and admiring Li Mu from the bottom of his heart.

If it weren't for Li Mu, his daughter Anne's physical condition would have gotten worse as she got older, and he would not have been able to return to the laboratory to continue to use his talents and realize his dreams.

What's more, Li Mu's ability was the key to turning him from grateful to impressed.

Every scientist has his own pride, so there are many researchers in biomedical companies who don’t have a good attitude even when facing their bosses. After all, although their bosses pay them, they also rely on them to make money, and even the bosses don’t Know how they make money.

But when the boss became Li Mu, this situation no longer existed.

"Okay! Children, please let me announce now that our experiment has completed a very critical step. Next, we will officially start to try the directed synthesis of RSCA!"

Kingsley Verlaine smiled and announced: "Of course, before that, I'm treating you. Let's go out to celebrate together first, and tell our boss the good news by the way!"

"good!"

In a burst of cheers, they ended today's research and then began to celebrate.

After leaving the lab, they were able to take out their phones and surf the Internet.

But at this moment, someone suddenly exclaimed: "Pfizer officially announced that they have developed a fourth-generation thrombolytic drug! They are applying to the FDA for clinical trials! It is estimated that it will start in a few months."

"What?" Kingsley Weir was stunned.

Pfizer, is it about to be studied?

(End of chapter)