Li Mu couldn't help but be stunned when he heard this sudden call.
Cold Spring Harbor Laboratory?
He had heard of the name of this laboratory because his sister Li Ruyu had told him several times.
This is one of the most famous biological laboratories in the world. It studies the most difficult biological problems in the world, such as nerves and genes. Of course, the study of cancer is also the key research direction of this laboratory.
According to Li Ruyu, this laboratory is a place where most biomedical researchers want to work. After all, the world's top experimental equipment alone can make countless researchers covetous. Coupled with financial support, Even more so.
Of course, having said that, Li Mu does not study biomedicine, so Cold Spring Harbor Laboratory is really not attractive to him.
But the question is - a Wolf Prize winner in medicine and a researcher at Cold Spring Harbor Laboratory suddenly called him and invited him to join Cold Spring Harbor Laboratory?
Li Mu was a little caught off guard.
"Uh... Professor Kleiner, if you can call me, you should know that I am a mathematician. Of course I am also a physicist. Or, it is not unacceptable to be a chemist, but I am not a biologist. Or a medical scientist... So, why did you invite me suddenly?"
"Your papers have been accepted by Cell. Your mathematical analysis in that paper is definitely the best among all the biomedical papers I have read. Even if you are not a biomedical scientist, I am willing to call you As a biomathematician." Adrian Kleiner said: "With your analytical skills, please believe that the cancer that has plagued mankind for so many years may really be solved in our hands! By then we will easily To the Nobel Prize in Physiology and Medicine!”
"Of course - this is not just something that can be described by the Nobel Prize, this is an achievement that will go down in history! You..."
Listening to Adrian's list of honors that he will receive in the future, it seems as if the cancer problem will be solved soon.
Li Mu couldn't help but think, this man must be a skilled painter.
He is especially good at drawing big cakes.
Listening to the other party's skillful painting skills, if it were another person, he might actually be deceived.
But in fact, this kind of pie is really not a big pie to him.
He already has a reputation for being famous in history. At least for now, his name is indispensable in various newly compiled mathematics textbooks on number theory and quantum mechanics physics textbooks.
As for the new basic force of dimensional force, physics textbook editors all over the world have revised their textbooks overnight to add dimensional force.
As for the Nobel Prize or something...
One thing is that as the chairman of the Save String Theory Organization, a large number of Nobel physicists in their organization have expressed that they will nominate him as a candidate for the Physics Prize to the Nobel Prize Committee.
Of course, let alone saving the string theory organization, in fact, the entire physics community now believes that he is qualified to win the physics prize.
If the discovery of a basic force is not enough to win the Nobel Prize, then there probably will be no results that can win the Nobel Prize.
Therefore, having become a candidate for the prize, he really doesn't care about "possibly" becoming a candidate for the Nobel Prize.
What's more - if mathematical analysis is the key to solving cancer, why do we need biologists?
So he interrupted the other party's enthusiasm for painting the cake: "Okay, okay, Professor Kleiner, you are right, but cancer is caused by the mutation of human cells, and there are quite a lot of uncertain factors in it. Mathematics The analysis above can only provide a certain auxiliary effect, and ultimately we still need to rely on biomedical scientists to try to solve the problem in clinical trials."
"No, no, no, please believe me, we will definitely succeed!"
"Sorry, Professor Kleiner, I don't have the idea of developing in the direction of biology yet." Li Mu bluntly expressed his rejection.
"If you think about it again, this is a really cool direction!"
"Sorry, I have other things to do, so I'll say goodbye first."
Li Mu hung up the phone directly.
However, not long after hanging up, the other party called me again.
"Mr. Li, this is cancer! This is really cool..."
Li Mu hung up again and blocked the phone number.
However, just after the operation was completed, another call came in. After the call was answered: "Hello, Mr. Li Mu, this is the Institute of Immunology of the Max Planck Society. We invite..."
"Sorry, you called the wrong number."
Without waiting for the other party to finish speaking, Li Mu replied directly and then hung up the phone.
However, in the following period, his phone kept ringing, all of which were calls from various well-known biomedical research institutes in the world, including the one from the Max Planck Society. , and gave him a lot of punches.
The Max Planck Society has 80 research institutes under its name, many of which are related to biomedicine.
Until the end, Li Mu had no choice but to skillfully turn off his mobile phone.
"Damn, are these people crazy?"
He complained, and then began to wonder, what could make these biological research institutes around the world call him so frantically?
Soon he thought of something.
Only this thing can cause such a situation.
He immediately took out his cell phone - oh, the phone was turned off.
Then change his cell phone. Anyway, he still has a completely private number.
Then he called Li Ruyu directly.
The call was quickly answered.
"Hey, stinky brother, you actually know how to call your sister. Do you miss her?"
Li Ruyu's voice rang from the phone, and Li Mu said, "Yes, yes, I miss you."
"Yo? Your mouth is so sweet today?"
"...I just want to ask, has your project been completed? Has the paper been accepted by Cell?"
"What's 'yours' should be 'ours'. You are still the co-author of this paper." Li Ruyu corrected it, and then asked doubtfully: "But, how did you know?"
Li Mu finally confirmed that it was really Academician Chen Shanping’s topic about immune cells and cancer cells!
He immediately told Li Ruyu, dumbfounded, the many things that had called him just now.
"What? Professor Kleiner from Cold Spring Harbor Laboratory called you? He is the winner of this year's Wolf Prize in Medicine! He actually invited you to join Cold Spring Harbor Laboratory?"
Li Ruyu exclaimed.
Li Mu: "You haven't explained why you didn't tell me."
"I don't want to give you a surprise! Our paper was only confirmed to be accepted by Cell today, but it will probably be published in the journal soon. I plan to tell you the news when it is published."
Li Ruyu chuckled: "This is "Cell"! You are still the first author! And you definitely don't know how important our results are! It is very likely that we have found the decisive key to solving lung cancer cells. In the next period of time, we will all Clinical trials are underway to address this finding."
"The decisive key?"
"Yes! Based on your last analysis results, we conducted repeated observations and studies on more than 30 sets of experiments, and finally determined that the process of immune cells recognizing lung cancer cells does not originate from a single receptor protein. , nor does it originate from a single tumor antigen."
"It comes from a systematic mechanism. This mechanism is a complete set, including not only the recognition of receptor proteins, but also the recognition of antigens, as well as the conditions of immune cells... In short, as long as we It can help immune cells in the human body execute such a mechanism, and lung cancer cells will be easily solved!"
"And this is all thanks to your help!"
"Is that so..." Li Mu still asked, "But what does this have to do with those people looking for me?"
Li Ruyu thought for a while and said: "Old Chen seems to have said that without your mathematical analysis, we would never have discovered this key so easily, or even not at all! This is probably the reason."
"Those laboratories want to cooperate with you, and they probably hope that you can help them analyze the differences in the experimental data."
"In the past, although we attached great importance to experimental data, if we cannot analyze the detailed differences in these data, even if we have data, it will be useless."
"So those people probably think that relying on your analysis, you might be able to discover some important results from the data."
"It's just like us."
Li Mu nodded thoughtfully, and then said: "So that's it, I understand."
"Hehe, it's a pity that you are not in the country. Otherwise, we would have had to come to our celebration banquet last night, and Lao Chen would definitely express his gratitude to you."
Li Mu couldn't help but laugh: "There will always be a chance."
…
Li Mu probably couldn't imagine that a little help he provided at the beginning would have such an important influence on the entire biomedical world.
Their topics are not only of considerable importance to cancer research in terms of results, but their research methods are also innovative and pioneering for the entire biomedical community.
In the next few days, the influence of this paper gradually fermented, until it reached a peak after it was officially published in the journal Cell.
John Fan, editor-in-chief of Cell magazine, made targeted comments on this paper: [This paper is undoubtedly very successful, and it is not only successful in terms of conclusions, it is also very successful in terms of process and methods. success.
In conclusion, it reveals a mechanism for us that we have never noticed before. Perhaps if we want to use immune cells in our body to kill cancer cells, mastering such a mechanism will be the key. Now I have I believe that the solution to cancer cells will no longer be a luxury dream for humans.
In terms of process and methods, I have never thought that our discipline can apply experimental data to this extent. Those seemingly boring data actually hide the truth that we cannot see. I am only good at observing experimental phenomena, but have never been good at analyzing experimental data, but now it seems that I should change my mind.
But the most surprising thing is that the person who did this was actually a mathematician who had never studied biology! 】
Of course, it's not just that. Both "Science" and "Nature" have also cited this paper and placed it under the [RESEARCH HIGHLIGHTS] column, which means current research hotspots.
And both magazines invited Nobel Prize winners in Physiology or Medicine to comment on this result.
James Allison, winner of the 2018 Nobel Prize in Physiology or Medicine, cancer research expert and immunologist, made a very high evaluation: "The results of this paper are very outstanding. It not only reveals how lung cancer cells and A new immune mechanism between immune cells also brings great help to the fight against lung cancer."
"Of course, we are also very clear that this is definitely not the most important. In fact, this is a paper that can change the pattern of our biomedical community. In the past, we may have attached great importance to experimental data, but what we often valued was Experimental data that looks very striking, not these ordinary data."
"But for now, the approach to experimental data in this paper is certainly worth learning from for all of us."
"A petri dish is like a chaotic system. No one knows what happened in it, and it also gives us the feeling that no results can be obtained from the analysis of such a complex chaotic system."
"And this paper proves that's not true."
"As long as the mathematical ability is sufficient, the results of any chaotic system can be analyzed."
"Of course, what I have to ask at this time is, how much mathematical ability is required to achieve the level of analysis in this paper?"
"Oh, do you need to have mathematical abilities like the prover of the Hailstorm Conjecture and the Twin Prime Conjecture to do this?"
"That's okay."
"..."
James Allison's evaluation made every biological researcher smile knowingly after reading it, but after laughing, he felt like crying.
Does one need such strong mathematical abilities to be able to do this?
Oh my God, this is simply killing these biological humans.
If they had that kind of mathematical ability, they would have studied mathematics long ago. How could they study biology?
But at this time, the chemical community next door also had something to say.
The world of chemistry has been through the same thing for a long time.
After Li Mu's theoretical chemistry papers were released, the entire chemical world entered the era of mathematics, and various chemists embarked on the path of studying mathematics.
As a result, when they started studying mathematics, they discovered that this was a path of no return.
I can’t learn, I can’t learn at all.
I don't understand anything at all.
As a result, they now find that the biological world seems to be heading towards this point of no return?
The relationship between biochemistry and biochemistry is very close, almost like that of biological brothers.
What are brothers used for? Of course it's meant to be a trap.
So the chemistry scholars immediately persuaded the biology scholars to study mathematics with them.
The entire biological world gradually began to fall into the pit under the pull of Li Mu's mathematical analysis and his "brothers".
However, Li Mu, one of the culprits, had no idea.
…
(End of chapter)
