When he first went to Beijing University, Li Mu joined Li Ruyu's mentor, Academician Chen Shanping's research group on cancer and the immune system, mainly to provide mathematical help.
After all this time, he finally needed his help.
"good!"
Hearing Li Mu's promise, Li Ruyu nodded, then left the room and came in with a lot of information.
"The data about the experiments are all in these. If you have any questions you don't understand, just ask me."
"Um."
Li Mu took the information and placed it on his already packed desk.
While looking at these materials, he asked: "Didn't you say last time that Academician Chen specially arranged a topic for you? How is your topic going?"
Speaking of this matter, Li Ruyu's face showed pride: "Hey! Once my topic is published, I am afraid it will scare people. I will definitely publish it in one area."
Li Mu thought about the fact that the quality of his graduation thesis must be at the level of the first district...
Finally he shook his head and said with a smile: "Yeah, that's awesome."
"If you have any questions, especially about math, you can ask me."
"Thank you." Li Ruyu waved his hand: "But my subject does not require mathematics for the time being. I can do it by myself."
Li Mu smiled: "Okay, that's good."
Is this the sister who will be strong throughout her life?
Without saying anything more, he looked at the data seriously.
This topic explores the interaction mechanism between cancer cells and the immune system, especially lung cancer cells.
The human body's immune system is very powerful. Immune cells can identify cancer cells and attack them. Therefore, in the biological world, there is also a saying that everyone has cancer cells, and the small number of cancer cells in the normal body are all destroyed by immune cells. Identified and killed.
However, for those patients who have too many cancer cells and have already suffered from cancer, the immune system seems to be somewhat inadequate. And the most important thing is that the morphology of cancer cells is not much different from normal cells, and at the same time, their function It can also actively avoid recognition by immune cells.
Therefore, how to find the key points at which cancer cells can be recognized and attacked by immune cells can help biologists find solutions to cancer.
However, because there are various differences between different cancer cells, they only studied lung cancer cells in this topic.
Of course, considering the number of lung cancer patients worldwide, the value of this topic is definitely not small.
"These experimental data mainly come from the coexistence of immune cells and lung cancer cells in a culture dish."
"We marked the surface of cancer cells and counted various elements in the culture dish, such as metabolites, etc."
"The amount of data is very large and it is very troublesome to analyze. In particular, cancer cells in cancer cell clusters are not always recognized by immune cells, making it difficult for us to analyze what plays a key role in the process."
"So your math help is needed."
While Li Mu was watching, Li Ruyu next to him also introduced the specific situation to him.
Listening to Li Ruyu's introduction, Li Mu nodded slightly, but didn't say anything.
Looking at so much data in this thick document, it is enough to show that the scale of this research group's experiments is very large. It is no wonder that it took so many months to come to him.
There are dozens of groups, each group has hundreds of data.
However, the more experimental data, the better for him.
Because for others, too much data may be more complicated, but with his brain computer, he can analyze such a huge amount of data very easily.
He quickly took out his pen and began to calculate.
Still as before, use the principles of probability and statistics to process these data.
Statistics plays a vital role in many disciplines, such as biostatistics in biology, and statistical mechanics in physics.
While Li Mu was calculating, he was also thinking about related issues in his mind.
Time passed slowly, Li Mu was calculating on his pen, and the computer in his mind was also calculating.
Until the end, something suddenly moved in his heart, and he thought of the problem he was studying.
"Quantum statistical mechanics...The mass of the W boson is equivalent to an equilibrium system, and this mass obviously evolved from a non-equilibrium system."
"In a non-equilibrium system, there must be a key factor that causes the W boson mass to differ."
"So...use inverse quantum statistics to find the cause from the results..."
Suddenly he had a realization, and then the pen that was analyzing and calculating the biological experimental data stopped, and he started another line and wrote down his preliminary thoughts on the inverse quantum statistical method.
Li Ruyu next to him immediately became confused.
She has been watching Li Mu's calculation process, trying to learn something from it, such as Li Mu's ideas.
Not being good at math has always been a pain for her, and now that she has seen her brother become a world-famous mathematician, she wonders, since we are all born from the same mother, can't she save her math skills?
As a result, she also stepped up her study of mathematics, especially those related to biostatistics, so when Li Mu wrote just now, she could barely understand it.
As a result, Li Mu suddenly wrote these things...
What the hell is that?
She asked in a low voice: "Which part of probability statistics are you writing now? Why haven't I seen it?"
"Oh, this, this is quantum statistical mechanics. It's normal that you don't understand it."
Li Mu replied.
"ah?"
Li Ruyu's eyes suddenly widened: "Do we still need to use quantum statistics methods in our biostatistics?"
Stop it!
This is simply killing her!
Li Mu couldn't laugh or cry for a moment, and quickly explained the reason. He just wrote it after temporarily thinking of the content of quantum statistical mechanics, and it had nothing to do with their topic.
Li Ruyu breathed a sigh of relief.
It almost startled her.
"Then do you have any ideas about our data?"
Li Mu squinted his eyes and pondered for a moment, and finally said: "A-23, A-45, A-89... I suggest you repeat the experimental data of these groups several times and carefully observe the reaction process, especially In the details.”
Calculating on paper is actually just his habit. No matter what he is thinking about, the computer in his mind will give full play to its multi-tasking ability and perform multi-thread analysis. Therefore, in such a short period of time, he has analyzed all the data. All over.
Just kidding, at the Institute of High Energy, a six-digit amount of data has been analyzed, but the data they have here is only a few thousand, so there is no challenge at all.
So, he reported the numbers of more than 30 sets of data in succession, and Li Ruyu next to him quickly took out a piece of paper and took notes.
After writing everything down, she asked curiously: "What happened to these data? Is there any difference?"
"According to the analysis, there are obvious differences between the experimental data of these groups and other data."
"Is there a difference?" Li Ruyu glanced at these groups of data. Aren't they all composed of ten numbers?
What's the difference?
Li Mu glanced at her: "You want to hear it?"
Li Ruyu nodded like a chicken pecking rice: "I think!"
Knowing what is happening, you must also know why it is happening. Li Ruyu has always had this attitude in his studies.
Li Mu just smiled: "Okay, I'll explain it to you briefly."
Then he picked up the paper and pen and started writing.
"I don't understand biology, but since these numbers appear here, there must be a reason behind them, and there will always be subtle differences."
"For example, the metabolite indicators of the B-112 group of data may seem to be no different from the metabolite indicators of other groups. The difference in numbers seems to be just the same error. But if we analyze the data of these groups , you can easily find the differences.”
Li Ruyu: "...Really?"
Li Mu: "Then I'll just do the math for you again."
Li Ruyu: "Okay!"
…
I don't know how much time passed before Li Mu's door opened, and Li Ruyu left the room with a confused look on his face.
Oh my god, what was she thinking just now, actually trying to understand Li Mu's thinking?
Although she remembered what Li Mu said, she didn't understand the meaning at all.
This kid still doesn't admit that he specializes in writing heavenly books!
Of course, she didn't understand the process, but she generally understood the conclusions Li Mu gave. All the data Li Mu pointed out showed significant immune reactions.
In other words, if they repeat these groups of experiments carefully, they will likely discover how the immune system recognizes lung cancer cells and attacks them!
She felt excited, this was what their research team wanted to know!
Although she just came back today, she had no intention of resting. She quickly returned to her room, then contacted Academician Chen Shanping and told him the news.
Li's mother Qin Lan was helping her daughter clean up her room at home. When she saw this scene, she could only say: "Don't tire yourself out."
Li Ruyu waved his hand: "Don't worry!"
It didn’t take long for the video conference to begin.
Except for her, who went home early at Chen Shanping's request, everyone else in the research team was still in the laboratory.
So as soon as the video conference started, she saw all her colleagues in the laboratory appearing in front of the camera.
"Ruyu, you must have just arrived home not long ago, right? Has Li Mu finished analyzing our experimental data?"
As soon as the video opened, Li Ruyu's best friend Xin Xin asked the question first.
Of course, this question is what everyone in their laboratory wants to know.
It's impossible no matter how you think about it, right?
However, Li Ruyu just nodded and said, "Yes, he should have almost finished the analysis."
The conference room was filled with "Huh?" sounds.
How can we analyze so much data so quickly?
Is it cheating?
Chen Shanping's expression in the laboratory was also very surprised. They had collected data for several months, and Li Mu analyzed it all in one day?
But soon, he said: "Okay, okay, let's not talk about this matter for now. How is the analysis going?"
No matter what, the result is the most important.
Li Ruyu directly sent over the more than 30 sets of experimental data numbers that Li Mu mentioned.
"Based on Li Mu's analysis, he suggested that we repeat these experiments several more times to observe the reaction process of immune cells and lung cancer cells."
"Is there anything wrong with these groups' experiments...?"
Everyone in the conference room became confused, just like Li Ruyu's behavior before.
Li Ruyu smiled. She had experienced the feeling of being at a loss just now, and of course she wanted to let her classmates experience the same feeling now.
"Are you sure you want to know the reason?" She gave it up first.
However, Chen Shanping interrupted her thoughts directly: "Don't talk nonsense, just say it."
The instructor was dissatisfied, so Li Ruyu stuck out her tongue playfully, and then honestly explained to these classmates the process Li Mu had just explained to her.
Even if she couldn't remember it, she took notes and was able to retell it completely.
But during her retelling, there was some silence in the conference room.
Uh...it seems like there's really no need to listen to this analysis process?
Chen Shanping didn't say anything, a little embarrassed.
However, he still said to other people in the laboratory: "Listen carefully and study Li Mu's analytical thinking. Maybe the mathematics expert in our laboratory will be one of you in the future."
The graduate students in the laboratory immediately rolled their eyes wildly.
cpu!
This is definitely on the cpu for them!
How can this be learned?
But they had no choice but to listen to the instructor and memorize notes at the same time.
In this way, Li Ruyu's narration continued. Although they could not understand the process at first, when the final conclusion was laid out, they finally understood it.
Under very detailed analysis, these seemingly ordinary experimental data revealed very prominent differences.
They were clearly told that these experiments were likely to contain the answers they wanted.
"very good!"
Chen Shanping's eyes showed excitement.
After months of experimentation, we finally see the light of harvest!
Of course, this is also thanks to these analysis results. If they had not seen it with their own eyes, they would not even believe that these data could be analyzed in such a subtle way.
"Li Ruyu, thank you for your hard work. Please also express my gratitude to Li Mu for me."
Chen Shanping said solemnly.
"good!"
Hearing what Academician Chen said, Li Ruyu also smiled on his face.
Brother, awesome!
Without any nonsense, Chen Shanping immediately arranged the next work: "Next, we will repeat these experiments several times until we find the cause of the abnormality of these data!"
"yes!"
Everyone in the laboratory responded immediately.
"Besides, Ruyu, please take a good vacation. Thank you for your hard work."
Li Ruyu chuckled and said, "It's not hard, it's not hard."
Just give her a few more days off.
The next moment, Chen Shanping said: "Then we will go back to the laboratory in the fourth year of junior high school and complete this experiment. Is that okay?"
Li Ruyu's face suddenly became depressed: "...No problem."
The fourth day of the Lunar New Year! The fourth day of the Lunar New Year!
It means that she will go back to school in three days this year.
A certain great god said that the 21st century is the century of biology. Looking at it now, the 21st century is completely a tragedy for biological dogs like them.
…
Time passed like water.
A week passed quickly, and China also ushered in the New Year of 2021.
Li Mu couldn't tell what the relationship between science and tradition was, but at least he could feel the faint joy during the New Year, even though people said that the flavor of the New Year has faded away now.
Three days passed quickly on the first, second and third day of the lunar month. On the fourth day of the lunar month, Li Ruyu embarked on the road back to Beijing.
"No one will go back to school before the new year is over, right? No, right?"
Li Mu personally sent his sister to the airport. Of course, he did not forget to laugh a few words before leaving.
Li Ruyu glared at him, "Looking for trouble, right? It would be rude to say anything else."
Ever since Li Mu knew that she was going back to school early, he would laugh at her every day.
Li Mu smiled and then handed the suitcase to Li Ruyu: "It's time for security check. Go over there. Remember to make a call when you get there."
"Yes." Li Ruyu nodded, took the suitcase, and then said, "Be careful when you go to the UK. Don't go to those weird bars, especially places where men gather."
"Especially don't go to Brighton. I heard it's called the gay capital. It's scary."
"You don't want us parents to raise children, right?"
Li Mu: "...What are you worrying about all day long? Leave quickly, leave quickly."
With that said, he pushed Li Ruyu over.
Soon, after watching his sister pass the security check and waving goodbye to him, he turned and left.
After the New Year, he will indeed go to Oxford University.
He thought about Li Ruyu's last words again, and he couldn't help but take a breath. It seemed that what he said really made sense?
You really need to pay more attention then.
…
The New Year passed quickly, and Li Mu stayed at home until the Lantern Festival.
He will leave on January 16th.
However, on the night of the 15th, he received an unexpected phone call.
Edward Witten.
"Li Mu, when I used Li's expansion to improve M theory and tried to make it backward compatible with low-energy theory, I encountered almost insurmountable difficulties."
"I need your help."
…
[4k8 words in this chapter]
(End of chapter)
