Zhu Youxiao, who had just been vaccinated with cowpox, was quite weak and even developed a high fever for a time, which almost frightened the famous doctor Li Zhongzi who was responsible for his treatment.
After all, vaccination with cowpox is no different from vaccination in later generations, and because the smallpox virus contained in cowpox is not the inactivated vaccine virus of later generations, but only the pox fluid with a small amount of active smallpox virus, so the probability of adverse effects is higher than that of later generations. Much bigger.
However, the mortality rate of smallpox in this era was not inferior to that of SARS in later generations. As the emperor, Zhu Youxiao had to fight if he wanted to avoid premature death due to smallpox.
However, it is undoubtedly an adventure.
The ministers were very worried that something unexpected might happen to the emperor's vaccination.
Yuan Keli even tried to dissuade Zhu Youxiao from trying to vaccinate with cowpox on the grounds that the emperor was in his prime and strong.
However, Zhu Youxiao still insisted on vaccination because he wanted to set an example for the people all over the world who had concerns about vaccination and were not convinced about this kind of immunization method.
Of course, Zhu Youxiao himself knew that historically, the success rate of vaccination with cowpox was actually not low.
Moreover, Zhu Youxiao felt that if he was so unlucky that he could not even get vaccinated against cowpox, then when more severe plagues such as plague appeared later, wouldn't he not even dare to use the immunization method related to these?
Therefore, Zhu Youxiao knew that he had to take a risk and die. Life is often about taking risks.
Many ministers were still worried after hearing that the emperor's high fever persisted after vaccination, and prayed to the God of Pox day and night.
But there are also many people who secretly have other expectations.
Expect some big changes to happen because the emperor was vaccinated with cowpox.
"I hope that the tyrant can die because of this vaccination, but it is a pity that the eldest son of the emperor has not yet been established as the crown prince, and there are no officials in the East Palace yet. There is not even one who can take advantage of the opportunity to practice the power of the dragon. Although the eldest son of the emperor already had a great scholar to teach him, the great scholar taught all the princes of the right age. He was not only the tutor of the eldest son of the emperor, but he was also an unseemly old scholar. The tyrant did this so that no one had the chance to control the eldest son of the emperor in advance. , and then affect his future court situation, he is really shrewd."
At this time, Chen Mingxia secretly talked about this matter to his uncle Chen Bingyi, who was an official in Beijing, outside his pavilion.
After hearing this, Chen Bingyi only said: "For those of us who are officials in the court, have you contacted Zhang Guoji? Although the eldest son of the emperor does not have officials in the East Palace, it is not that he does not have his own relatives! You just say that it is to protect the emperor. The eldest son can successfully inherit the throne in the future, and it is not impossible to ask Zhang Guojiu to promise something. At least he has to test the uncle's tone and listen to his views on the court situation. If he supports lenient punishment and advocating justice, But it can protect the emperor's eldest son's future position. If he doesn't support it, we can make plans early and choose another wise king."
"My uncle means that if the eldest son of the emperor is not suitable to be the king in the future, he should be replaced by another prince?"
Chen Mingxia looked around, and then asked excitedly.
Chen Bingyi just nodded, and then said: "I hope God will show mercy and make great changes!"
"Haha, Mr. Chen, things are about to change. News came from the cabinet that the cabinet ministers entered the palace overnight again. They all looked very panicked. It seems that the effect of the vaccination on the palace is not satisfactory."
Zhang Wenheng, Chen Bingyi's friend in the imperial court, suddenly came over at this time and spoke to Chen Bingyi and Chen Mingxia with excitement.
Because Chen Mingxia was young, he was not very calm, so he stood up immediately: "Really?! It seems that Uncle Zhang Guo needs to find out what's going on as soon as possible."
…
"Many people have been contacting my father-in-law recently. Please take the time to let him come into the palace to talk to him. I don't want to do anything for the sake of Sheji that will make you resent me for the rest of your life."
Zhu Youxiao was speaking feebly to Queen Zhang Yan.
Zhang Yan, who was touching the temperature of Zhu Youxiao's forehead, stopped her hand in mid-air and froze after hearing what Zhu Youxiao said.
"Um."
After a long time, Zhang Yan responded.
The current emperor Zhu Youxiao is extremely weak. Even Zhang Yan, a weak woman, can kill him in an instant.
But Zhu Youxiao is still threatening Zhang Yan.
Zhang Yan still felt the majestic oppression from the emperor.
"Your Majesty, you'd better get better as soon as possible. There are some things that only you can stop. Even if I want to, I can't."
Zhang Yan couldn't help but said next.
Zhu Youxiao pursed his chapped and pale lips, then glanced at her and asked, "Do you really want me to get better as soon as possible, or are you pretending to want me to get better as soon as possible?"
Zhang Yan had a look of sullenness on her face, but she didn't say anything. She just picked up the medicine and said, "Drink the medicine."
With that said, Zhang Yan took a sip herself.
Zhu Youxiao looked at her still fair and beautiful face, then closed his eyes and said, "Don't drink it! Drinking it will have no effect."
"Drink."
Zhang Yan said softly.
"Don't drink!"
Zhu Youxiao said goodbye.
Suddenly, Zhu Youxiao asked again: "Am I ugly now? My face is full of acne."
Zhang Yan pouted slightly: "No matter how ugly you are, you are still your majesty's concubine."
"That's ugly."
Zhu Youxiao smiled and said.
Then, Zhu Youxiao opened his mouth slightly.
After a while, Zhu Youxiao fell asleep and Zhang Yan walked out of the palace.
As soon as Zhang Yan left the palace, Yuan Keli and other ministers gathered around him: "May I ask the queen, how is your majesty?"
"Wang Cheng'en, go and tell Uncle Zhang Guo to see me. This is His Majesty's order."
Zhang Yan did not answer Yuan Keli, but replied to Wang Chengen.
Wang Chengen and Yuan Keli were greatly surprised after hearing this. They instinctively felt that the emperor might be in a bad situation and that the queen wanted to discuss with her father the succession of the emperor's eldest son.
However, Wang Chengen and Yuan Keli, as people who have seen the world, are relatively calm and will not panic because of this.
"My slave obeys the order!"
Therefore, Wang Chengen left here and went to see Zhang Guoji.
…
"My lords, there is new news in the palace. The Queen suddenly sent a message to Uncle Zhang overnight!"
Zhang Wenheng found Chen Bingyi, Chen Mingxia and others here and said.
After hearing this, Chen Mingxia said first, "Really? Does this mean something big is going to happen in the palace?"
Chen Bingyi couldn't hide his excitement and rubbed his hands, asking Zhang Wenheng: "Is the news confirmed?"
"conclusive!"
Zhang Wenheng replied.
After hearing this, Chen Bingyi said: "We must quickly call on all the ministers in the court to enter the palace and ask for an audience with the Holy Emperor! No matter what, seeing is believing. Even if there is a real need to change the emperor, we have to see it with our own eyes."
"That's right!"
Zhang Wenheng echoed.
So, the next day, before dawn, as soon as Zhang Guoji entered the Daming Garden, thousands of officials followed him and shouted: "We want to see the Holy Emperor! We want to see the Holy Emperor!"
After Zhang Yan conveyed her intention to see her father Zhang Guoji, she returned to Zhu Youxiao.
Because Zhu Youxiao didn't wake up.
Zhang Yan dragged her cheeks, looked at him, and murmured: "Your Majesty, why don't you even believe me?"
Zhu Youxiao opened his eyes at this moment: "What were you secretly talking about just now?"
"No, I didn't say anything."
Zhang Yan blushed and denied it.
Zhu Youxiao rolled his eyes at her, then grabbed a piece of her catkin and put it on his forehead: "Is it still hot?"
Zhang Yan stood up after a while and said with a smile: "It's not hot anymore! It's not hot anymore!"
"It's not hot anymore! Your Majesty is not hot anymore! Go and tell everyone outside that your Majesty's fever has gone away!"
Zhang Yan shouted urgently.
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