An egret called "yo yo" and hovered in the sky. It stretched its long neck and observed the silent Twolegs in the valley. Two people were standing in the middle, looking at the setting sun in the west. Dozens of people surrounded the outside, like mountains holding the sun.
Alyssa opened her eyes wide and watched the egret turn several times. She leaned on her lover's shoulder and asked in a worried voice.
"Xulot...the plague you mentioned is so powerful. How should we deal with it?"
Shulot stretched out his arms, hugged the delicate girl tightly, and stroked her gently for a while. Then, he gathered his thoughts and preached again.
"The epidemics are different, affecting various parts of the human body and causing different symptoms. For example, headache, fever, cold sensitivity, cough, bleeding, acne... Therefore, we need to identify specific symptoms to adopt targeted measures. method."
"For ordinary epidemic qi, as long as the body is strong, the food is sufficient, and the yang energy is abundant, it is enough to resist! The human body's immune system will work to resist external invasion. This is that evil cannot prevail over good. Although you are exposed to the epidemic qi and are infected, , but there will be no serious symptoms. For example, in common epidemics, malnourished old people and women are always seriously ill and will be the first to get sick. However, strong and well-fed young adults often have mild illnesses. Or end up getting sick.”
Hearing this, Alyssa nodded to express her understanding. In villages all over the world, priority is always given to the diet of young adults, and they have the most vitality. Then she noticed her lover's choice of words.
"Xulot, you said there are 'ordinary' plagues, does that mean there are also 'dangerous' plagues?"
"Yes! Some diseases are extremely poisonous and spread extremely quickly, so they are extremely dangerous. I know of nine types alone. If any one of them spreads, it can cause tens of thousands of deaths. of casualties!"
Shulot paused and collected his thoughts. Then, he ordered Na Xiu.
"Naxiu, take note of what I say below, they are very crucial!"
"Obey you!"
Naxiu bowed gracefully and picked up the pen and paper again.
"In the east of the world, far away from the sea, there are nine extremely poisonous diseases. According to the degree of danger to the alliance, the first is typhoid fever, the second is smallpox, the third is plague, the fourth is measles, and the fifth It’s cholera, the sixth is diphtheria, the seventh is mumps, the eighth is malaria, and the ninth is yellow fever!”
"Well... Your Highness, how should you write these nine kinds of plagues you mentioned?"
Naxiu remembered half of it and raised her head in embarrassment. These diseases have not yet appeared in the Americas, and naturally there are no corresponding descriptions.
"Give me a pen and paper, and I'll write it myself!"
Shulot stretched out his hand and took the pen and paper. He tried to remember, first wrote about typhoid fever, and then drew a little man. The little man was holding his stomach and had diarrhea, and the feces flowed into the river.
"Enteric typhoid fever attacks the intestines. Symptoms are diarrhea, vomiting, fever, and bleeding. The mode of transmission is contact with feces and contaminated water..."
Then there was another little man, covered in tiny dots, lying motionless on the ground. The villain exhales in the air and flies into another nearby villain.
"Smallpox, the disease invades the whole body, and the symptoms are rashes, pus, and ulcers all over the body. The mode of transmission is respiratory droplets and contact with items used by the other party..."
Later, the new villain's limbs became blackened like the Black Death, and rats and fleas appeared around him.
"Plague, the disease invades the lungs and the symptoms are fever, chills, bleeding, and gangrene. The mode of transmission is through rats and fleas, which spread the disease everywhere..."
The fourth villain also has small dots on his body.
"Measles, the disease attacks the chest and abdomen. The symptoms are red, flat rashes. The mode of transmission is breathing. It is similar to smallpox, but the disease is slightly milder."
When the fifth villain was drawn, Shulot paused. He didn't know much about cholera, but for the next few hundred years, cholera was probably confined to India and was not introduced to the Americas. After thinking for a while, he drew a little man with diarrhea and wrote roughly.
"Cholera, the disease attacks the intestines, and the symptom is watery diarrhea. The mode of transmission is also the patient's feces contaminating water sources..."
Then, the sixth little man has a big neck, and the seventh one has a big mouth.
"Diphtheria, as the name suggests, is a disease that attacks the neck, forming swelling and white patches, and is spread through breathing. Mumps, a disease that attacks the cheeks, forming swelling, is spread through breathing... These two diseases are both killers of children! "
Shulot took a deep breath. He pondered for a while, and then drew a little man posing, with the words hot and cold written next to it.
"Malaria, the disease attacks the liver and directly damages Ihotel. The symptoms are shaking, alternating cold and heat all over the body. It is spread through mosquito bites."
The last villain has red eyes and tongue, and is vomiting and bleeding.
"Yellow fever, the disease attacks the lungs. Symptoms are fever, body pain, red tongue and red eyes. It is spread through mosquito bites."
Thinking of these two serious diseases, Shulot sighed and warned seriously.
"Although malaria and yellow fever are at the bottom, they are no less harmful to the human body than the first seven, and are even more powerful! It's just that they rely on mosquitoes to spread, are restricted by terrain, and occur in hot and rainy lowland rainforests. Invading the Mexica Plateau where the Alliance is located.”
Shulot turned around and looked deeply to the south.
As long as Pandora's box is opened and malaria mosquitoes and Aedes mosquitoes from Africa are introduced to the Americas, malaria parasites and yellow fever viruses will permanently take root in the tropical rainforests. All rainforest residents in the Americas will always have to endure the test of epidemics. This is a natural disaster that no one can change! The only good thing among misfortunes is that neither malarial mosquitoes nor Aedes mosquitoes like the climate of the tropical plateau, so they pose little threat to the heart of the alliance.
"In the far east, there are nine dangerous diseases!"
Alyssa murmured to herself, with worry in her eyes. She held her lover's arm tightly, her voice anxious.
"Xulot, are there any other dangerous diseases? If these extremely poisonous diseases are introduced into the alliance, what should we do..."
"The essence of epidemic qi is tiny life. There are thousands of lives, and there are naturally far more than nine kinds of dangerous epidemic qi in the world! However, these nine are the ones we need to worry about and be prepared for at the moment."
Shulot smiled slightly and comforted his lover.
"Alyssa, the reason why I asked you to take charge of the kingdom's medicine is because I want to treat the prevention of epidemics as the most important thing! The most important thing for the country is to prevent and control the plague. You don't have to be too anxious. For these nine kinds of I also have a method to deal with the epidemic, enlightened by the gods!"
After saying that, Shulot frowned and thought carefully for a while.
According to the type of plague pathogens, these infectious diseases can be divided into two categories: bacteria and viruses. Bacteria include typhoid, plague, cholera, diphtheria, and malaria; viruses include smallpox, measles, mumps, and yellow fever.
For bacterial diseases, the best way to deal with it is naturally antibiotics. However, in this era, due to inefficient culture technology, lack of purification technology, and insufficient observation accuracy, it is absolutely impossible to produce high-concentration antibiotics. However, you can try to prepare a low-concentration penicillin solution. This is not for antibacterial purposes, but for cultivating bacterial strains from generation to generation.
In order to obtain truly effective penicillin, it is necessary to screen Penicillium groups in a long-term and targeted manner. Because Penicillium often secretes antibacterial and nontoxic penicillin and antibacterial and toxic patulin at the same time. Whether crude penicillin can cure or kill a patient may depend on luck. If the non-toxic penicillin is mixed with an excessive proportion of patulin, it will be a poison that can kill people in minutes!
The trial production of usable penicillin does not require much manpower, but it takes an extremely long time. Historically, after Fleming discovered penicillin, he cultivated Penicillium for about ten years. After generations of screening under the microscope, he obtained a suitable penicillin bacterial population, which provided a population base for large-scale industrial production of penicillin.
"The first task. Naxiu, arrange for a few capable people to collect different types of Penicillium from rotten grains and fruits. Then, use sweeter fruit juice to culture Penicillium. The amount of Penicillium accumulates to a certain When it reaches a certain level, add the oil and stir. Pour out the water layer below, and then use charcoal powder to absorb it. Then..."
Speaking of this, Shulot was stuck for a while. He knew that penicillin was soluble in water and could be absorbed by charcoal powder. Next, what is used for further extraction? ...The young man was not sure, so he thought about it and gave vague instructions.
"...Then, use pure boiling water, acidic hot spring water, and alkaline plant ash water to rinse the charcoal powder respectively, then evaporate the water to dryness and crystallize, use rotten meat to test the antibacterial properties, and then use small animals to test Toxicity...take the bacteria with high antibacterial properties and low toxicity and keep them, and culture them again..."
"...??? Your Highness... Your Highness?"
Hearing this, Naxiu's red lips parted slightly, her eyes turned completely blank, as if she had been spoiled...
"cough!"
Shulot coughed lightly, thought for a while, and said again.
"When you are free, you come to me alone. I will take you to do it together...then choose a few patient and careful female workers to repeat these tasks over and over again, and we will do it for ten or twenty years. !”
"Do it for ten or twenty years?"
Alyssa opened her bright eyes wide, a little unbelievable.
"Well! This is a very slow job, and whether it succeeds or not depends on the gift of fate. It will always take ten or twenty years to get preliminary results. If Lozano can burn pure glass, It can be sped up a lot."
After Shulot finished speaking, he smiled, with yearning in his eyes. If we can obtain qualified penicillin within a few decades, it will be a gift from the goddess of fate! After a moment, he recovered his thoughts and ordered again in a deep voice.
"The second task is to sort out the alliance's various drugs, test their ability to treat common diseases, and write them down for backup. For example, tobacco can treat colds, and Wuyu Jade can treat body inflammation... They all It has a certain anti-epidemic and bactericidal effect! There are more than 800 medicinal materials in the alliance’s priestly inheritance, most of which are herbal medicines, and they all need detailed research and sorting.”
"I obey you, Your Highness!"
Naxiu nodded solemnly. Organizing and recording all medications is a complex and sensitive project. Fortunately, for His Highness's sake, the priests shouldn't have much obstruction.
Central and South America are isolated from Europe and Asia. There are all kinds of magical plants and herbalism is very prosperous. Among the thousands of species of plants and trees, there are always drugs that can deal with various infectious diseases respectively. However, it requires systematic exploration and sorting. Historically, it was the indigenous witch doctors of South America who first discovered that the bark of the cinchona tree could effectively combat malaria.
"Hmm... Cinchona tree... we need to start exploring the offshore as soon as possible, to go to the Inca!"
Shulot made a mental note. Then, he looked serious and gave serious instructions.
"The third task is to prepare the first edition of the priest's manual for dealing with epidemics! ....Epidemics breed in patients and can quickly spread to others or flow into rivers and lakes. Therefore, whenever you encounter an epidemic, you must first treat it The patients should be treated and isolated, and their feces should be strictly buried. As for other people, no matter how close they are, they should avoid contact with the patients, drink boiled water, and kill mosquitoes and rats that transmit diseases... In case of serious epidemics, the corpses should be burned and Patients' clothes. Send out warriors to cover their mouths and noses with fine cloth to seal off the affected areas. Even, if necessary, take decisive measures!..."
After hearing the decisive measures, Naxiu's expression became stern, and she seemed to see boundless blood and fire in front of her eyes. She bowed her head and answered respectfully.
"Your Highness, your will is your mortal life!"
Shulot nodded calmly, his face calm. He would take time to complete the epidemic prevention manual in detail based on the common sense of future generations, and prepare the priests in advance. Then, his thoughts changed and he thought that the hot springs he had enjoyed in the past two days had a certain sterilizing effect.
"The fourth thing is to reserve a sufficient amount of sulfur. Mix plant ash and oil, and add sulfur powder to make sulfur soap... Use it to clean clothes or skin, it can be a powerful sterilizer."
The advantage of having many volcanoes in Central America is that there are many sulfur mines where powerful fungicides can be obtained. Burning sulfur powder in places where germs breed; pouring sulfur in lakes where mosquitoes breed... can weaken the spread of certain diseases.
Night has fallen and the sky has been shrouded in darkness. The bodyguards lit bonfires and lit up the valley in the forest. Shulot was lost in thought. For bacterial plagues, various symptomatic herbal medicines are the key to treatment. The Chinese medicine of this era had relatively mature responses to the treatment of enteric typhoid and malaria. Houttuynia cordata decoction is used for intestinal typhoid, and Qinghao recipe is used for malaria, both of which were inherited from medical books of previous generations.
"It would be great if we could cross the sea to the west...to obtain medical inheritance from the Ming Dynasty and obtain Houttuynia cordata, Artemisia annua and other medicinal herbs!..."
Shulot thought for a long time and shook his head gently. If you want to go west across the sea, you must have European navigation technology. Once the Europeans arrived, they would inevitably bring plague. At this critical juncture, American civilization did not have much time and was always in an emergency... After a while, he came back to his senses and once again thought about how to deal with viral plagues.
Viral infectious diseases, including smallpox, measles, mumps, and yellow fever. The one that needs the most attention is naturally smallpox. By this time, the smallpox virus had been raging throughout Europe for many years, causing countless deaths. The first serious infectious disease brought by colonists was bound to be smallpox.
"How to deal with smallpox? ...Then naturally it would be vaccination."
Xiulote thought of a book about the end of the Yuan Dynasty. The protagonist started his career through vaccination, and the method was not complicated.
In this era, the technology that has appeared in the south of China is variolation. The commonly used variolation methods are divided into dry seedling method and water seedling method. The so-called dry vaccine was to grind the scabs that fell off the bodies of recovering smallpox patients into powder, and then blow them into the nostrils of the vaccinated person with a silver tube. The so-called water seedlings are made by grinding acne scabs into powder, then adding water to adjust the humidity, wrapping them in cotton balls and stuffing them into the nasal cavity.
Essentially, variolation is the acquisition of attenuated smallpox virus from recovering smallpox patients, and then transmitting it to vaccinated people who have never had it, causing them to develop less severe smallpox. Once a patient recovers from smallpox, he will never get it again for life. The resistance gained from the attenuated virus can also protect against the unattenuated virus.
The further development of the variolation method used the acne scabs that had been vaccinated multiple times as vaccines. It is equivalent to targeted screening to continuously obtain less virulent smallpox viruses. The least virulent one is the cowpox virus, a close relative of the smallpox virus. But this requires not only Eurasian cattle, but also cattle that happen to have pox.
"The longer the seedlings are propagated, the clearer the medicinal power will be, and the more mature it will be through artificial selection and refinement. The fire poison will be eliminated, and the essence will remain alone, so it is perfect and harmless..."
Likewise, vaccination can be used against measles. As for mumps and yellow fever, Schlott didn't know much about them and had no clear solution.
"The fifth task is to choose a small offshore island far away from human habitation and establish a secret medical center. Research epidemics and trial-produce...variolus and cowpox...Forget it, the alliance does not have an outlet in the East China Sea. This Xiang is just preparing, there is no rush for now.”
Shulot was halfway through his instructions before he retracted his words. Then, he smiled with relief and said loudly.
"Okay, that's it for today's teaching! Prepare the barbecue, we will camp by the spring."
Alyssa blinked. She hugged her lover tightly, feeling the strong heartbeat of the other person, and also felt the man's strong confidence and will. Inexplicably, the soft girl felt a little hot. She looked up at the sky. The clouds covered the moon. Soon there would be an autumn rain that would soak the deep earth.
"Xulot...after eating the barbecue...let's eat avocado!"
The girl's breath was like orchid, blowing into her lover's ear, making him feel like electricity was flowing all over his body.
"I brought some avocado...according to what you said, it can promote the secretion of hormones, and the deer's...The night is very long, let's try it together and explore some new...rituals... .”
"ah?..."
Shulot's body felt hot, and a fire ignited in his heart. He looked at his charming lover, gritted his teeth, and said harshly.
"Even if I don't eat avocado... I can still eat you..."
"Um, really? I don't believe it...hehe."
Seeing this scene, Naxiu raised her eyebrows. She sighed helplessly, made a few gestures, and the warriors dispersed again.
Not long after, the autumn rain fell from the sky with bursts of thunder. And listening to the continuous thunder, the cold female warrior's body became hot and her feet became weak. She looked down and saw that at some point, the ground had been soaked by rain, making it soft and moist.
Happy days are always busy and short. The rainy season has ended, the clouds have been sucked dry by the rain, and the thunder cannot last long. A few days later, a group of messengers came from afar, bringing the latest report from the western kingdom.
The wind rises at the end of Qingping, and the waves form between gentle waves. The autumn harvest in the world has ended, and the storm of war is about to sweep across the east!
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