Gentle classmate Pan didn't want to say anything when he saw classmate Xie, and took the initiative to explore the way ahead: "I think the most important thing is the suitability."
If the glimmer in Cao Yong's eyes nodded to his junior brother's answer, it seems that many junior brothers are also talented.
In a nutshell, Pan’s words refer to areas that are not suitable during organ transplantation. Doctors may be able to use clever methods to make them suitable, which is called suitable.
"Yingying, what do you think?" Pan Shihua asked classmate Xie for his opinion.
Senior Brother Cao and Student Wei looked over as if they wanted to hear what she had to say. Xie Wanying said: "Wherever the appropriate technical limit is, there may be an upper limit for organ transplantation."
This is a further academic interpretation of Pan’s words.
Classmate Wei and classmate Pan’s eyes seemed to be lit up with little stars. Cao Yong couldn't smile.
How to understand what Mr. Xie said?
Let me first talk about the liver transplant surgery that I have seen before. At that time, classmate Xie participated in the operation and provided suggestions. The difficulty the doctors faced during the operation was that the donor liver was too large and unsuitable. It had to be cut into small pieces. This was a problem of fit.
The donor-recipient ratio has always been a basic threshold in all organ transplant surgeries.
Liver transplant surgery has such technical difficulties, and heart transplant surgery also has such technical difficulties.
Is it possible, like liver transplantation, to cut the heart into a smaller size to fit the donor heart? Classmate Xie told Reporter Li that the proportion of a pediatric donor heart can be 2.5 times the size of the recipient's original heart.
Regarding this crux, anyone with some common sense of anatomy knows that the heart cannot be like the liver. The liver and heart are completely different in form, function, and structure.
The overall structure of the heart and its function are closely related. Not the liver. The function of the liver mainly depends on liver tissue. This results in one donor liver being cut into two for two recipients. How could the heart be possible. The donor-to-recipient ratio for a heart is really more stringent than for a liver transplant. Here’s another trivia point: Don’t worry about the donor being too small for liver transplantation. On the contrary, as Xie said, the ratio of the pediatric donor heart should not be less than 0.9 of the recipient's original heart. This shows that the acceptance of small donor ratios is much lower for heart transplantation than for liver transplantation.
Why is this?
The main functional output of the heart is to recycle blood throughout the body. There is no need to worry about a larger donor. This is because many patients who need heart transplants have heart disease, which causes the myocardium to expand and the size of the heart to become larger. The volume of the place that accommodates the heart becomes larger and can accept a larger heart. Of course, the size should not be too big, as this will also cause postoperative secondary hypertension and other problems.
In contrast, a problem caused by a donor that is too small is more difficult to solve: low cardiac output. Many heart disease patients die from this problem in the final stage. If the transplanted heart fails to solve this important problem, the transplant may be in vain.
In practical clinical application, it becomes: try to choose older donor hearts for young children. Female patient selects male patient heart. Male patients should be cautious when receiving a heart that is too small for their body weight.
These are precisely what Xie pointed out as the "suitable" technical limits determine the technical limits of organ transplantation, and they are all difficulties that need to be solved during the operation.
Just in terms of ratio, the threshold for heart transplantation is higher than that for liver transplantation. Heart transplantation is definitely more difficult than liver transplantation, otherwise I would be sorry for the two major surgical specialties.
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Thank you for your support! ! ! Good night, dears~
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