Rabies is an acute infectious disease caused by the rabies virus. It is common in humans and animals. It is more common in carnivorous animals such as dogs, wolves, and cats. People are mostly infected by bites from sick animals.
Clinical manifestations include unique hydrophobia, fear of wind, pharyngeal muscle spasm, progressive paralysis, etc.
The typical symptom is hydrophobia, that is, when drinking water or even hearing the sound of water, the patient will have swallowing muscle spasm and cannot swallow the water. Even if the patient is extremely thirsty, he will not dare to drink water, so it is also called hydrophobia.
Because the symptoms of hydrophobia are more prominent, this disease is also called hydrophobia.
Rabies can manifest clinically as manic or paralytic. Rabies transmitted by dogs generally manifests as the manic type, while rabies transmitted by bats generally manifests as the paralytic type.
Rabies virus belongs to the genus Lyssavirus of the family Rhabdoviridae and is a single-stranded RNA virus. The virus is spread by animals through biting each other.
Rabies is mainly spread by dogs. There is still a lack of effective treatment for rabies. The mortality rate of people infected with rabies is nearly 100%. Patients usually die of respiratory or circulatory failure within 3 to 6 days, so preventive measures should be strengthened.
Rabies virus contains 5 proteins, namely glycoprotein (G), nucleoprotein (N), polymerase (L), phosphoprotein (NS) and matrix (M).
The glycoprotein of rabies virus can bind to acetylcholine, which determines the neurophagy of rabies virus.
The main sources of infection are sick dogs, followed by sick cats, sick wolves, and bats.
After a person is bitten by a sick animal, the virus in the animal's saliva enters the human body through the wound and causes disease. A small number of patients may also become sick due to contamination of the conjunctiva by the saliva of the sick animal.
Humans are generally susceptible to rabies, and hunters, veterinarians, and animal keepers are more susceptible.
After entering the human body, the rabies virus first infects muscle cells, multiplies in small amounts in muscle cells near the wound, and then invades nearby peripheral nerves.
The virus then spreads centripetally along the axons of peripheral nerves to the central nervous system without spreading through the blood, mainly invading neurons in the brainstem and cerebellum.
The virus replicates in large quantities in the gray matter and travels down the nerves to the salivary glands, cornea, nasal membranes, lungs, skin and other parts of the body.
The main damage caused by rabies virus to the host comes from endosomes, which are eosinophilic particles formed by the accumulation of its discarded protein coats in cells. Endosomes are widely distributed in the central nervous cells of patients and are also the laboratory diagnosis of this disease. an indicator of.
Not all people become ill after being infected. The incidence rate of those bitten by sick dogs without vaccination is about 15% to 20%, and the incidence rate of those bitten by sick wolves is about 50% to 60%. The incidence factors are related to the bite site and the location of the bite. The degree of trauma, wound treatment, thickness of clothing and whether vaccination is related.
This is some research information on rabies on Earth that Xu Xian knows. Even if Captain Wang is sick, it is obviously abnormal to bite people so crazily.
Xu Xian suspected that someone was secretly manipulating Agent Wang to hurt people.
Due to the limited information available, Xu Xian could not make a conclusion, so he had to rely on the power of Bai Suzhen and Xiaoqing.
Xu Xian said to Bai Suzhen and Xiaoqing:
"Su Zhen, Xiao Qing, please check the suspicious characters that appeared in Zhenjiang Mansion before and after Agent Wang fell ill."
Bai Suzhen used the element of water and Xiaoqing used the element of wood to restore the whole incident, and the truth finally emerged.
The dog did have rabies, but it had not yet developed an attack. It had been diligently guarding the home. When a child and his mother passed by, the dog barked at them.
The child's mother cursed the dog for scaring the child and threw stones at the dog, which scared the dog away.
From then on, the child came over every day and followed his mother's example of hitting the dog with stones. After this continued for several days, the dog went completely crazy and pounced on the child crazily.
The children wore thicker clothes, and the mad dog just scratched the children's clothes. The children were used to fighting with other children, so they were better able to run. They got up and ran as fast as they could.
After all, the child's physical strength is limited. After running for a while, he lost his strength and was knocked down by the stones on the road.
Detective Wang happened to pass by and saved the child, but he was bitten by a dog and slaughtered the dog.
Then, Agent Wang quickly sought medical treatment from Dr. Zhou, and the strange medicines prescribed by Dr. Zhou.
Xu Xian saw the medicine prescribed by Dr. Zhou of Derentang, and then he realized what quack medicine meant.
If you don't know how to deal with it, just say it straight away, but you don't know how to pretend to understand, which makes Agent Wang's family heavily in debt.
In the more than a month before the onset of the disease, Agent Wang saw how much money was being spent on medical treatment, and he wanted to give up many times. However, Agent Wang's parents persisted, not only spending all their family savings, but also borrowing money from everywhere.
When the symptoms of rabies appeared, Agent Wang regretted it very much. Not only was he in danger, but his parents were also implicated.
At this time, a voice sounded in Dr. Zhou's ears, saying that Dr. Zhou was a quack doctor who misled him, could not treat the disease, and deceived him into spending all his family's savings.
Detective Wang has an obsession in his heart. He wants to kill Dr. Zhou before passing away in order to avenge him for being deceived.
That voice kept ringing in Agent Wang's ears, as if there was a magical power that gave him the strength to kill Doctor Zhou desperately.
At this moment, Captain Wang's eyes lit up. He saw Dr. Zhou and couldn't help being overjoyed. He rushed forward, grabbed him and bit him.
Finally getting his revenge, Detective Wang was overjoyed. He glanced out of the corner of his eye and found that the person he bit was a stranger, and Dr. Zhou was in front of him, showing him a mocking smile.
Captain Wang was furious, rushed forward again, threw the man to the ground, and bit him.
Every time Agent Wang finished his bite, he found that he had found the wrong target, and Dr. Zhou was still in front, still with a sarcastic smile on his face.
Agent Wang quickly used up his last strength and kept throwing himself at Dr. Zhou until he was knocked unconscious by Xu Xian.
Wang Baotou was tied up with five flowers and a ball of cloth was stuffed in his mouth to prevent him from biting anyone again. He was sent to Deren Hall along with those who were bitten.
When Wang Captou woke up and saw Dr. Zhou, he wanted to pounce on him for revenge, but he couldn't move his hands or speak back. He could only stare angrily, as if fire was about to burst out of his eyes.
Doctor Zhou glanced at Captain Wang and said:
"Although Captain Wang has done good things in this life, he can't offset the sins of his previous life. God won't let him go. I've tried my best.
The people he bitten were pitiful.
Wang Captou's few merits in this life cannot offset his heinous sins, and he may not be able to achieve any good results in his next life. "
After being bitten, those who had been bitten originally hated Captain Wang very much, but after hearing Doctor Zhou's provocation, their anger became even more intense.
One person said:
"With Agent Wang's madness, I'm afraid half of the seven of us won't be able to survive. Agent Wang's sin will never be redeemed by death."
One person rushed towards Detective Wang and shouted:
"I will fight with you, I want you to pay with blood!"
"presumptuous!"
Liang Captou swung the knife in his hand and shouted loudly:
"Whoever dares to take action, don't blame me for being ruthless with the sword in my hand."
Seeing the shining sword in the hand of Capt. Liang standing in front of them, no one dared to rush forward, lest they be executed directly for causing trouble.
He attacked the yamen officials and was accused of being a bandit and causing trouble. Even if he was killed, it would be in vain.
Because Fang La's followers really started rebellions in major cities in the south of the Yangtze River, and rebellions often occurred in Zhenjiang Prefecture.
Chu Huizong has issued an imperial edict that in the south of the Yangtze River, anyone who gathers to make trouble, storms government offices, or attacks officials at all levels, regardless of the reason, can simply do so in the name of banditry, and the killing will be in vain.
