"Director Zheng, actually we have an idea about the generation of dizziness.
It's just that we haven't thought of a good way to convert electrical signals into brain nerve signals.
Implantable brain-computer connections are inconsistent with our product positioning.
With existing methods, how to accurately transmit electrical signals into the human brain without causing damage to the human brain is the biggest problem.
In Chinese terms, everything is difficult at the beginning.
Lately we've been exploring how to do this. "
After Li Miaomiao finished chatting with Zheng Li, he sent an email to ask Li Wanqing through the internal email system.
Because not only has there been no new research progress in the Lion City R&D Center recently, but also the consumption curve of experimental monkeys in Lion City has increased significantly in the past two months.
You must know that after the soul certification, the price of the experimental monkey increased ten times than before.
Pharmaceutical companies are trying to find alternatives to laboratory monkeys because the cost of using laboratory monkeys is too high.
Due to the surge in clinical trial costs, a large number of small and medium-sized pharmaceutical companies have gone bankrupt.
Nowadays, the capital required for a small molecule drug from research and development to official launch starts at one billion yuan. Small and medium-sized pharmaceutical companies simply cannot bear it.
The surge in costs has caused the cro industry to become more prosperous, and a large number of European and American pharmaceutical companies have outsourced basic research and development to cro companies in China.
The market value of China's cro industry leader has more than tripled.
Another paradoxical point is that the experimental results of using other experimental animals to replace experimental monkeys are not recognized in some countries.
The drug regulatory agencies in these countries require that experimental monkeys must be used for experiments before they allow pharmaceutical companies to conduct human clinical trials.
Because they believe that drugs will not be sufficiently convincing if they have not undergone soulful biological experiments.
Most of these countries are underdeveloped and developing countries, and they are quite superstitious.
But there is one exception, and that is Amerikan. Americen came to the market firstly because of the high level of superstition, and secondly because they hope to raise the bar in the field of innovative drugs.
After Li Wanqing sent a video request to Zheng Li, he received consent.
Li Wanqing continued: "We have conducted various experiments on experimental monkeys, but so far there are no good results."
The full English name of vr is virtual reality, which means virtual reality.
It's just that in the domestic context, VR and virtual reality are separated, and virtual reality is considered to be higher-end than the Metaverse, and then the Metaverse is higher-end than VR.
In fact, the earliest concept of virtual reality can be traced back to the 1950s.
If people of that era were to use today's VR technology, they would definitely feel that this thing was more advanced than the virtual reality technology they imagined.
It’s just that people’s appetites are being whittled away by increasingly iterative technological supplies.
Previous VR technology was not considered virtual reality.
It wasn't until Kechuang Future's brain-computer connection VR came out that everyone felt that they could barely get involved with the Metaverse.
The research and development tasks assigned to Li Wanqing by Kechuang Biotechnology are to make a big step forward on the existing technology.
First, nerve cells generate electrical signals that carry information.
Although neurons are not inherently good conductors of electricity, they have evolved sophisticated mechanisms due to millions of years of evolution.
By generating electrical signals based on the flow of ions across their plasma membrane.
Normally, neurons develop a negative potential called the resting membrane potential, which can be measured by recording the voltage between the inside and outside of the nerve cell.
The action potential eliminates the negative resting potential and makes the transmembrane potential transiently positive.
Action potentials travel along the length of an axon and are the fundamental signals in the nervous system that carry information from one place to another.
The generation of resting and action potentials can be understood in terms of the selective permeability of nerve cells to different ions and the normal distribution of these ions across the cell membrane.
In fact, people have already realized the conversion of external signals into neural signals, which is vibration.
Vibrations in the air produce sound, which is further converted into neural signals that the brain can process.
There are approximately 110 species present in our genome.
These proteins are involved in processes such as cell composition and intercellular signaling.
At the heart of the system is a bundle of fine hairs deep in the cochlea, which are connected by protein chains called "tip links."
When the cochlea vibrates in response to sound, the hairs move, causing the tip connections to stretch and open ion channels in the hairs.
When positively charged ions flow in, they create electrical signals that the brain uses to process sound.
These links are composed of two proteins, cadherin 23 and protocadherin 15.
The area where the two proteins meet is more flexible than other areas in the body.
Calcium in the endolymph, the fluid within the ear's body, binds to proteins and helps increase the strength and stiffness of the tip link.
Amino acids that regularly bind calcium are even found in the long protocadherin-15 sequence.
This protein link causes mechanical vibrations, which are sounds that are converted into electrical signals that the brain can understand.
(The above concepts come from the papers on cell structure and function by Rachelle Gaudet, professor of biology at Harvard University, and Marcos Sotomayor, assistant professor at Ohio State University.)
Li Wanqing's attempt to study how to convert electrical signals into neural signals in this direction failed.
He hopes that electrical signals will first be converted into mechanical vibrations and then into neural signals that the brain can recognize.
But he found that the biggest problem in this direction is that mechanical vibrations are not effective either with sound or with sound.
Being stuck in the middle, unable to move forward or backward.
You must know that the brain is a site of high electrochemical activity.
There are approximately 100 billion neurons operating at a frequency of 5-50 action potentials per second.
Slight low-frequency vibrations cannot affect the human brain at all.
The reason why so many neural signals can be converted into electrical signals is also due to the improvement of computer performance.
Computers can capture electrical impulses in the brain and then analyze them to figure out an individual's true intentions.
However, how to convert electrical signals into neural signals while also affecting human senses is currently almost an unsolvable problem for humans.
This problem is equally difficult for Zheng Li.
Because what he knows is a biotechnological solution.
It is unlikely that he would come up with biocomputer-related technologies at Blue Star.
As long as he takes out the brain-computer connection technology based on biological computers, all countries will know that he belongs to Merlin.
He wasn't ready yet.
Kechuang Biotechnology releases virtual reality products and becomes a larger monopoly company, which actually does not mean much to him.
Zheng Li has used the resources of Kechuang Biotechnology to build many research facilities to serve him alone.
More money doesn't make it better.
And now that he is the director of Cern, Science and Technology Biotech can bring him even less help.
However, after being at Blue Star for so long, Zheng Li has long since become a master in the computer field.
After listening to Li Wanqing's explanation, he said:
“In fact, we can stimulate neurons through electrical stimulation.
The problem at hand is that biological neurons don't work in a binary fashion.
Information is encoded during the discharge process.
The number of pulses per pulse, the frequency of the pulses, and the time it takes for the pulses to reach their destination.
This does not refer to the duration, but the instant of arrival.
and the fine structure of emergencies over which we have no control over the information transmitted through the axon. "
What Zheng ideally wanted was to remind Li Wanqing by making insinuations to see if he could bring him some solutions.
“We can learn from how microscopic biological communities use macroscopic chemical-electrical signal converters to convert electrical signals into chemical outputs.
Nerve cells in microscopic organisms convert electrical signals into chemical outputs to facilitate the active transmission of information through the nervous system.
The single-cell microorganism Saccharomyces cerevisiae, for example, directly reads local chemical concentrations and converts them into dynamic electric fields that are evenly distributed across the fungal population.
A dual-feedback gene circuit of chemical excitability precisely regulates the expression of active potassium channels and coordinates cyclic firing of the plasma membrane potential (PMP).
This research and development path may be able to bring you some ideas.
You can check out the research results in this field. I will send you some valuable papers that I have read in this subdivided field later. "
Li Wanqing felt relieved. It turned out that there were times when Zheng Li didn't know how to solve the problem.
Because of Zheng Li's powerful ability shown before, he felt a lot of pressure.
If your boss is too awesome, will you appear too incompetent?
Now Zheng Li only talked about some ideas, making Li Wanqing realize that Zheng Li was not omniscient and omnipotent.
However, Li Wanqing was deeply impressed by Zheng Li's ability to handle various papers and subdivisions at his fingertips.
You must know that the direction Zheng Li just mentioned is microbial communities, which has nothing to do with brain science.
Zheng Li has even read a lot of papers in this kind of niche field, because Zheng Li said that some valuable papers should be sent to him.
The research atmosphere of Blue Star resulted in a lot of content that was very inspiring to Zheng Li.
In the Mage Alliance, it is very expensive to see other people's cutting-edge research results.
Even the Dharma God can't afford it.
At Blue Star, the latest research results of scientists are eager to be seen by everyone. The more citations, the better.
However, Blue Star’s mechanism also has drawbacks. First, there is serious flooding of papers in certain fields.
Secondly, many ideas are actually very good, but they are researched just for publishing articles.
In other words, even if the data cannot match the desired conclusion, the data will be processed to force the data to match the conclusion.
Secondly, it is difficult to conduct experiments, and all kinds of data and p-charts are forged in order to rush for time.
But in Zheng Li's view, even if there are various shortcomings, the flaws cannot hide the advantages.
Compared with the Mage Alliance, this environment is simply a paradise for mages.
Moreover, after Zheng Li's arrival, all countries have increased their investment in scientific research and policy guidance.
Especially in basic subject areas.
"Okay, I have a rough idea. Thank you, Director Zheng, for your valuable advice."
...
Time has come to the end of September in the blink of an eye, and China's lunar base has been basically completed.
In the first nine months of this year alone, astronauts have made three round trips from Blue Star to the moon.
Ever since China started building a space station orbiting the moon, it has been criticized by overseas media.
Not just Western media, but also media from Asan, Neon, Korea and other countries.
Neon and Korean media are lamenting that the gap between their country's aerospace industry and China's is getting wider and wider.
Asan's media is saying that it will take five years for them to catch up with China in the aerospace field.
Thanks to the successful construction of the lunar base, China has become the only country with territory outside the Blue Star.
Overseas media are trying to provoke conflicts in China every day.
So much so that the one who is most often cited to stir up local conflicts has gone to the moon three times, including four times last year, and none of them included female astronauts.
Even if the front-line fire fighters do not recruit female officers and soldiers, they can make tens of thousands of comments on Weibo.
Some women say that standards should be set instead of prohibiting women from enrolling from birth.
This can be noisy, let alone no female astronauts landing on the moon.
Female astronauts can go to the space station, why can't they land on the moon?
Of course, amid this turmoil, Microsoft launched their brain-computer connected VR device.
Kechuang Biotechnology also launched its own pico verse at the end of September.
“Welcome everyone on site and in front of the major live broadcast platforms to watch Kechuang Future’s 2026 autumn product launch.
This autumn product launch is mainly to release a new brain-computer connection VR.
As everyone must know, the brain-computer connected VR released this time is much more price-friendly than the futureverse released at the end of last year.
Major digital bloggers have almost exposed our pricing.
Next, let me give you a detailed introduction to the parameters..."
In the future, Kechuang will release brain-computer connection VR products for the mid-to-low-end, and the happiest people should be the software manufacturers.
Because this means the expansion of VR ecology.
Over time, brain-computer connection has become a standard feature of VR products.
There may have been players who would buy ordinary VR products before, but in recent years, fewer and fewer players have chosen to buy ordinary VR products.
Due to Kechuang Biotech’s monopoly in the field of brain-computer connection VR, the Europa Union and Amerikan have imposed huge fines of up to one billion yuan on Kechuang Future on more than one occasion.
Players have gradually realized that the immersive experience of ordinary VR is far inferior to that of brain-computer connected VR.
Instead of buying an ordinary VR, it is better to use a computer.
Especially after pico was merged into Kechuang Future, there were rumors that Kechuang Future would be a mid-to-low-end VR, and players would no longer buy ordinary VRs.
The party will never give up.
“The price of pico verse i is 5999rmb. If you choose to pre-order today, you can save another 300 yuan on this basis.
This offer is only available today. "
Pico is equivalent to directly cutting the price by half.
Under the temptation of an instant discount of 300, a large number of users placed orders.
It’s different from the Redmi press conference where they said they’d get an immediate discount of 300 when ordering today, and then the price would be directly reduced by 800 two weeks later.
Because Kechuang Future has a substantial monopoly on its products, it has particularly strict price controls.
Even on festivals like Double Eleven or June 18th, Kechuang Future would rather give out small gifts than reduce prices.
This is the attitude of being a high-end brand.
Even if the price is reduced, it is still when the inventory is cleared.
For example, the first generation of brain-computer connected VR two years ago will not be produced again in the future, so the price can be reduced.
