During this period, Wu Zhou was constantly testing the scope of use of Xiaowei and testing it.
Although, at this stage, Xiaowei has no way to directly invest in the market, because there is a high probability that it will bring about completely unknown changes.
However, AI assistance that matches the current stage of development, or even slightly exceeds the current stage of development, and perfectly fits the company's development will obviously be very beneficial to the company.
Wu Zhou used Xiaowei to produce a brand new company management ERP, operation assistant, scientific research assistant, etc.
After gradually entering into the company's operation work, within a few days, there were no negative comments from the feedback.
The efficiency is really too high.
For example, making forms and ppts before operations may require various skills.
But now as long as you describe what you need in text, or even pictures, the AI system currently used by the company can automatically produce it.
And after multiple applications, each user terminal will automatically record usage habits and needs, and even directly connect to the system.
For example, Liu Bin, Liu Fei, and Han Xinyan, who work in the operations department, previously had to do sales daily reports, inventory daily reports, product flow analysis, and industry flow change trend charts every day.
Abnormal traffic, competitive product dynamics, activity effect analysis, new product discovery, etc., various forms.
Now, it is almost a matter of turning on the computer, logging into the system, waiting for two or three minutes, and after exporting the data from the database in the background of the platform, it will automatically produce targeted tables and even provide a preliminary analysis report.
Greatly reduces the work of the operations department.
To make a simple comparison, Han Xinyan estimated that it would take several hours to make these tables every day, mainly due to various backends, which took time to download, and there was a lot of data. Although they have generated automatic forms, they still have to check and filter.
Now it only takes 3 minutes after all these forms are generated.
Comparison between an hour and three minutes.
In the past, the operations department felt that there were not enough manpower because there were too many chores. Now, suddenly, I felt that the manpower was somewhat sufficient.
As for Liu Bin, he is the general person in charge of the operations department. Every day, he opens N browsers on his computer and checks them at any time in various backends.
And now everything is integrated into the company's AI system page.
Just opening this interface is enough.
One page integrates detailed data from all online platforms.
And after using it for a few days, I even learned his analysis habits, and even produced preliminary operational suggestions based on his past operational decisions and operational effects.
The same amount of work that Liu Bin used to take a day, and it was a brain-breaking task, can now be completed directly in less than an hour, and it even seems to be completed better.
"I feel like I'm about to lose my job." Some people couldn't help but think.
"If you don't want to lose your job, you need to be sensible and use your imagination. In the future, imagination will be your ability."
Rational logic, AI performance is much stronger than ordinary people.
On the other side is the research center of Aiying Biology.
Cui Min is a young senior chemist at Aiying Biotechnology. Before coming to Aiying Biotechnology, she was engaged in scientific research at a university. Unfortunately, her leader did not trust her very much, and the school wanted to apply. R&D funds require seniority and connections, which immediately extinguished most of her enthusiasm for scientific research and even gave her the idea of leaving China.
And coincidentally, during that time, the headhunter from Aiying Group found her and offered her very generous salary conditions.
It is definitely impossible to say that she is not interested in the salary and remuneration. After all, she is also a human being and cannot be ascetic. Moreover, she still has a family and needs to live, and she needs money in all aspects.
Of course, what she values most is scientific research, and the promise given by Aiying Group is that it will give her a sufficient scientific research budget and completely free space to perform. This level of trust once made her feel impossible.
Could it be that he was a liar? In the end, he finally confirmed that Aiying Group was China's most famous philanthropist on the Internet, and visited the company in person. After the contract in black and white at the company headquarters was placed in front of him, Cui Min still remembered his disbelieving eyes at that time.
Because even though he had never looked for a job, he knew that this contract was too loose and had almost no binding force on the employee.
"Is this the type of contract that Aiying Biotech recruits?"
"Of course not. Aiying Company treats different talents and applies completely different contract terms. You are an A-level talent selected by the group, so the contract terms given to you are of course the best in the company at present."
"Me? Grade A? The best? Are you sure you know my research findings? What I want to research is new drugs for rare diseases. It is not easy to generate profits?" Cui Min couldn't believe it.
"certainly."
With a skeptical attitude, Cui Min still signed. The salary was more than twenty times that of the school, and the funding for scientific research projects was increased by a hundred times. With such good conditions, she would be a fool not to sign.
Working for one year is almost equivalent to working in school for a lifetime.
In the subsequent work, although she only worked for less than 3 months, Cui Min was once again grateful for her decision at that time. Fortunately, she did not choose to go abroad.
The Aiying Group's original promise to her was fully fulfilled, or even exceeded.
I didn't expect that it was just a cross-border enterprise in China, but it could provide such a favorable scientific research environment.
Of course, the most important thing is that there are too many people around me who can learn and communicate with me, and almost all of them are people who love scientific research.
This kind of environment where she is surrounded by people of the same kind and can help her improve her scientific research level really makes her feel like she is dreaming.
During this time, she was looking for a molecule that could inhibit an enzyme related to a genetic disease. She tested hundreds of candidate substances, and there were three candidates, but they still did not meet her expectations and needed to continue testing.
On this day, the head of the company's information department called her into the office and introduced her to Li Yang. Li Yang was a data scientist at Aiying Group. He had been working as a data supporter in the Aiying Biodata Center department. Work.
After Cui Min entered the door.
"Hello, my name is Li Yang. I am a data scientist at the company. The company has recently developed a new generative model that can help your scientific research project." Li Yang got straight to the point without any politeness.
Cui Min prefers this method of communication because it saves time.
"Hello, I'm Cui Min, a senior chemist in the company. How can I help?"
Cui Min was skeptical about what Li Yang said. Of course she knew the generative model, but its reliability and accuracy were very questionable. And from the bottom of her heart, she doesn’t believe that a generative model can replace human expertise and intuition.
However, based on her good experience in Aiying Biological Research during this period, she did not refuse.
Li Yang then followed Cui Min to her lab, where he connected his laptop to her workstation.
He opened an application and displayed a very simple-looking interface with several options and parameters.
"Before we start, we need to determine the target affiliation." Li Yang said. "For example, what kind of molecules do you want to find? Of course, this is more complicated. Do you have any data on the binding affinity of your candidate substances?"
"Yes." Cui Min said and gestured to her assistant who was not far away. Her assistant quickly started operating on the computer. After a while, a set of data was presented.
"Okay, next I will upload them to this model." Li Yang said, took out his mobile phone and directly took pictures of the relevant data, one page, two pages, three pages. While taking the picture, the relevant data information was instantly After a while, they appeared on the computer screen one after another.
"You can check it to see if there are any errors or omissions in the data. If not, I will let him run it." Li Yang said.
Cui Min nodded and checked for a moment.
"no problem."
After Li Yang clicked, the interface started to run initially and entered the next page.
"Okay, now we can set the range of IC50 values we want to generate." Li Yang said. He moved the two sliders on the screen until they read 0-10 nM.
Cui Min was slightly surprised by Li Yang's operation, but didn't say anything.
"This small value?" Assistant Cui Min said in surprise. Generally, the smaller the ic50 value, the stronger the specificity of the antibody and the better the effect. "We don't have a candidate substance with such a low IC50 value yet."
"We'll find out later." Li Yang said with a smile, showing great confidence. "It can explore regions of chemical space that you haven't explored before."
He clicked on another option that allowed him to specify some additional constraints on the generated molecules.
"We also need to make sure that our molecules are drug-like compounds." After all, he is a data engineer hired by the Aiying Group with a high salary. He has worked here for such a long time, and he already understands a lot of common professional knowledge. So often before Cui Min could say anything, Li Yang would have already opened the corresponding page.
"This means they should have reasonable molecular weights, logP values, solubility, etc. We can use some common filters like Lipinski's rule of five or QED scores to filter out undesirable compounds."
He checked some boxes on the screen and adjusted some thresholds accordingly.
"Is there anything else?" he asked Cui Min.
"Well, need to avoid molecules that are too similar to the ones I already have," Cui Min said. “No need to waste time and resources testing duplicate or near-duplicate compounds.”
Li Yang nodded, and then entered 0.8 as the cutoff value for the Tanimoto similarity coefficient, a commonly used indicator for comparing molecular structures.
"Then it starts?" Li Yang turned around and asked again.
Cui Min hummed softly.
A button labeled "Generate" was then clicked. The model starts working, showing a progress bar and some statistics on the screen. Alice watched nervously, wondering if anything useful would emerge.
After about 3 minutes, the model completed generating 1000 molecules that met all conditions. It sorts them according to their predicted IC50 values, from lowest to highest, and displays them in a tabular format as 3D structures. It also highlights their key features such as functional groups, rings or heteroatoms.
At this moment, Cui Min no longer had the calmness before, with a look of disbelief.
She walked to the computer and scrolled quickly, looking at each molecule carefully. The more she looked at them, the more surprised she became. These molecules were indeed diverse and innovative, showing backbones, substituents, and connection methods that were different from her candidate substances. Some of them looked familiar, similar to known drugs or natural products; others were completely unfamiliar, displaying structures she had never seen before. She selected a molecule that had a complex ring structure with some oxygen and nitrogen atoms.
Cui Min asked Li Yang without looking back, "Can this molecule be synthesized? Is there a synthesis path?"
"Of course." Li Yang nodded. "Our model can not only generate molecular structures, but also synthetic routes. You only need to click this button to see the detailed steps and reaction conditions."
As he spoke, Li Yang moved the mouse, paused briefly at a position to show Cui Min, and then clicked lightly. The screen instantly jumped to a new window, showing the synthesis route of the molecule. It consists of four steps, each of which gives the required reagents, solvents, temperature, and time.
"I never thought that new drugs could be designed and synthesized in this way." The shock on Cui Min's face was still there, but she could no longer suppress her smile.
This is really, really useful to her.
"Teacher Cui, am I going to lose my job?" Assistant Cui Min on the side had a sad face, because the work just now was the work he did on weekdays, but what is certain is that his workload in several months It's not as good as the results of this system in just a few minutes.
At this moment, he felt that his previous work had completely lost its meaning.
"Not yet, you can do something else," Cui Min said without looking back. At this moment, she was constantly clicking on the synthesis paths of compounds one after another.
His eyes were full of surprise.
(End of chapter)
